Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Paula Katavolos"'
Autor:
Smadar Shiffman, Edgar A. Rios Piedra, Adeyemi O. Adedeji, Catherine F. Ruff, Rachel N. Andrews, Paula Katavolos, Evan Liu, Ashley Forster, Jochen Brumm, Reina N. Fuji, Ruth Sullivan
Publikováno v:
Journal of Pathology Informatics, Vol 14, Iss , Pp 100333- (2023)
Our objective was to develop an automated deep-learning-based method to evaluate cellularity in rat bone marrow hematoxylin and eosin whole slide images for preclinical safety assessment. We trained a shallow CNN for segmenting marrow, 2 Mask R-CNN m
Externí odkaz:
https://doaj.org/article/1b442b94eac54cee9acfcbaf9141c60f
Autor:
WeiYu Lin, Daqi Xu, Cary D. Austin, Patrick Caplazi, Kate Senger, Yonglian Sun, Surinder Jeet, Judy Young, Donnie Delarosa, Eric Suto, Zhiyu Huang, Juan Zhang, Donghong Yan, Cesar Corzo, Kai Barck, Sharmila Rajan, Carrie Looney, Vineela Gandham, Justin Lesch, Wei-Ching Liang, Elaine Mai, Hai Ngu, Navneet Ratti, Yongmei Chen, Dinah Misner, Tori Lin, Dimitry Danilenko, Paula Katavolos, Estelle Doudemont, Hirdesh Uppal, Jeffrey Eastham, Judy Mak, Patricia E. de Almeida, Katherine Bao, Azadeh Hadadianpour, Mary Keir, Richard A. D. Carano, Lauri Diehl, Min Xu, Yan Wu, Robby M. Weimer, Jason DeVoss, Wyne P. Lee, Mercedesz Balazs, Kevin Walsh, Kathila R. Alatsis, Flavius Martin, Ali A. Zarrin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Colony-stimulating factor 1 (CSF1) and interleukin 34 (IL34) signal via the CSF1 receptor to regulate macrophage differentiation. Studies in IL34- or CSF1-deficient mice have revealed that IL34 function is limited to the central nervous system and sk
Externí odkaz:
https://doaj.org/article/f5bbd900f7f94b86b15fbd853c8ad352
Autor:
Jennifer Vogt, Daniel Sheinson, Paula Katavolos, Hiroko Irimagawa, Min Tseng, Kathila R Alatsis, William R Proctor
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220406 (2019)
Micro-RNA (miR)-122 is a promising exploratory biomarker for detecting liver injury in preclinical and clinical studies. Elevations in serum or plasma have been associated with viral and autoimmune hepatitis, non-alcoholic steatohepatitis (NASH), hep
Externí odkaz:
https://doaj.org/article/b31bb7776a3c4e02b7e2eec23f309d96
Autor:
Joshua M. Baughman, Christopher M. Rose, Ganesh Kolumam, Joshua D. Webster, Emily M. Wilkerson, Anna E. Merrill, Timothy W. Rhoads, Rajkumar Noubade, Paula Katavolos, Justin Lesch, Donald S. Stapleton, Mary E. Rabaglia, Kathy L. Schueler, Raymond Asuncion, Melanie Domeyer, Jose Zavala-Solorio, Michael Reich, Jason DeVoss, Mark P. Keller, Alan D. Attie, Alexander S. Hebert, Michael S. Westphall, Joshua J. Coon, Donald S. Kirkpatrick, Anwesha Dey
Publikováno v:
Cell Reports, Vol 16, Iss 2, Pp 583-595 (2016)
We introduce neutron-encoded (NeuCode) amino acid labeling of mice as a strategy for multiplexed proteomic analysis in vivo. Using NeuCode, we characterize an inducible knockout mouse model of Bap1, a tumor suppressor and deubiquitinase whose in vivo
Externí odkaz:
https://doaj.org/article/8cdbcd1118fe43d0a32e0e75203ce3e3
Autor:
Sam R. Telford, Philip M. Armstrong, Paula Katavolos, Ivo Foppa, A. Sonia Olmeda Garcia, Mark L. Wilson, Andrew Spielman
Publikováno v:
Emerging Infectious Diseases, Vol 3, Iss 2, Pp 165-170 (1997)
To determine if eastern North American Ixodes dammini, like related ticks in Eurasia, maintain tick-borne encephalitis group viruses, we analyzed ticks collected from sites where the agent of Lyme disease is zoonotic. Two viral isolates were obtained
Externí odkaz:
https://doaj.org/article/fc8b248af51449d397baa1ba525e6f66
Autor:
Oliver Poetz, Thomas O. Joos, Andreas E. Steinhilber, Paula Katavolos, Cornelia Sommersdorf, Hannes Planatscher, Montserrat Carrasco-Triguero, Viktoria Anselm
Publikováno v:
Journal of Proteome Research. 20:4985-4994
Macrophage colony stimulating factor 1 receptor (MCSF1R), osteopontin (OPN), high-mobility group protein B1 (HMGB1), glutamate dehydrogenase (GLDH), keratin 18 (K18), and caspase-cleaved keratin 18 (ccK18) are considered promising mechanistic biomark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb798a5007f49bfd04ddcaa3068b64f3
https://doi.org/10.1021/acs.jproteome.1c00478
https://doi.org/10.1021/acs.jproteome.1c00478
Autor:
Roxanne Andaya, F. Anthony Romero, Paula Katavolos, Anand Kumar Katakam, Edna F. Choo, Gary Cain, Steven Magnuson, Jonathan Maher, Cindy Farman, Justin Ly
Publikováno v:
Toxicologic Pathology. 48:465-480
Cyclic adenosine monophosphate-response element (CREB)-binding protein (CBP) and EP300E1A-binding protein (p300) are members of the bromodomain and extraterminal motif (BET) family. These highly homologous proteins have a key role in modulating trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c290f02af0cd42a80474a188284c6b4f
https://doi.org/10.1177/0192623319898469
https://doi.org/10.1177/0192623319898469
Autor:
Anne Provencher, Paula Katavolos
Publikováno v:
Toxicologic pathology. 49(8)
This symposium synopsis summarizes key points discussed related to clinical pathology data interpretation for reproduction and juvenile toxicology studies. In pregnant and growing animals, several changes in clinical pathology parameters linked to gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a66c5b05497a1f0944ea8f4ac9db355
https://pubmed.ncbi.nlm.nih.gov/34431401
https://pubmed.ncbi.nlm.nih.gov/34431401
Autor:
Dewakar, Sangaraju, Paula, Katavolos, Xiaorong, Liang, Carolina, Chou, Tanja S, Zabka, Brian, Dean, Jonathan, Maher
Publikováno v:
Toxicology and Applied Pharmacology. 443:116008
The use of bile acids as functional biomarkers for hepatobiliary injury and disease has been proposed for decades, but the utility has been generally limited due to lack of sensitivity in diagnosis and assay availability. However, recent advances in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185c749419c3043cde6432a99b165edd
https://doi.org/10.1016/j.taap.2022.116008
https://doi.org/10.1016/j.taap.2022.116008
Autor:
Paula Katavolos, Albert E. Schultze, Jennifer B. Pierson, Marjory B. Brooks, Alan Y. Chiang, Michael K. Pugsley, Cindy E. Fishman, Stanley T. Parish
Publikováno v:
Journal of pharmacological and toxicological methods. 107
Introduction: Zucker diabetic fatty (ZDF) rats are used widely as an animal model of metabolic syndrome and insulin resistance. Our study focused on the effects of high versus low dietary fat on the development of Type 2 diabetes in obese male ZDF ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9485b351d8154f61efaf366e6d85d1
https://pubmed.ncbi.nlm.nih.gov/33122074
https://pubmed.ncbi.nlm.nih.gov/33122074