Supplementary Table 1 from The Heritability of Mammographic Breast Density and Circulating Sex-Hormone Levels: Two Independent Breast Cancer Risk Factors

Autor: Deborah J. Thompson, Douglas F. Easton, Mitchell Dowsett, Ruth M.L. Warren, Tina Audley, Jean Leyland, Judith Brown, Elizabeth Folkerd, Paula L. Smith, Jajini S. Varghese

PDF file - 108K, Regression estimates for associations between density measures and risk factors in the SIBS cohort.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5e2e446ff5fa7dec2db8fb19fe2d2e
https://doi.org/10.1158/1055-9965.22435659.v1

Data from Tagging Single-Nucleotide Polymorphisms in Antioxidant Defense Enzymes and Susceptibility to Breast Cancer

Autor: Bruce A.J. Ponder, Alison M. Dunning, Douglas F. Easton, Hannah Munday, Karen Redman, Robert Luben, Craig Luccarini, Paula L. Smith, Shahana Ahmed, Paul D. Pharoah, Arancha Cebrian

It is generally believed that the initiation of breast cancer is a consequence of cumulative genetic damage leading to genetic alterations and provoking uncontrolled cellular proliferation and/or aberrant programmed cell death, or apoptosis. Reactive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34303bb79932361279ad708fc1e578b4
https://doi.org/10.1158/0008-5472.c.6495257

Demographic and psychological predictors of alcohol use and misuse in autistic adults

Autor: Meng-Chuan Lai, Paula L. Smith, Laura Hull, William Mandy, Carrie Allison, Maya Bowri, Simon Baron-Cohen

Publikováno v: Bowri, M, Hull, L, Allison, C, Smith, P, Baron-Cohen, S, Lai, M C & Mandy, W 2021, ' Demographic and psychological predictors of alcohol use and misuse in autistic adults ', Autism, vol. 25, no. 5, pp. 1469-1480 . https://doi.org/10.1177/1362361321992668
Autism

This study explored demographic and psychological predictors of alcohol use and misuse in a high-functioning, community sample of 237 autistic adults aged 18–75 (mean = 41.92 and standard deviation = 13.3) recruited in the United Kingdom. An online

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98cf83f8c44af4edbccc385b386c899

The Heritability of Mammographic Breast Density and Circulating Sex-Hormone Levels: Two Independent Breast Cancer Risk Factors

Autor: Jean Leyland, Paula L. Smith, Douglas F. Easton, Mitchell Dowsett, Tina Audley, Elizabeth Folkerd, Jajini Varghese, Deborah J. Thompson, Ruth Warren, Judith E. Brown

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 21:2167-2175

Background: Mammographic breast density and endogenous sex-hormone levels are both strong risk factors for breast cancer. This study investigated whether there is evidence for a shared genetic basis between these risk factors. Methods: Using data on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04be47fef9d6128347dd1a09010aac3
https://doi.org/10.1158/1055-9965.epi-12-0789

Unsupervised data-driven stratification of mentalizing heterogeneity in autism

Autor: Simon Baron-Cohen, Michael V. Lombardo, Declan G. Murphy, Meng-Chuan Lai, Rosemary Holt, John Suckling, Amber N. V. Ruigrok, Bonnie Auyeung, Paula L. Smith, Christine Ecker, Bhismadev Chakrabarti, Carrie Allison, Michael C. Craig, Edward T. Bullmore, Francesca Happé

Publikováno v: Lombardo, M V, Lai, M-C, Auyeung, B, Holt, R J, Allison, C, Smith, P, Chakrabarti, B, Ruigrok, A N V, Suckling, J, Bullmore, E T, Ecker, C, Craig, M, Murphy, D G M, Happé, F & Baron-Cohen, S 2016, ' Unsupervised data-driven stratification of mentalizing heterogeneity in autism ', Scientific Reports, vol. 6, 35333 . https://doi.org/10.1038/srep35333

Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous. Novel approaches are needed to parse this heterogeneity to enhance precision in clinical and translational research. Applying a clustering approach taken from ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45adf9f505c277c32a9c9620c48be254