Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Paula L. de Melo Souza"'
Autor:
Luane Ferreira Garcia, Douglas Vieira Thomaz, Kamila B. Japiassu, Eric de Souza Gil, Marize Campos Valadares, Kelly Carolina Frauzino Araújo, Evilanna Lima Arruda, Valéria de Oliveira, Paula L. de Melo Souza, Alane Pereira Cortez
Publikováno v:
Anti-cancer agents in medicinal chemistry. 20(14)
Background: The strategic development of therapeutic agents, capable of being targeted at their active sites, has been a major goal in treatment of cancer. The delivery of drugs for tumors has as its main challenge the development of safe and effecti
Autor:
Paula L. de Melo Souza, Valéria de Oliveira, Boniek G. Vaz, Francine Pazini, Evilanna Lima Arruda, Luciano M. Lião, Ricardo Menegatti
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:3177-3181
An efficient and rapid process for N-glycosylation of 5-(1-(3-fluorophenyl)-1H-pyrazol-4-yl)-2H-tetrazole-LQFM 021 (1), a new synthetic derivative of pyrazole with phosphodiesterase-3 (PDE-3) inhibitory action, vasorelaxant activity and low toxicity
Autor:
Paula L. de Melo Souza, Evilanna Lima Arruda, Luciano M. Lião, Boniek G. Vaz, Kamila B. Japiassu, Valéria de Oliveira, Elaine S. Nunes, Thays C. de Carvalho
Publikováno v:
Tetrahedron Letters. 57:4392-4394
The glycosylation of azidothymidine by Cunninghamella echinulata ATCC 9245 in a single step was achieved using whole cells in a stirred tank bioreactor (STR). Reaction conditions of 50 mg·mL −1 of 1 in PDSM medium at 28 °C for 168 h. After extrac
Autor:
Núbia C. de Paula, Diogo F. Nogueira, Maı́sa B Costa, François Noël, Paula L. de Melo Souza, Kelly C. F. Araújo Cordeiro, Valéria de Oliveira, Diego B. da Silva e Sousa
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(5)
A screening of fungal and microbial strains allowed to select the best microorganisms to produce in high yields some of the human metabolites of two benzodiazepine drugs, diazepam and clonazepam, in order to study new pharmacological activities and f
Publikováno v:
Revista Brasileira de Bioética; v. 6 n. 1-4 (2010); 69-84
Faced with the notorious opposition of the Catholic Church’s doctrine and family planning policies regarding conception and contraception, catholic doctors find themselves in an awkward situation when patients seek consultations regarding their des