Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Paula Loos"'
Autor:
Li Li, Sashi Nadanaciva, Zdenek Berger, Wei Shen, Katrina Paumier, Joel Schwartz, Kewa Mou, Paula Loos, Anthony J Milici, John Dunlop, Warren D Hirst
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85815 (2013)
Parkinson's disease (PD) is the second most common neurodegenerative disease. A key pathological feature of PD is Lewy bodies, of which the major protein component is α-synuclein (α-syn). Human genetic studies have shown that mutations (A53T, A30P,
Externí odkaz:
https://doaj.org/article/d66a11a109554bf685a5e666188f4884
Autor:
John Dunlop, Paul Galatsis, Kieran F. Geoghegan, Hualin Xi, Paula Loos, Greg Luerman, Chuong Nguyen, Harry Samaroo, G. Stephen Noell, Andrés Hurtado-Lorenzo, Elie Needle, Warren D. Hirst
Publikováno v:
Journal of Neurochemistry. 128:561-576
Genetic mutations in leucine-rich repeat kinase 2 (LRRK2) have been linked to autosomal dominant Parkinson's disease. The most prevalent mutation, G2019S, results in enhanced LRRK2 kinase activity that potentially contributes to the etiology of Parki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e246fffdb7d2b6338743e5fd5a4fbd7d
https://doi.org/10.1111/jnc.12483
https://doi.org/10.1111/jnc.12483
Autor:
Philip A. Carpino, Kieran F. Geoghegan, Adam G. Schwaid, Chuong Nguyen, Jean Kanyo, Samit Kumar Bhattacharya, Chunyan Su, Jiang Wu, Paula Loos, Robert L. Dow, Kathryn L. Stone, Leonard Buckbinder
Publikováno v:
ACS chemical biology. 10(12)
Mitogen-activated protein kinase 4 (MAP4K4) regulates the MEK kinase cascade and is implicated in cytoskeletal rearrangement and migration; however, identifying MAP4K4 substrates has remained a challenge. To ascertain MAP4K4-dependent phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c48e831d69ad4fca251e623c7503e5
https://pubmed.ncbi.nlm.nih.gov/26422651
https://pubmed.ncbi.nlm.nih.gov/26422651
Autor:
Warren D. Hirst, Katrina L. Paumier, John Dunlop, Kewa Mou, Joel W. Schwartz, Wei Shen, Anthony J. Milici, Paula Loos, Sashi Nadanaciva, Zdenek Berger, Li Li
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85815 (2013)
PLoS ONE
PLoS ONE
Parkinson’s disease (PD) is the second most common neurodegenerative disease. A key pathological feature of PD is Lewy bodies, of which the major protein component is α-synuclein (α-syn). Human genetic studies have shown that mutations (A53T, A30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9025e3c2207b9c0c845451e6de2db172
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24392030/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24392030/?tool=EBI
Autor:
Tracy M. Brown, Lida H. Kimmel, Carol D. Hicks, Paula Loos, Karl E.G. Richter, Robin J. Kleiman
Publikováno v:
Alzheimer's & Dementia. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::646c9b1313636fab5c343e5dd74dfd91
https://doi.org/10.1016/j.jalz.2010.05.890
https://doi.org/10.1016/j.jalz.2010.05.890
Autor:
Paula Loos, Jeffrey P. Demuth, Alan D. Proia, Ronald L. Terjung, Alex Varbanov, Hsiao T. Yang, Michael G. Davis, Elaine Eby-Wilkens, Angela Qu, Brian W. Howard, Kevin G. Peters, Andrew N. Carr
Publikováno v:
Cardiovascular research. 69(4)
Objective: Studies have reported that administration of stromal cell-derived factor-1 (SDF-1), the ligand for the G-protein coupled receptor CXCR4, increased collateral blood flow in a mouse model of vascular insufficiency via recruitment of endothel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bfa8af6694ca7299c44efbe83c6220
https://pubmed.ncbi.nlm.nih.gov/16409996
https://pubmed.ncbi.nlm.nih.gov/16409996