Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Paula Lam"'
Autor:
Jiajun Yap, Jimin Yuan, Wan Hwa Ng, Gao Bin Chen, Yuen Rong M. Sim, Kah Chun Goh, Joey Teo, Trixie Y. H. Lim, Shee Min Goay, Jia Hao Jackie Teo, Zhentang Lao, Paula Lam, Kanaga Sabapathy, Jiancheng Hu
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Hairy cell leukemia (HCL) is a B-lymphoma induced by BRAF(V600E) mutation. However, introducing BRAF(V600E) in B-lymphocytes fails to induce hematological malignancy, suggesting that BRAF(V600E) needs concurrent mutations to drive HCL ontoge
Externí odkaz:
https://doaj.org/article/3a07a7fcfb1b4d6f9d06508cc1d554f2
Autor:
Constanza Bianchi, Paula Lam
Publikováno v:
Journal of Services Marketing. 33:721-734
Purpose The purpose of this paper is to investigate how family members co-create value and improve the well-being of patients with chronic developmental disorders, such as Asperger syndrome (AS) that undertake permanent therapy services. Design/metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb6c292e23dc88ba63f78b72b85b673
https://doi.org/10.1108/jsm-12-2018-0365
https://doi.org/10.1108/jsm-12-2018-0365
Publikováno v:
Biotechnology advances. 54
The immune system is tasked to keep our body unharmed and healthy. In the immune system, B- and T-lymphocytes are the two main components working together to stop and eliminate invading threats like virus particles, bacteria, fungi and parasite from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9017669de4c6705f0c64019814866fd9
https://pubmed.ncbi.nlm.nih.gov/34801662
https://pubmed.ncbi.nlm.nih.gov/34801662
Autor:
Kah Chun Goh, Paula Lam, Zi Heng Tee, R. N. V. Krishna Deepak, Zizi Tian, Manju Payini Mohanam, Wan Hwa Ng, Jiajun Yap, Jiancheng Hu, Zhongzhou Chen, Hao Fan, Ufuk Degirmenci, Yuen Rong M. Sim, Alicia Foo
Publikováno v:
Science Advances
The stabilized R-spine of oncogenic BRAF mutants impairs RAF inhibitor association and confers drug resistance.
Although targeting BRAF mutants with RAF inhibitors has achieved promising outcomes in cancer therapy, drug resistance remains a rema
Although targeting BRAF mutants with RAF inhibitors has achieved promising outcomes in cancer therapy, drug resistance remains a rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8e2a764f7e996f6be8f71e37fde484
http://europepmc.org/articles/PMC8189578
http://europepmc.org/articles/PMC8189578
Autor:
Ana Vaughan-Malloy, Phillip Hahn, Paula Lamagna, Jenny Chan Yuen, Dionne Graham, Jennifer Ormsby
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 4, Pp s2-s2 (2024)
Background: Per the Centers for Disease Control and Prevention, health equity stipulates all have a fair, just opportunity to attain their highest level of health. Limited evidence exists for disparities in health equity and healthcare-associated inf
Externí odkaz:
https://doaj.org/article/bb32b6d89b0a499c9d907cbcf9addce9
Publikováno v:
Revista CIDOB d'Afers Internacionals, Iss 131, Pp 185-210 (2022)
One of the main aims of the parliamentary diplomacy of the European Parliament (EP) is to safeguard democracy and human rights around the world. Venezuela is a paradigmatic case, especially since Nicolás Maduro came to power in 2013 and political re
Externí odkaz:
https://doaj.org/article/c3e01f5029a3432d9924cda774b6dc08
Autor:
Jerry K Y, Chan, Paula, Lam
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1416
Mesenchymal stem cells (MSCs) possess some unique features (inherent tumor tropism, anti-inflammatory and immunosuppressive properties) that are not commonly found in conventional anti-cancer agents. These cells are known to secrete a vast array of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::433002478e94c115022ddb60217e9fde
https://pubmed.ncbi.nlm.nih.gov/27236690
https://pubmed.ncbi.nlm.nih.gov/27236690
Publikováno v:
Oxidative Stress in Applied Basic Research and Clinical Practice ISBN: 9783319307039
Glioblastoma multiforme (GBM) is the most aggressive human brain tumor. Standard of care includes surgical resection, radiation therapy, and concomitant adjuvant chemotherapy with temozolomide (TMZ) which can only modestly improve median survival. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0d198feee9ec7e3c34c29d192e76939
https://doi.org/10.1007/978-3-319-30705-3_17
https://doi.org/10.1007/978-3-319-30705-3_17
Publikováno v:
Molecular Therapy. 12:144-152
Glial cell invasion is a multistep cellular process that involves a complex system of tightly regulated proteases (matrix metalloproteinases; MMPs) and their endogenous inhibitors (tissue inhibitors of metalloproteinases; TIMPs) to mediate the degrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca191bed28b2e9b2de757299d1dc04b
https://doi.org/10.1016/j.ymthe.2005.02.028
https://doi.org/10.1016/j.ymthe.2005.02.028
Autor:
Shreya Singh Beniwal, Paula Lamo, Ajeet Kaushik, Dionisio Lorenzo Lorenzo-Villegas, Yuguang Liu, ArunSundar MohanaSundaram
Publikováno v:
Biosensors, Vol 13, Iss 10, p 926 (2023)
Colorectal cancer (CRC) is a prevalent and potentially fatal disease categorized based on its high incidences and mortality rates, which raised the need for effective diagnostic strategies for the early detection and management of CRC. While there ar
Externí odkaz:
https://doaj.org/article/1a4ba4818f4248d38cd5f22eed2859ea