Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Paula J. Foster"'
Autor:
Sydney Relouw, George J. Dugbartey, Patrick McLeod, Natasha N. Knier, Francisco Martinez Santiesteban, Paula J. Foster, Heather-Anne Cadieux-Pitre, Nicole M. Hague, Jenna Caine, Kaitlin Belletti, Sally Major, Caroline O’Neil, Manal Y. Gabril, Madeleine Moussa, Melissa J. Huynh, S.M. Mansour Haeryfar, Alp Sener
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1212 (2024)
Present bladder cancer therapies have relatively limited therapeutic impact and account for one of the highest lifetime treatment costs per patient. Therefore, there is an urgent need to explore novel and optimized treatment strategies. The present s
Externí odkaz:
https://doaj.org/article/cdbebf895e8a4a71b61116e9361ba8c3
Autor:
Corby Fink, Julia J. Gevaert, John W. Barrett, Jimmy D. Dikeakos, Paula J. Foster, Gregory A. Dekaban
Publikováno v:
European Radiology Experimental, Vol 7, Iss 1, Pp 1-17 (2023)
Abstract Background Despite widespread study of dendritic cell (DC)-based cancer immunotherapies, the in vivo postinjection fate of DC remains largely unknown. Due in part to a lack of quantifiable imaging modalities, this is troubling as the amount
Externí odkaz:
https://doaj.org/article/1efb13964c7743ad84a46c760b57440c
Autor:
Ryan J. Williams, Olivia C. Sehl, Julia J. Gevaert, Shirley Liu, John J. Kelly, Paula J. Foster, John A. Ronald
Publikováno v:
Tomography, Vol 9, Iss 1, Pp 178-194 (2023)
Magnetic particle imaging (MPI) provides hotspot tracking and direct quantification of superparamagnetic iron oxide nanoparticle (SPIO)-labelled cells. Bioluminescence imaging (BLI) with the luciferase reporter gene Akaluc can provide complementary i
Externí odkaz:
https://doaj.org/article/0cfef28ed4874c5a9bf9f0ed85783eab
Autor:
Sawyer Rhae Badiuk, Jonathan D. Thiessen, Saman Maleki Vareki, Paula J. Foster, Jeff Z. Chen, Eugene Wong
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 21, Iss , Pp 115-122 (2022)
Brain metastases affect more breast cancer patients than ever before due to increased overall patient survival with improved molecularly targeted treatments. Approximately 25–34% of breast cancer patients develop brain metastases in their lifetime.
Externí odkaz:
https://doaj.org/article/6692c864799246678c0a472382979905
Autor:
Olivia C. Sehl, Paula J. Foster
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Magnetic particle imaging (MPI) and fluorine-19 (19F) MRI produce images which allow for quantification of labeled cells. MPI is an emerging instrument for cell tracking, which is expected to have superior sensitivity compared to 19F MRI. Ou
Externí odkaz:
https://doaj.org/article/5b499c4bc47e4890b6d7cc4b1ee8a021
Autor:
Patrick T. Rudak, Joshua Choi, Katie M. Parkins, Kelly L. Summers, Dwayne N. Jackson, Paula J. Foster, Anton I. Skaro, Ken Leslie, Vivian C. McAlister, Vijay K. Kuchroo, Wataru Inoue, Olivier Lantz, S.M. Mansour Haeryfar
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108979- (2021)
Summary: The deleterious effects of psychological stress on mainstream T lymphocytes are well documented. However, how stress impacts innate-like T cells is unclear. We report that long-term stress surprisingly abrogates both T helper 1 (TH1)- and TH
Externí odkaz:
https://doaj.org/article/6b28ec3ee5014eb1b4081f330d2f952d
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 667 (2022)
Breast cancer remains a leading cause of mortality among women worldwide. Brain metastases confer extremely poor prognosis due to a lack of understanding of their specific biology, unique physiologic and anatomic features of the brain, and limited tr
Externí odkaz:
https://doaj.org/article/63086142b3d54bda9a687a0389fc85b4
Autor:
Niloufar Zarghami, Donna H. Murrell, Michael D. Jensen, Frederick A. Dick, Ann F. Chambers, Paula J. Foster, Eugene Wong
Publikováno v:
Radiation Oncology, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract Background Brain metastasis is becoming increasingly prevalent in breast cancer due to improved extra-cranial disease control. With emerging availability of modern image-guided radiation platforms, mouse models of brain metastases and small
Externí odkaz:
https://doaj.org/article/fdb6e5473117484daf7628971ef8cbef
Autor:
Donna H. Murrell, Niloufar Zarghami, Michael D. Jensen, Ann F. Chambers, Eugene Wong, Paula J. Foster
Publikováno v:
Translational Oncology, Vol 9, Iss 3, Pp 219-227 (2016)
INTRODUCTION: The incidence of brain metastasis due to breast cancer is increasing, and prognosis is poor. Treatment is challenging because the blood-brain barrier (BBB) limits efficacy of systemic therapies. In this work, we develop a clinically rel
Externí odkaz:
https://doaj.org/article/e5afc095936942559353c1f4327848a6
Autor:
Donna H. Murrell, Amanda M. Hamilton, Christiane L. Mallett, Robbert van Gorkum, Ann F. Chambers, Paula J. Foster
Publikováno v:
Translational Oncology, Vol 8, Iss 3, Pp 176-184 (2015)
OBJECTIVES: Brain metastases due to breast cancer are increasing, and the prognosis is poor. Lack of effective therapy is attributed to heterogeneity of breast cancers and their resulting metastases, as well as impermeability of the blood–brain bar
Externí odkaz:
https://doaj.org/article/0c2250707af24455b39ae05035aef3a3