Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Paula J. Bartlett"'
Autor:
Juliana C. Corrêa-Velloso, Paula J. Bartlett, Robert Brumer, Lawrence D. Gaspers, Henning Ulrich, Andrew P. Thomas
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103139- (2021)
Summary: Extracellular agonists linked to inositol-1,4,5-trisphosphate (IP3) formation elicit cytosolic Ca2+ oscillations in many cell types, but despite a common signaling pathway, distinct agonist-specific Ca2+ spike patterns are observed. Using qP
Externí odkaz:
https://doaj.org/article/dcf883fb2f314a749c6a1a22f4d13dea
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: Ca2+ oscillations that depend on inositol-1,4,5-trisphosphate (IP3) have been ascribed to biphasic Ca2+ regulation of the IP3 receptor (IP3R) or feedback mechanisms controlling IP3 levels in different cell types. IP3 uncaging in hepatocytes
Externí odkaz:
https://doaj.org/article/2d1b25963461437bafc2ba97b1a7269f
Autor:
Lawrence D. Gaspers, Paula J. Bartlett, Antonio Politi, Paul Burnett, Walson Metzger, Jane Johnston, Suresh K. Joseph, Thomas Höfer, Andrew P. Thomas
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1209-1218 (2014)
Receptor-mediated oscillations in cytosolic Ca2+ concentration ([Ca2+]i) could originate either directly from an autonomous Ca2+ feedback oscillator at the inositol 1,4,5-trisphosphate (IP3) receptor or as a secondary consequence of IP3 oscillations
Externí odkaz:
https://doaj.org/article/a06c5cf23af84f0089b0d8c84973e322
Autor:
Robert P. Brumer, Juliana C. Corrêa‐Velloso, Samantha J. Thomas, Oleta A. Sandiford, Andrew P. Thomas, Paula J. Bartlett
Publikováno v:
The Journal of Physiology. 601:1383-1405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f3f2c42af3da461e609b9a1f523971f
https://doi.org/10.1113/jp283691
https://doi.org/10.1113/jp283691
Autor:
Robert P. Brumer, Juliana C. Corrêa-Velloso, Samantha J. Thomas, Oleta A. Sandiford, Andrew P. Thomas, Paula J. Bartlett
Excess consumption of carbohydrates, fat, and calories leads to non-alcoholic fatty liver disease (NAFLD) and hepatic insulin resistance; major factors in the pathogenesis of type II diabetes. Hormones and catecholamines acting through G-protein coup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a53d70985b694ea2e97415d89a5d363
https://doi.org/10.1101/2022.08.28.505514
https://doi.org/10.1101/2022.08.28.505514
Autor:
Aline de Lima Leite, Kely Braga Imamura, Adelino Vieira de Godoy Netto, Daphne D. L. Teodoro, Stela Virgilio, Luiz R. O. Tosi, Angela Maria Arenas Velásquez, Jecika M. Velasques, Thais Gaban Passalacqua, Marcia A. S. Graminha, Andrew P. Thomas, Paula J. Bartlett, Irwin Alexander Patiño Linares, Marília Afonso Rabelo Buzalaf
Publikováno v:
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Antimicrob Agents Chemother
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Antimicrob Agents Chemother
Other grants supported: Programa de Apoio ao Desenvolvimento Científico da Faculdade de Ciências Farmacêuticas da UNESP (PADC); and funding from the Thomas P. Infusino Endowment at Rutgers University. This study was financed in part by the Coorden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32804c6b26eea78067d4bd38ae1ca8a3
https://doi.org/10.1128/aac.00767-21
https://doi.org/10.1128/aac.00767-21
Autor:
Juliana C, Corrêa-Velloso, Paula J, Bartlett, Robert, Brumer, Lawrence D, Gaspers, Henning, Ulrich, Andrew P, Thomas
Publikováno v:
iScience
Summary Extracellular agonists linked to inositol-1,4,5-trisphosphate (IP3) formation elicit cytosolic Ca2+ oscillations in many cell types, but despite a common signaling pathway, distinct agonist-specific Ca2+ spike patterns are observed. Using qPC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce0e56f672f0611fbe4761d3bafcbec4
https://pubmed.ncbi.nlm.nih.gov/34646983
https://pubmed.ncbi.nlm.nih.gov/34646983
Autor:
Jecika M. Velasques, Adelino Vieira de Godoy Netto, Daphne D. L. Teodoro, Stela Virgilio, Aline de Lima Leite, Paula J. Bartlett, Irwin Alexander Patiño Linares, Marília Afonso Rabelo Buzalaf, Marcia A. S. Graminha, Thais Gaban Passalacqua, Angela Maria Arenas Velásquez, Luiz R. O. Tosi, Andrew P. Thomas, Kely Braga Imamura
Publikováno v:
SSRN Electronic Journal.
Background: Leishmaniasis is a parasitic disease that affects millions of people and lacks new molecules for treatment. The current treatment is associated with high toxicity, a difficult administration route, and the emergence of resistant strains.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd7275158d88181f20812a060520bc68
https://doi.org/10.2139/ssrn.3814788
https://doi.org/10.2139/ssrn.3814788
Publikováno v:
Function (Oxford, England). 2(2)
Receptor-coupled phospholipase C (PLC) is an important target for the actions of ethanol. In the ex vivo perfused rat liver, concentrations of ethanol >100 mM were required to induce a rise in cytosolic calcium (Ca2+) suggesting that these responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c68497007817386466553b4e862ba5a
https://pubmed.ncbi.nlm.nih.gov/35330811
https://pubmed.ncbi.nlm.nih.gov/35330811
Autor:
James Sneyd, Paula J. Bartlett, Juliana C. Corrêa-Velloso, Andrew P. Thomas, Vivien Kirk, Ielyaas Cloete
Publikováno v:
Journal of theoretical biology. 518
Calcium (Ca2+) oscillations in hepatocytes have a wide dynamic range. In particular, recent experimental evidence shows that agonist stimulation of the P2Y family of receptors leads to qualitatively diverse Ca2+ oscillations. We present a new model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31f1f22038b8f72dc164dbbda7cc964
https://pubmed.ncbi.nlm.nih.gov/33607144
https://pubmed.ncbi.nlm.nih.gov/33607144