Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paula Gonzalez-Figueroa"'
Autor:
Shlomo Elias, Rahul Sharma, Michael Schizas, Izabella Valdez, Sham Rampersaud, Sun-Mi Park, Paula Gonzalez-Figueroa, Quan-Zhen Li, Beatrice Hoyos, Alexander Y. Rudensky
Publikováno v:
Journal of Experimental Medicine. 219
Regulatory T (Treg) cells represent a specialized lineage of suppressive CD4+ T cells whose functionality is critically dependent on their ability to migrate to and dwell in the proximity of cells they control. Here we show that continuous expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba20b78fa37d4c5613475eb71636a80
https://doi.org/10.1084/jem.20220047
https://doi.org/10.1084/jem.20220047
Autor:
Alexander Y. Rudensky, Rahul Sharma, Shlomo Elias, Beatrice Hoyos, Izabella Valdez, Paula Gonzalez-Figueroa, Michael Schizas, Quan Zhen Li, Sun Mi Park
Regulatory T (Treg) cells represent a specialized lineage of suppressive CD4+ T cells, whose functionality is critically dependent on their ability to migrate to, and dwell in the proximity of cells they control. Here we show that continuous expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46127097ef95eb53dc4063225327b887
https://doi.org/10.1101/2021.11.14.468515
https://doi.org/10.1101/2021.11.14.468515
Autor:
Salvatore Valvo, Pablo F. Canete, Ilenia Papa, Michael Meyer-Hermann, David Saliba, Claudio Doglioni, Carola G. Vinuesa, Maurilio Ponzoni, Hayley A. McNamara, Michele A. Grimbaldeston, Paula Gonzalez-Figueroa, Rebecca A. Sweet, Ian A. Cockburn, Harpreet Vohra, Sonia Bustamante, Michael L. Dustin
Publikováno v:
Nature
Protective high-affinity antibody responses depend on competitive selection of B cells carrying somatically mutated B-cell receptors by follicular helper T (T FH ) cells in germinal centres. The rapid T-B-cell interactions that occur during this proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ad62707ec019496fd76fccbe3fdede
https://doi.org/10.1038/nature23013
https://doi.org/10.1038/nature23013
Autor:
Matthew C. Cook, Ismail Sayin, Holly A. Bolton, Michael Meyer-Hermann, Emma F Barry, Claudio Doglioni, Barbara Fazekas de St Groth, Katharine J. Bassett, Paula Gonzalez-Figueroa, Naganari Ohkura, Rebecca A. Sweet, Marta Cuenca, David H. Canaday, Pablo F. Canete, Jonathan A. Roco, Angel F. Lopez, Shimon Sakaguchi, Carola G. Vinuesa, Ilenia Papa
Publikováno v:
The Journal of Experimental Medicine
The Journal of experimental medicine
Journal of Experimental Medicine 216 (2019) 8, p. 1843-1856--The journal of experimental medicine--J. Exp. Med.--The journal of experimental medicine--0022-1007--1540-9538
The Journal of experimental medicine
Journal of Experimental Medicine 216 (2019) 8, p. 1843-1856--The journal of experimental medicine--J. Exp. Med.--The journal of experimental medicine--0022-1007--1540-9538
Uncontrolled IgE responses drive allergies and anaphylaxis. Here, Cañete et al. describe a human follicular regulatory T cell population that does not express FOXP3 and produces abundant IL-10, which limits IgE switching. These cells appear to be ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b178be86bcc21e247a66d67b2307eec6
https://pubmed.ncbi.nlm.nih.gov/31209070
https://pubmed.ncbi.nlm.nih.gov/31209070
Autor:
Carola G. Vinuesa, Paula Gonzalez-Figueroa, Jonathan A. Roco, Lorena Nunez Villacis, Ilenia Papa, Maurice Stanley, Michelle A. Linterman, Alexander L. Dent, Pablo F. Canete
Publikováno v:
Cell. 184:1775-1789.e19
Regulatory T cells prevent the emergence of autoantibodies and excessive IgE, but the precise mechanisms are unclear. Here, we show that BCL6-expressing Tregs, known as follicular regulatory T (Tfr) cells, produce abundant neuritin protein that targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee340dc8ccd0e83f6953b0c7cd9cc56a
https://doi.org/10.1016/j.cell.2021.02.027
https://doi.org/10.1016/j.cell.2021.02.027
Autor:
Gerardo López-Rodas, Angela L. Riffo-Campos, Paula Gonzalez-Figueroa, Gema Tur, M. Isabel Rodrigo, Josefa Castillo, Luis Franco, Elena I. Georgieva, José L. Rodríguez
Publikováno v:
Journal of Biological Chemistry. 290:197-208
Histone post-translational modifications and nucleosome remodeling are coordinate events involved in eukaryotic transcriptional regulation. There are relatively few data on the time course with which these events occur in individual nucleosomes. As a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7ec62fb55475acad84f1cf347f4156
https://doi.org/10.1074/jbc.m114.579292
https://doi.org/10.1074/jbc.m114.579292
Autor:
Kai-Michael Toellner, Michael Meyer-Hermann, Sebastian Binder, Jean Cappello, Harpreet Vohra, Julia I. Ellyard, Christian M. Nefzger, Jose M. Polo, Pablo F. Canete, Jonathan A. Roco, Luka Mesin, Carla R. Nowosad, Gabriel D. Victora, Ariën Schiepers, Paula Gonzalez-Figueroa, Philippe Robert, Qian Shen, Yang Zhang, Lynn M. Corcoran, Carola G. Vinuesa
Publikováno v:
Immunity
Class-switch recombination (CSR) is a DNA recombination process that replaces the immunoglobulin (Ig) constant region for the isotype that can best protect against the pathogen. Dysregulation of CSR can cause self-reactive BCRs and B cell lymphomas;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e6167f8cf4ce84013b04edc7affc0e
https://doi.org/10.1016/j.immuni.2019.07.001
https://doi.org/10.1016/j.immuni.2019.07.001
Publikováno v:
Trends in molecular medicine. 23(2)
Generating Tier 2 HIV neutralizing antibody (nAb) responses by immunization remains a challenging problem, and the immunological barriers to induction of such responses with Env immunogens remain unclear. Here, some rhesus monkeys developed autologou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ced0750012dd56b44e3f42bb1055d8
https://pubmed.ncbi.nlm.nih.gov/27880897
https://pubmed.ncbi.nlm.nih.gov/27880897
Autor:
Maarten A. Ligtenberg, Alvaro Lladser, Nicole Rojas-Colonelli, Jonathan A. Roco, Andrés A. Herrada, Paula Gonzalez-Figueroa, Cesar Oyarce
Publikováno v:
HUMAN VACCINES & IMMUNOTHERAPEUTICS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
DNA vaccines have emerged as an attractive strategy to promote protective cellular and humoral immunity against the encoded antigen. DNA vaccines are easy to generate, inexpensive to produce and purify at large-scale, highly stable and safe. In addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4bee9927b8fd3fdfc998703942a9fd