Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Paula Leandro-Garcia"'
Autor:
Judith Versteegh, Joeri Johannes Petrus De Wit, Arthur Oubrie, Niels Hoogenboom, Tjeerd Barf, Maaike van Hoek, Bert Kazemier, Allard Kaptein, Carsten Schultz-Fademrecht, Paula Leandro-Garcia, Frank Wijnands, John Dulos, Martin Jaeger, Bas van de Kar, Jeroen A.D.M. de Roos, Gerard Mt Vogel, Mario van Zeeland, Edwin de Zwart, Vera de Kimpe, Judith Borsboom
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(12)
The identification of a potent, selective, and orally available MK2 inhibitor series is described. The initial absence of oral bioavailability was successfully tackled by moving the basic nitrogen of the spiro-4-piperidyl moiety towards the electron-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f22fbd250c5e4013286b26a2ff642b
https://pubmed.ncbi.nlm.nih.gov/21565498
https://pubmed.ncbi.nlm.nih.gov/21565498
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
instname
In this work, rosuvastatin has been used to gain insight into the molecular basis of statin photosensitization. This lipid-lowering drug, also known as ¿superstatin¿, contains a 2-vinylbiphenyl-like moiety and has been previously described to decom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070637e6afa491ca6c830ff892faec4f
Publikováno v:
Chemical Research in Toxicology; Oct2011, Vol. 24 Issue 10, p1779-1785, 7p