Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Paula I, van Noort"'
Autor:
Gerald W. Verhaegh, Jack A. Schalken, Roel Q.J. Schaapveld, Iman Schultz, Paula I. van Noort, Frank P. Smit, Cornelius F. Jansen, Onno van Hooij, Jasmijn G.M. van Kampen
The supplementary figures file contains additional data that are not provided in the main text (because of space constraints). Fig. S1, Data on the miR-520f expression models, incl. phase-contrast images; Fig. S2, Schematic representation of SOEing P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa9f61a709cee134bb2f33c6ef66539
https://doi.org/10.1158/0008-5472.22415786.v1
https://doi.org/10.1158/0008-5472.22415786.v1
Autor:
Gerald W. Verhaegh, Jack A. Schalken, Roel Q.J. Schaapveld, Iman Schultz, Paula I. van Noort, Frank P. Smit, Cornelius F. Jansen, Onno van Hooij, Jasmijn G.M. van Kampen
The supplementary materials and methods file contains a more detailed description of methods (cell culture, real-time and stem loop RT-PCR, Western blot analysis, and 3'-UTR reporter assays) that are described in the main text in brief. Methods that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac32e3991c2ce66354561fe5f392a9d1
https://doi.org/10.1158/0008-5472.22415780.v1
https://doi.org/10.1158/0008-5472.22415780.v1
Autor:
Gerald W. Verhaegh, Jack A. Schalken, Roel Q.J. Schaapveld, Iman Schultz, Paula I. van Noort, Frank P. Smit, Cornelius F. Jansen, Onno van Hooij, Jasmijn G.M. van Kampen
The supplementary table file contains a table with the names and origin of the cell lines used in this study (Suppl. Table S1). It also contains four tables with nucleotide sequences of primers and oligonucleotides used for qPCR and DNA sequence anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3eb928e439a78f85fee692e9adeda2
https://doi.org/10.1158/0008-5472.22415783.v1
https://doi.org/10.1158/0008-5472.22415783.v1
Autor:
Jos B Poell, Rick J van Haastert, Thijs de Gunst, Iman J Schultz, Willemijn M Gommans, Mark Verheul, Francesco Cerisoli, Andre A F L van Puijenbroek, Paula I van Noort, Gregoire P Prevost, Roel Q J Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE, Vol 8, Iss 1 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0043569.].
Externí odkaz:
https://doaj.org/article/809690cb2b36494aae39d53295789ec4
Autor:
Jos B Poell, Rick J van Haastert, Thijs de Gunst, Iman J Schultz, Willemijn M Gommans, Mark Verheul, Francesco Cerisoli, Andre A F L van Puijenbroek, Paula I van Noort, Gregoire P Prevost, Roel Q J Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Externí odkaz:
https://doaj.org/article/d40c736567e848e5920930dd9625597e
Autor:
Frank Smit, Iman J. Schultz, Jasmijn G. M. van Kampen, Cornelius F.J. Jansen, Gerald W. Verhaegh, Paula I. van Noort, Jack A. Schalken, Roel Q.J. Schaapveld, Onno van Hooij
Publikováno v:
Cancer Research, 77, 2008-2017
Cancer Research, 77, 8, pp. 2008-2017
Cancer Research, 77, 8, pp. 2008-2017
Contains fulltext : 174182.pdf (Publisher’s version ) (Closed access) Reversing epithelial-to-mesenchymal transition (EMT) in cancer cells has been widely considered as an approach to combat cancer progression and therapeutic resistance, but a limi
Autor:
Jos B. Poell, Rick J. van Haastert, Thijs de Gunst, Iman J. Schultz, Willemijn M. Gommans, Mark Verheul, Francesco Cerisoli, Andre A.F.L. van Puijenbroek, Paula I. van Noort, Gregoire P. Prevost, Roel Q. J. Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1 (2013)
PLoS ONE, Vol 8, Iss 1 (2013)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Autor:
Jasmijn G M, van Kampen, Onno, van Hooij, Cornelius F, Jansen, Frank P, Smit, Paula I, van Noort, Iman, Schultz, Roel Q J, Schaapveld, Jack A, Schalken, Gerald W, Verhaegh
Publikováno v:
Cancer research. 77(8)
Reversing epithelial-to-mesenchymal transition (EMT) in cancer cells has been widely considered as an approach to combat cancer progression and therapeutic resistance, but a limited number of broadly comprehensive investigations of miRNAs involved in
Autor:
Antonio Romero-Ruiz, Maria Manfredi-Lozano, Manuel Tena-Sempere, David Garcia-Galiano, Magda A. M. Krajnc-Franken, Leonor Pinilla, Paula I. van Noort, Dorette van Ingen Schenau, Víctor M. Navarro, Francisco Gaytan, Silvia Leon, Marion Blomenröhr
Publikováno v:
Endocrinology
Kisspeptins (Kp), products of the Kiss1 gene that act via Gpr54 to potently stimulate GnRH secretion, operate as mediators of other regulatory signals of the gonadotropic axis. Mouse models of Gpr54 and/or Kiss1 inactivation have been used to address
Autor:
Rogier C. Buijsman, Rachel Deborah Van Rijn, Arie Vesser, Paula I. van Noort, Willem G.E.J. Schoonen, Stan van Boeckel, Pedro H. H. Hermkens, Cor W. Kuil, Jan A. Gossen, Jan Gerard Sterrenburg, Jan Klomp, Thijs Stock, Gerben Rovers, Geert Verdonk, Rein Dijkema, Anja Garritsen
Publikováno v:
Medicinal Chemistry Research. 13:210-215
HTS has been executed with a luciferase reporter assay in CHO cells stably expressing an ERa/GCNF chimer. Confirmed hits could be optimized some 10 to 100 fold. Partial agonists identified during the hit optimization process behaved as antagonists in