Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paula J, Davidson"'
Autor:
Richard Axtell, Sanjeet Rangarajan, Dawna Dylewski, David Cherba, Deanna Mitchell, Sean Vance, Craig P. Webb, Stephanie B. Scott, Eric Lester, Emily Eugster, Paula J. Davidson, Noel R. Monks, Joseph J. Junewick, Nicole L. Beuschel, Patrick J. Richardson, David J. Monsma
Publikováno v:
Pediatric Blood & Cancer. 61:1570-1577
Background Precision (Personalized) medicine has the potential to revolutionize patient health care especially for many cancers where the fundamental disease etiology remains either elusive or has no available therapy. Here we outline a study in alve
Publikováno v:
Journal of Cardiac Failure. 24:S128
Introduction Use of CFLVADs as a BTT continues to increase. The mechanisms of host immune system activation following implantation leading to allosensitization complicating transplantation outcomes are not well understood. Hypothesis We hypothesize t
Publikováno v:
Connective Tissue Research. 51:230-239
Matrix metalloproteinases (MMP)-13 activity is necessary for normal skeletal development and plays a central role in cartilage degeneration associated with osteoarthritis (OA). The studies we described here examine the interactions of the hemopexin d
Autor:
Greg Cavey, Gary Gibson, William W. Cole, Liang Zhang, Chiyang Yu, Bingbing Zhang, Xinli Wang, Maozhou Yang, Paula J. Davidson
Publikováno v:
Journal of Chromatography B. 875:493-501
Like other members of the transforming growth factor beta (TGF-beta) family of growth factors, the biological activity of TGF-beta2 is believed to be regulated by the formation and dissociation of multiprotein complexes. To isolate the molecular comp
Autor:
David J, Monsma, David M, Cherba, Patrick J, Richardson, Sean, Vance, Sanjeet, Rangarajan, Dawna, Dylewski, Emily, Eugster, Stephanie B, Scott, Nicole L, Beuschel, Paula J, Davidson, Richard, Axtell, Deanna, Mitchell, Eric P, Lester, Joseph J, Junewick, Craig P, Webb, Noel R, Monks
Publikováno v:
Pediatric bloodcancer. 61(9)
Precision (Personalized) medicine has the potential to revolutionize patient health care especially for many cancers where the fundamental disease etiology remains either elusive or has no available therapy. Here we outline a study in alveolar rhabdo
Autor:
Andrew Borgman, Ting-Tung Chang, David J. Monsma, Anderson Peck, Noel R. Monks, Nathan J. Lanning, Chelsea A. Peterson, Brian J. Nickoloff, Paula J. Davidson, Pimiento Jose, Mackeigan P. Jeff
Publikováno v:
Molecular Cancer Research. 12:A37-A37
The notoriously high glucose uptake by metastatic melanoma (MM) lesions is commonly exploited clinically using PET/CT imaging to evaluate disease progression and treatment. The purpose of this study was to use patient-derived xenograft (PDX) MM model
Autor:
Dawna Dylewski, David J. Monsma, Jessica Foley, Donald J. Scholten, Paula J. Davidson, Matthew R. Steensma, Noel R. Monks
Publikováno v:
Cancer Research. 74:A70-A70
Introduction: Tumor-initiating cells (TICs) are a subpopulation of therapy resistant cells in osteosarcoma. To date, TICs have been experimentally defined based on the chosen isolation technique. Common to all isolation methods, TICs demonstrate a hi
Autor:
Mariaelena Pierobon, Paula J. Davidson, David J. Monsma, Alexander E. Ivliev, Brian J. Nickoloff, Andrew Borgman, Yuri Nikolsky, Marina Bessarabova, Noel R. Monks, Dawna Dylewski, Mary E. Winn, Valerie S. Calvert, Chelsea A. Peterson, David Cherba, Emanuel F. Petricoin, Emily Eugster, Craig P. Webb, Jose M. Pimiento
Publikováno v:
Molecular Cancer Therapeutics. 12:B12-B12
Development of resistance is a significant clinical problem for virtually all targeted cancer therapies. We have generated a reproducible, patient derived xenograft (PDX) model of acquired vemurafenib resistance to address these challenges. Continuou
Autor:
Emily Eugster, Tom Mikkelsen, Marie R. Mooney, Ana C. deCarvalho, Dylewski Dawna, Craig P. Webb, Anthony P. Popkie, Paula J. Davidson, Stephanie B. Scott, David J. Monsma, Noel R. Monks
Publikováno v:
Cancer Research. 72:4027-4027
Glioblastoma multiforme (GBM) is the most prevalent form of primary brain cancer in adults. Cancer stem cells (CSCs) are thought to drive the growth and metastasis of tumors, and are readily isolated from GBM patient tumors. These GBM CSCs are mainta
Autor:
Karl Dykema, Mary E. Winn, Dawna Dylewski, Jessica Foley, Donald J. Scholten, Matthew R. Steensma, David Cherba, Paula J. Davidson, Noel R. Monks, David J. Monsma
Publikováno v:
Journal of Translational Medicine
Background Osteosarcoma (OS) is the most common type of solid bone cancer, with latent metastasis being a typical mode of disease progression and a major contributor to poor prognosis. For this to occur, cells must resist anoikis and be able to recap