Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Paula Kuvaja"'
Autor:
Niina Sissala, Elisa Myllymäki, Florian Mohr, Riikka Halmetoja, Paula Kuvaja, Elitsa Y. Dimova, Peppi Koivunen
Publikováno v:
Physiological Reports, Vol 10, Iss 9, Pp n/a-n/a (2022)
Abstract Maternal overweight/obesity contributes significantly to the development of gestational diabetes, which causes risks to both mother and fetus and is increasing sharply in prevalence worldwide. Since hypoxia reprograms energy metabolism and c
Externí odkaz:
https://doaj.org/article/54fce013e6c945c38eeb7680e546cbf0
Publikováno v:
Anatomical Sciences Education. 15:341-351
To this day, autopsies and dissections have been essential in medical education, but declining autopsy numbers have endangered this long-standing tradition. Students' perceptions of these teaching methods should be constantly updated to help educator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f53d8c8981b0960cbca35682631f0f
https://doi.org/10.1002/ase.2073
https://doi.org/10.1002/ase.2073
Publikováno v:
Journal of forensic and legal medicine. 86
An adverse event in health care leading to death is a significant event when assessing patient safety. This study was designed in order to assess, how many iatrogenic deaths are registered in Finland annually, and what type of treatment they are most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f10dfb1b370975ae972b6da61063c39
https://pubmed.ncbi.nlm.nih.gov/34999300
https://pubmed.ncbi.nlm.nih.gov/34999300
Presumed adverse events in health care are a frequent indication for medico-legal autopsy in Finland
Publikováno v:
Forensic Science, Medicine, and Pathology
The medico-legal autopsy is an essential tool in investigating deaths caused by an adverse event in health care, for both clinical risk management and for professional liability issues. However, there are no statistics available regarding the frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0701b578bfdd51a4e178342e13f232ff
http://urn.fi/urn:nbn:fi-fe2020050424875
http://urn.fi/urn:nbn:fi-fe2020050424875
Autor:
I. Pasanen, Siri Lehtonen, Petri Lehenkari, E. Lehtilahti, Paula Kuvaja, Sini Skarp, Raija Sormunen, Mika Pietilä, R. Blanco Sequeiros
Publikováno v:
Europe PubMed Central
Tumor stroma has been recently shown to play a crucial role in the development of breast cancer. Since the origin of the stromal cells in the tumor is unknown, we have examined differences and similarities between three stromal cell types of mesenchy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a54929d63a347f17abe1e639e161d8
https://doi.org/10.1016/j.yexcr.2016.04.016
https://doi.org/10.1016/j.yexcr.2016.04.016
Publikováno v:
Anticancer research. 36(12)
Background/aim We have previously shown that cyclin A, B and E hold prognostic significance in endometrial endometrioid adenocarcinoma. The aim of this study was to investigate the impact of cyclin-dependent kinase inhibitor p27 on cancer-specific su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f3116e0913949efcde845ef5fac3c0
https://pubmed.ncbi.nlm.nih.gov/27919969
https://pubmed.ncbi.nlm.nih.gov/27919969
Publikováno v:
Human Pathology. 42:1103-1111
The objective of this immunohistochemical study was to explore the roles of Ki67 and p53 in conjunction with matrix metalloproteinase-2 and matrix metalloproteinase-9, tissue inhibitors of metalloproteinase-1 and tissue inhibitors of metalloproteinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088ce5fbd91f92130fb8facbc0b907a5
https://doi.org/10.1016/j.humpath.2010.11.013
https://doi.org/10.1016/j.humpath.2010.11.013
Publikováno v:
International Journal of Cancer. 123:846-851
TIMP-1 is a natural inhibitor of extracellular matrix degrading enzymes called matrix metalloproteinases. In addition to its capacity to inhibit matrix degradation, TIMP-1 has been shown to promote cell growth and inhibit apoptosis. The expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94cf9e5b9db5d1cf87ccc6b42e9bcc9
https://doi.org/10.1002/ijc.23531
https://doi.org/10.1002/ijc.23531
Autor:
Ritva, Nissi, Anne, Talvensaari-Mattila, Paula, Kuvaja, Paavo, Pääkkö, Ylermi, Soini, Markku, Santala
Publikováno v:
Anticancer research. 35(2)
Claudin proteins represent a large family of integral membrane proteins crucial for tight junction (TJ) formation and function and are abnormally regulated in several human cancers. The aim of the present study was to study the expression levels of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ee9de8f661a3bbf6ee65d4e4046bb38
https://pubmed.ncbi.nlm.nih.gov/25667483
https://pubmed.ncbi.nlm.nih.gov/25667483
Publikováno v:
Human Pathology. 37:1316-1323
Malignant tumors that are capable of invading surrounding structures and metastasizing possess certain capacities to cross tissue barriers. Matrix metalloproteinases (MMPs), especially gelatinases and their inhibitor molecules, are known to affect th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ece1fa5b40dbb0ea9ca804404973a7
https://doi.org/10.1016/j.humpath.2006.04.021
https://doi.org/10.1016/j.humpath.2006.04.021