Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paula L. Roesch"'
Publikováno v:
BioTechniques, Vol 42, Iss 3, Pp 378-381 (2007)
MicroRNA (miRNA) expression profiling is a powerful and commonly used methodology for assessing the relative levels of individual miRNAs in specific tissues. To achieve accurate results using miRNA microarray detection strategies, it is important tha
Externí odkaz:
https://doaj.org/article/75bc8a2ca0f745b89475f77687561d79
Publikováno v:
Infection and Immunity. 75:5298-5304
A d -serine deaminase (DsdA) mutant of uropathogenic Escherichia coli strain CFT073 has a hypercolonization phenotype in a murine model of urinary tract infection (UTI) due to increased virulence gene expression by an unknown mechanism (B. J. Haugen
Autor:
Tom W. Reppen, Andrei V. Blokhin, Darren H. Wakefield, Jon A. Wolff, David B. Rozema, Qili Chu, James E. Hagstrom, Paula L. Roesch, David L. Lewis, Stephanie Bertin, Jason Klein, So C. Wong
Publikováno v:
Proceedings of the National Academy of Sciences. 104:12982-12987
Achieving efficient in vivo delivery of siRNA to the appropriate target cell would be a major advance in the use of RNAi in gene function studies and as a therapeutic modality. Hepatocytes, the key parenchymal cells of the liver, are a particularly a
Autor:
Paula L. Roesch, Rodney A. Welch, Shahaireen Pellett, Peter Redford, Brian J. Haugen, Holly Hamilton
Publikováno v:
Infection and Immunity. 75:278-289
Deletional inactivation of the gene encoding d -serine deaminase, dsdA , in uropathogenic Escherichia coli strain CFT073 results in a hypermotile strain with a hypercolonization phenotype in the bladder and kidneys of mice in a model of urinary tract
Autor:
Angus T. De Souza, Tom W. Reppen, Xudong Dai, Hans Herweijer, Paula L. Roesch, Michelle J. Caguyong, Sherri Bloomer, Roger G. Ulrich, A.M. Menzie, Peter S. Linsley, James E. Hagstrom, David L. Lewis, Andrew G Spencer, Yudong He, Jon A. Wolff
Publikováno v:
Nucleic Acids Research
RNA interference (RNAi) has great potential as a tool for studying gene function in mammals. However, the specificity and magnitude of the in vivo response to RNAi remains to be fully characterized. A molecular and phenotypic comparison of a genetic
Autor:
Shahaireen Pellett, Andrew Bryan, Rodney A. Welch, Paula L. Roesch, Rebecca L. Moritz, Lindsay Davis
Publikováno v:
Infection and Immunity. 74:1072-1083
Genomic DNA sequence analysis of the uropathogenic Escherichia coli strain CFT073 revealed that besides the fimB and fimE recombinase genes that control the type 1 pilus fim phase switch, there are three additional fimB - and fimE -like genes: ipuA ,
Autor:
Brian J. Haugen, Stephanie Batchelet, Shahaireen Pellett, Frederick R. Blattner, Paula L. Roesch, Rebecca L. Moritz, Peter Redford, Rodney A. Welch
Publikováno v:
Molecular Microbiology. 49:55-67
Summary Although once thought to be unique to bacteria, d-amino acids are also produced by mammals. For example, d-serine is excreted in human urine at concentrations ranging from 3.0 to 40 µg ml−1. An epidemiological survey demonstrated that urin
Autor:
Ian C. Blomfield, Paula L. Roesch
Publikováno v:
Molecular Microbiology. 27:751-761
The leucine-responsive regulatory protein (Lrp) is a global regulator that controls the expression of numerous operons in Escherichia coli. Lrp can act as a repressor or as an activator of transcription with its effects being potentiated, repressed o
Publikováno v:
Journal of bacteriology. 187(18)
Phase variation of type 1 fimbriae of Escherichia coli requires the site-specific recombination of a short invertible element. Inversion is catalyzed by FimB (switching in either direction) or FimE (inversion mainly from on to off) and is influenced
Autor:
Harry L. T. Mobley, D. Stroud, Guy Plunkett, Michael S. Donnenberg, Frederick R. Blattner, Debra J. Rose, Rodney A. Welch, S. R. Liou, Paula L. Roesch, George F. Mayhew, Nicole T. Perna, David C. Schwartz, Jeremiah D. Hackett, Eric L. Buckles, Shiguo Zhou, Adam T. Boutin, David A. Rasko, Valerie Burland, Peter Redford
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(26)
We present the complete genome sequence of uropathogenic Escherichia coli , strain CFT073. A three-way genome comparison of the CFT073, enterohemorrhagic E. coli EDL933, and laboratory strain MG1655 reveals that, amazingly, only 39.2% of their combin