Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Paula J, Valentine"'
Autor:
Janet A. Jackson, Simon T. Barry, Sandra R. Brave, Sharon Barnett, Graham Richmond, Lee Cooper, Neil H. James, Neil R. Smith, Jane Kendrew, Stephen R. Wedge, Paula J. Valentine, Taylor Sian Tomiko, Michael D. Walker, Sarah J. Boffey, Sarah Beck, Laurent Francois Andre Hennequin, Lyndsey L. Kilburn, Rosemary Chester, Peter F. Wadsworth, Alison L. Bigley, Juliane M. Jürgensmeier, Donald J. Ogilvie, Jon Curwen, Michael Dukes
Publikováno v:
Cancer research. 65(10)
Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a promising therapeutic approach that aims to stabilize the progression of solid malignancies by abrogating tumor-induced angiogenesis. This may be accomplished by inhibiting the
Autor:
Stephen R, Wedge, Donald J, Ogilvie, Michael, Dukes, Jane, Kendrew, Rosemary, Chester, Janet A, Jackson, Sarah J, Boffey, Paula J, Valentine, Jon O, Curwen, Helen L, Musgrove, George A, Graham, Gareth D, Hughes, Andrew P, Thomas, Elaine S E, Stokes, Brenda, Curry, Graham H P, Richmond, Peter F, Wadsworth, Alison L, Bigley, Laurent F, Hennequin
Publikováno v:
Cancer research. 62(16)
ZD6474 [N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine]is a potent, p.o. active, low molecular weight inhibitor of kinase insert domain-containing receptor [KDR/vascular endothelial growth factor receptor (
Autor:
Rajesh Odedra, Juliane M. Jürgensmeier, Anderson J. Ryan, Paul D. Smith, Philippa Wood, Stephen R. Wedge, Donald J. Ogilvie, Robert W. Wilkinson, Paula J. Valentine, Armelle Logie, Sharon Barnett, Jane Kendrew, Paul Elvin
Publikováno v:
Cancer Research. 70:1372-1372
Cediranib (RECENTIN™) is a highly potent vascular endothelial growth factor (VEGF) signaling inhibitor of all three VEGF receptors that is suitable for once-daily oral dosing. Cediranib is currently in Phase III development in first-line colorectal
Autor:
Stephen R. Wedge, Jane Kendrew, S. Barnett, Paula J. Valentine, Laurent Francois Andre Hennequin, Juliane M. Jürgensmeier, Donald J. Ogilvie, Sandra R. Brave
Publikováno v:
European Journal of Cancer Supplements. 2:52