Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Paula J. Brunton"'
Autor:
Alice Sanson, Paula Krieg, Milena M. Schramm, Kerstin Kellner, Rodrigue Maloumby, Stefanie M. Klampfl, Paula J. Brunton, Oliver J. Bosch
Publikováno v:
Neurobiology of Stress, Vol 30, Iss , Pp 100631- (2024)
To ensure the unrestricted expression of maternal behaviour peripartum, activity of the corticotropin-releasing factor (CRF) system needs to be minimised. CRF binding protein (CRF-BP) might be crucial for this adaptation, as its primary function is t
Externí odkaz:
https://doaj.org/article/e7034aeb40a64d9cae8eb9ff82a787da
Autor:
Laura C. Graham, Samantha L. Eaton, Paula J. Brunton, Abdelmadjid Atrih, Colin Smith, Douglas J. Lamont, Thomas H. Gillingwater, Giuseppa Pennetta, Paul Skehel, Thomas M. Wishart
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2017)
Abstract Background Neurons are highly polarized cells consisting of three distinct functional domains: the cell body (and associated dendrites), the axon and the synapse. Previously, it was believed that the clinical phenotypes of neurodegenerative
Externí odkaz:
https://doaj.org/article/0e5d6236a27f4b718ca0a780e7bcc4c4
Publikováno v:
Sze, Y, Fernandes, J, Kolodziejczyk, Z & Brunton, P 2022, ' Maternal glucocorticoids do not directly mediate the effects of maternal social stress on the fetus ', Journal of Endocrinology, vol. 255, no. 3, pp. 143-158 . https://doi.org/10.1530/JOE-22-0226
Stress during pregnancy negatively affects the fetus and increases the risk for affective disorders in adulthood. Excess maternal glucocorticoids are thought to mediate fetal programming; however, whether they exert their effects directly or indirect
Autor:
Paula J. Brunton, Ying Sze
Publikováno v:
Sze, Y & Brunton, P 2020, ' Sex, stress and steroids ', European Journal of Neuroscience, vol. 52, no. 1 . https://doi.org/10.1111/ejn.14615
The hypothalamo-pituitary-adrenal (HPA) axis plays a key role in the neuroendocrine response to stress and in maintaining physiological homoeostasis. However, stress that is chronic in nature can lead to HPA axis dysfunction and increase the risk for
Autor:
Ying Sze, Paula J. Brunton
Publikováno v:
Sze, Y & Brunton, P 2022, ' Neurosteroids and early-life programming: An updated perspective ', Current Opinion in Endocrine and Metabolic Research, vol. 25, 100367 . https://doi.org/10.1016/j.coemr.2022.100367
Early-life stress can lead to detrimental offspring outcomes, including an increased risk for mood disorders and hypothalamic-pituitary-adrenal axis dysregulation. Neurosteroids bind to ligand-gated neurotransmitter receptors, rapidly modulating neur
Autor:
Paula J. Brunton
Publikováno v:
Brunton, P 2019, ' Endogenous opioid signalling in the brain during pregnancy and lactation ', Cell and tissue research, vol. 375, no. 1, pp. 69-83 . https://doi.org/10.1007/s00441-018-2948-1
During pregnancy, the regulation of several neuroendocrine systems is altered to support the pregnancy and facilitate the transition to motherhood. These adaptations are organised by the mother's brain and include those that serve to optimise foetal
Autor:
Paula J. Brunton, David R. Grattan
Adaptations to maternal physiology are required for a successful pregnancy outcome. These changes are primarily orchestrated by the mother's brain and involve multiple neuroendocrine systems. For this book, the editors have gathered internationally r
Autor:
Hannah Scott, Alessio Alfieri, Paula J. Brunton, Mark F. Rogers, C. P. Case, Thomas J. Phillips, V. Volpato, Ying Sze
Publikováno v:
Scott, H, Phillips, T, Sze, Y, Alfieri, A, Rogers, M, Volpato, V, Case, P & Brunton, P 2020, ' Maternal antioxidant treatment prevents the adverse effects of prenatal stress on the offspring’s brain and behavior ', Neurobiology of Stress, vol. 13, pp. 100281 . https://doi.org/10.1016/j.ynstr.2020.100281
Neurobiology of Stress
Neurobiology of Stress, Vol 13, Iss, Pp 100281-(2020)
Neurobiology of Stress
Neurobiology of Stress, Vol 13, Iss, Pp 100281-(2020)
Maternal exposure to stress during pregnancy is associated with an increased risk of psychiatric disorders in the offspring in later life. The mechanisms through which the effects of maternal stress are transmitted to the fetus are unclear, however t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01f590c3059b68cd4b50e5b3d5f6781
https://hdl.handle.net/20.500.11820/24806ff4-7485-4533-a4fb-1c874ef04b99
https://hdl.handle.net/20.500.11820/24806ff4-7485-4533-a4fb-1c874ef04b99
Autor:
Paula J. Brunton, Ying Sze
Publikováno v:
Journal of Neuroendocrinology
Sze, Y & Brunton, P 2020, ' Effects of prenatal stress on neuroactive steroid responses to acute stress in adult male and female rats ', Journal of Neuroendocrinology . https://doi.org/10.1111/jne.12916
J Neuroendocrinol
Sze, Y & Brunton, P 2020, ' Effects of prenatal stress on neuroactive steroid responses to acute stress in adult male and female rats ', Journal of Neuroendocrinology . https://doi.org/10.1111/jne.12916
J Neuroendocrinol
Acute swim stress results in the robust production of several neuroactive steroids, which act as mediators of the stress response. These steroids include glucocorticoids, and positive GABAA receptor modulatory steroids such as allopregnanolone and te