Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Paula H. A. Ronkainen"'
Autor:
Paula H A Ronkainen, Eija Pöllänen, Timo Törmäkangas, Kristina Tiainen, Markku Koskenvuo, Jaakko Kaprio, Taina Rantanen, Sarianna Sipilä, Vuokko Kovanen
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1819 (2008)
BackgroundMuscle strength declines on average by one percent annually from midlife on. In postmenopausal women this decrement coincides with a rapid decline in estrogen production. The genetics underlying the effects of estrogen on skeletal muscle re
Externí odkaz:
https://doaj.org/article/8c85faed835f4ca288dbb474d8c759ca
Autor:
Konstantin A. Artemenko, Eija Pöllänen, Lars Larsson, Rizwan Qaisar, Guillaume Renaud, Markku Alen, Yvette Hedström, Sarianna Sipilä, Paula H. A. Ronkainen, Vuokko Kovanen, Jaakko Kaprio, Jonas Bergquist
Publikováno v:
The Journal of Physiology. 591:2333-2344
Ageing is associated with a decline in muscle mass and strength leading to increased physical dependency in old age. Postmenopausal women experience a greater decline than men of similar age in parallel with the decrease in female sex steroid hormone
Autor:
Markku Alen, Paula H. A. Ronkainen, Eija Pöllänen, Sarianna Sipilä, Vuokko Kovanen, Maarit Ahtiainen, Urho M. Kujala, Suvi Pulkkinen, Jaakko Kaprio
Publikováno v:
Menopause. 19:1329-1335
Objective: The aim of this study was to evaluate the possibility of preventing the metabolic health consequences of postmenopausal hypogonadism with the use of long-term hormone therapy (HT). Methods: We used a monozygotic co-twin control design incl
Autor:
Markku Alen, Sarianna Sipilä, Jaakko Kaprio, Jukka Puolakka, Maarit Ahtiainen, Paula H. A. Ronkainen, Eija Pöllänen, Vuokko Kovanen
Publikováno v:
AGE; Vol 34
A thorough understanding of the role of estrogens on aging-related muscle weakness is lacking. To clarify the molecular mechanisms underlying the effects of hormone replacement therapy (HRT) on skeletal muscle, we analyzed systemic protein and local
Autor:
Paula H. A. Ronkainen, Vuokko Kovanen, Markku Koskenvuo, Harri Suominen, Jukka Puolakka, Tuija M. Mikkola, Sulin Cheng, Carina Ankarberg-Lindgren, Ari Heinonen, Jaakko Kaprio, Markku Alen, Taina Rantanen, Sarianna Sipilä, Urho M. Kujala
Publikováno v:
Journal of Bone and Mineral Research. 26:546-552
Although postmenopausal hormone-replacement therapy (HRT) is known to prevent fractures, knowledge on the influence of long-term HRT on bone strength and its determinants other than areal bone mineral density is scarce. This study used a genetically
Autor:
Noorkoiv M, Taija Finni, Paula H. A. Ronkainen, Kovanen, Sarianna Sipilä, Markku Alen, Jaakko Kaprio, Eija Pöllänen
Publikováno v:
Muscle & Nerve
Muscle & Nerve; Vol 44
Muscle & Nerve; Vol 44
Introduction: Postmenopausal monozygotic twin pairs discordant for hormone replacement therapy (HRT) provide an advantageous study design controlling for genetic background for elucidating the relationships between aging, sex hormone levels, muscle s
Autor:
Markku Alen, Eija Pöllänen, Vuokko Kovanen, Reino Pitkänen, Urho M. Kujala, Jaakko Kaprio, Sarianna Sipilä, Jukka Puolakka, Paula H. A. Ronkainen
Publikováno v:
Aging Cell. 9:1098-1110
Summary Aging is accompanied by inexorable loss of muscle tissue. One of the underlying causes for this is the massive change in the hormonal milieu of the body. The role of a female sex steroid – estrogen – in these processes is frequently negle
Autor:
Paula H. A. Ronkainen, Satu O A Koskinen, Dennis R. Taaffe, Urho M. Kujala, Timo Törmäkangas, Eija Pöllänen, Sulin Cheng, Vuokko Kovanen, Timo Takala, Harri Suominen, Vidal Fey, Jukka Puolakka, Sarianna Sipilä
Publikováno v:
AGE
Pöllänen, E, Fey, V, Törmäkangas, T, Ronkainen, P H A, Taaffe, D R, Takala, T, Koskinen, S, Cheng, S, Puolakka, J, Kujala, U M, Suominen, H, Sipilä, S & Kovanen, V 2010, ' Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle ', Age, vol. 32, no. 3, pp. 347-363 . https://doi.org/10.1007/s11357-010-9140-1
AGE; Vol 32
Age
Pöllänen, E, Fey, V, Törmäkangas, T, Ronkainen, P H A, Taaffe, D R, Takala, T, Koskinen, S, Cheng, S, Puolakka, J, Kujala, U M, Suominen, H, Sipilä, S & Kovanen, V 2010, ' Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle ', Age, vol. 32, no. 3, pp. 347-363 . https://doi.org/10.1007/s11357-010-9140-1
AGE; Vol 32
Age
At the moment, there is no clear molecular explanation for the steeper decline in muscle performance after menopause or the mechanisms of counteractive treatments. The goal of this genome-wide study was to identify the genes and gene clusters through
Autor:
Paula H. A. Ronkainen, Jaakko Kaprio, Eeva-Maija Palonen, Jukka Puolakka, Markku Alen, Vuokko Kovanen, Urho M. Kujala, Carina Ankarberg-Lindgren, Eija Pöllänen, Sarianna Sipilä, Esa Hämäläinen, Ursula Turpeinen
Publikováno v:
Journal of Applied Physiology. 107:25-33
We investigated whether long-term hormone replacement therapy (HRT) is associated with mobility and lower limb muscle performance and composition in postmenopausal women. Fifteen 54- to 62-yr-old monozygotic female twin pairs discordant for HRT were
Autor:
Maija Vihinen-Ranta, Johanna P. Laakkonen, Markku S. Kulomaa, Einari A. Niskanen, Seppo Ylä-Herttuala, Paula H. A. Ronkainen, Minna U. Kaikkonen, Mirka Salminen, Teemu O. Ihalainen, Maija Häkkinen, Kari J. Airenne
Publikováno v:
Cellular Microbiology. 10:667-681
Baculovirus, Autographa californica multiple nucleopolyhedrovirus (AcMNPV), has the ability to transduce mammalian cell lines without replication. The general objective of this study was to detect the transcription and expression of viral immediate-e