Výsledky vyhledávání - "Paula Ladeira Ortolani"

Akademický článek

Identification and characterization of the first endogenous phospholipase A2 inhibitor from a non-venomous tropical snake, Boa constrictor (Serpentes: Boidae)

Autor: Consuelo L. Fortes-Dias, Diego Henrique Fagundes Macedo, Rafaella Pereira Barbosa, Gabriel Souza-Silva, Paula Ladeira Ortolani

Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 26 (2020)

Abstract Background: Endogenous phospholipase A2 inhibitors from snake blood (sbPLIs) have been isolated from several species around the world, with the primary function of self-protection against the action of toxic phospholipases A2. In American sn

Externí odkaz: https://doaj.org/article/7e2527ab554e41e594b21d6f5eafb2cb

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Akademický článek

Identification, description and structural analysis of beta phospholipase A2 inhibitors (sbβPLIs) from Latin American pit vipers indicate a binding site region for basic snake venom phospholipases A2

Autor: Consuelo Latorre Fortes-Dias, Carlos Alexandre H. Fernandes, Paula Ladeira Ortolani, Patrícia Cota Campos, L.A. Melo, Liza Figueiredo Felicori, Marcos Roberto M. Fontes

Publikováno v: Toxicon: X, Vol 2, Iss , Pp - (2019)

Several snake species possess, in their circulating blood, endogenous PLA2 inhibitors (sbPLIs) with the primary function of natural protection against toxic enzymes from homologous and heterologous venoms. Among the three structural classes of sbPLIs

Externí odkaz: https://doaj.org/article/dd8d7d5909c846a295bc8b5e3ee5dc4c

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Dissertation/ Thesis

Indução de edema de boca em ratos como modelo de detecção de drogas anti-inflamatórias de ação local

Autor: Paula Ladeira Ortolani

Publikováno v: Biblioteca Digital de Teses e Dissertações da UFMGUniversidade Federal de Minas GeraisUFMG.

The present study aimed to develop an experimental model of acute inflammation in oral cavity of rats, it has been considered as a standard of comparison the hind paw edema of the rats. The edema rating was performed in parallel to the extravasation

Externí odkaz: http://hdl.handle.net/1843/BUOS-8MRLXT

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Varespladib (LY315920) prevents neuromuscular blockage and myotoxicity induced by crotoxin on mouse neuromuscular preparations

Autor: Thales Augusto Gonçalves de Abreu, Consuelo Latorre Fortes-Dias, Paula Ladeira Ortolani, Natália Muradas Valério Souza, Êmylle Karoline Ramos Pinto, Fernanda Valadares Maciel, Walter L.G. Cavalcante

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 202

Varespladib (LY315920) is a synthetic phospholipase A2 (PLA2) inhibitor that has been demonstrating antiophidic potential against snake venoms that present PLA2 neurotoxins. In this study, we evaluate the capacity of Varespladib to inhibit the neurom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc7d83c4ec06382be4819f6a7ae6d0f
https://pubmed.ncbi.nlm.nih.gov/34562493

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Hepatitis B and C prevalence in waste pickers: a global meta-analysis

Autor: Paula Ladeira Ortolani, Marcos Paulo Gomes Mol, Sonia Maria Dias, Vanessa Resende Nogueira Cruvinel, Gabriel Souza-Silva, Tara Rava Zolnikov

Publikováno v: Journal of public health (Oxford, England). 44(4)

Background The objective of this research was to use a meta-analysis to understand the prevalence of hepatitis B or C in waste pickers worldwide. Methods Epidemiological studies on hepatitis B and C in waste pickers were included adopting a systemati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63065a369c9168ffe9d4d9394f2069fa
https://pubmed.ncbi.nlm.nih.gov/34296276

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Crotalus Neutralizing Factor (CNF) inhibits the toxic effects of Crotoxin at mouse neuromuscular preparations

Autor: Walter L.G. Cavalcante, Thales Augusto Gonçalves de Abreu, Êmylle Karoline Ramos Pinto, Paula Ladeira Ortolani, Fernanda Valadares Maciel, Henrique Freitas Ferreira Reis, Natália Muradas Valério Souza, Consuelo Latorre Fortes-Dias

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 191

Crotalus Neutralizing Factor (CNF) was the first phospholipase A2 inhibitor isolated from the plasma of the South American rattlesnake (Crotalus durissus terrificus). Previous biochemical and biophysical studies demonstrate an interaction of CNF with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65272d8774e8f5f66182276508da48fe
https://pubmed.ncbi.nlm.nih.gov/33387548

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Identification and characterization of the first endogenous phospholipase A2 inhibitor from a non-venomous tropical snake, Boa constrictor (Serpentes: Boidae)

Autor: Rafaella Pereira Barbosa, Consuelo Latorre Fortes-Dias, Gabriel Souza-Silva, Diego H. Macedo, Paula Ladeira Ortolani

Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases v.26 2020
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 26, Article number: e20190044, Published: 13 MAR 2020
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 26 (2020)

Background: Endogenous phospholipase A2 inhibitors from snake blood (sbPLIs) have been isolated from several species around the world, with the primary function of self-protection against the action of toxic phospholipases A2. In American snakes, sbP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1d543e0b5b1738ae3db07a4016dbce
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100305

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Autor: Liza Felicori, Paula Ladeira Ortolani, Carlos A.H. Fernandes, Lutiana Amaral de Melo, Consuelo Latorre Fortes-Dias, Marcos R.M. Fontes, Patrícia Cota Campos

Publikováno v: Toxicon: X
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Toxicon: X, Vol 2, Iss, Pp-(2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d9d92f4dfa5d463184cb28d470dfb0
http://europepmc.org/articles/PMC7286088

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Immunodetection of toxins in historesin-embedded sections of Phoneutria nigriventer venom glands using laser confocal scanning microscopy

Autor: Carlos Chávez-Olórtegui, Paulo Filemon Paolucci Pimenta, Consuelo Latorre Fortes-Dias, Marta N. Cordeiro, Luciana Maria Silva, Layla Mosqueira Moura, Rafael Nacif-Pimenta, Paula Ladeira Ortolani

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 167

In the last decades, main advances were achieved in the identification, structural and pharmacological characterization of Phoneutria nigriventer toxins. However, studies on the venom-producing apparatus are rare. Presently, we applied immunolabeling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de15cc8fdb0c9358dce8d05133f2a044
https://pubmed.ncbi.nlm.nih.gov/31207353

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Insights on the structure of native CNF, an endogenous phospholipase A2 inhibitor from Crotalus durissus terrificus, the South American rattlesnake

Autor: Wallance Moreira Pazin, Mario de Oliveira Neto, Lutiana Amaral de Melo, Marcos R.M. Fontes, Kelli Roberta Lobo, Roberto M. Fernandez, Paula Ladeira Ortolani, Carlos A.H. Fernandes, Consuelo Latorre Fortes-Dias, Márcia Helena Borges

Publikováno v: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1844:1569-1579

Several snake species possess endogenous phospholipase A2 inhibitors (sbPLIs) in their blood plasma, the primary role of which is protection against an eventual presence of toxic phospholipase A2 (PLA2) from their venom glands in the circulation. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0b87345d7a8e3700772b5b976dcf1a
https://doi.org/10.1016/j.bbapap.2014.05.001

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