Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Paula González Alonso"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32575 (2012)
Mycobacterium cultures, from patients suspected of tuberculosis or nontuberculous mycobacteria (NTM) infection, need to be identified. It is most critical to identify cultures belonging to the Mycobacterium tuberculosis complex, but also important to
Externí odkaz:
https://doaj.org/article/dc4a427da3d640ac87f615175a662f55
Autor:
Federico Rojo, Juan Madoz-Gúrpide, Ana Rovira, Joan Albanell, Jesús García-Foncillas, Pilar Eroles, Ana Lluch, Rosario Perona, Carmen Cañadas, Ion Cristóbal, Ester Martín-Aparicio, Paula González-Alonso, Rebeca Manso, Cristina Chamizo, Sandra Zazo, Raúl Rincón
Supplementary Figure S1. MKP-1 protein abundance levels in MDA-MB-231 cells treated with docetaxel at progressively increasing times. Supplementary Figure S2. Cell growth in the presence of the docetaxel or doxorubicin of breast cancer cell lines ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f9f3360e9d15474b0bfdd5d4c07d6b
https://doi.org/10.1158/1535-7163.22506093
https://doi.org/10.1158/1535-7163.22506093
Autor:
Federico Rojo, Juan Madoz-Gúrpide, Ana Rovira, Joan Albanell, Jesús García-Foncillas, Pilar Eroles, Ana Lluch, Rosario Perona, Carmen Cañadas, Ion Cristóbal, Ester Martín-Aparicio, Paula González-Alonso, Rebeca Manso, Cristina Chamizo, Sandra Zazo, Raúl Rincón
MAPK phosphatase-1 (MKP-1) is overexpressed during malignant transformation of the breast in many patients, and it is usually associated with chemoresistance through interference with JNK-driven apoptotic pathways. Although the molecular settings of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f31011447cb5a800e3e99b0c9e18fdfa
https://doi.org/10.1158/1535-7163.c.6538290.v1
https://doi.org/10.1158/1535-7163.c.6538290.v1
Autor:
Joan Albanell, Ana Rovira, Federico Rojo, Atanasio Pandiella, Ana Lluch, Ignasi Tusquets, Joaquin Arribas, Pilar Eroles, Juan Madoz-Gúrpide, Paula González-Alonso, Cristina Chamizo, Sandra Zazo, Maria Martínez-García, Aura Muntasell, Marta Salido, Laia Serrano, Montserrat Arumi-Uria, Silvia Menendez, Sara García-Alonso, Oriol Arpí, Sonia Servitja, Cristina Guardia, Gabriel Gil-Gómez, MohammadA Sabbaghi
Effects of T-DM1 on 750 cyclin B1 (CCNB1) mRNA expression in T751 DM1 sensitive and resistant breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507875c041da47b06c113042ab33150a
https://doi.org/10.1158/1078-0432.22463774.v1
https://doi.org/10.1158/1078-0432.22463774.v1
Autor:
Joan Albanell, Ana Rovira, Federico Rojo, Atanasio Pandiella, Ana Lluch, Ignasi Tusquets, Joaquin Arribas, Pilar Eroles, Juan Madoz-Gúrpide, Paula González-Alonso, Cristina Chamizo, Sandra Zazo, Maria Martínez-García, Aura Muntasell, Marta Salido, Laia Serrano, Montserrat Arumi-Uria, Silvia Menendez, Sara García-Alonso, Oriol Arpí, Sonia Servitja, Cristina Guardia, Gabriel Gil-Gómez, MohammadA Sabbaghi
Supplementary Figure legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8100eed542345710b968b848c46b8b81
https://doi.org/10.1158/1078-0432.22463768.v1
https://doi.org/10.1158/1078-0432.22463768.v1
Autor:
Joan Albanell, Ana Rovira, Federico Rojo, Atanasio Pandiella, Ana Lluch, Ignasi Tusquets, Joaquin Arribas, Pilar Eroles, Juan Madoz-Gúrpide, Paula González-Alonso, Cristina Chamizo, Sandra Zazo, Maria Martínez-García, Aura Muntasell, Marta Salido, Laia Serrano, Montserrat Arumi-Uria, Silvia Menendez, Sara García-Alonso, Oriol Arpí, Sonia Servitja, Cristina Guardia, Gabriel Gil-Gómez, MohammadA Sabbaghi
Purpose: Trastuzumab-emtansine (T-DM1) is a standard treatment in advanced HER2-positive breast cancer. However, resistance inevitably occurs. We aimed to identify mechanisms of acquired T-DM1 resistance.Experimental Design: HER2-positive breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6060f18e6822572a897febf82a397971
https://doi.org/10.1158/1078-0432.c.6525512.v1
https://doi.org/10.1158/1078-0432.c.6525512.v1
Autor:
Joan Albanell, Ana Rovira, Federico Rojo, Atanasio Pandiella, Ana Lluch, Ignasi Tusquets, Joaquin Arribas, Pilar Eroles, Juan Madoz-Gúrpide, Paula González-Alonso, Cristina Chamizo, Sandra Zazo, Maria Martínez-García, Aura Muntasell, Marta Salido, Laia Serrano, Montserrat Arumi-Uria, Silvia Menendez, Sara García-Alonso, Oriol Arpí, Sonia Servitja, Cristina Guardia, Gabriel Gil-Gómez, MohammadA Sabbaghi
Representative immunohistochemistry images of control and 765 T-DM1 treated explant obtained from a liver metastasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111a881ad9e8f057e9706c954ed8fcaf
https://doi.org/10.1158/1078-0432.22463771
https://doi.org/10.1158/1078-0432.22463771
Autor:
Ion Cristóbal, Paula González-Alonso, Lina Daoud, Esther Solano, Blanca Torrejón, Rebeca Manso, Juan Madoz-Gúrpide, Federico Rojo, Jesús García-Foncillas
Publikováno v:
Marine Drugs, Vol 13, Iss 6, Pp 3276-3286 (2015)
Protein phosphatase 2A (PP2A) is a tumor suppressor complex that has recently been reported as a novel and highly relevant molecular target in prostate cancer (PCa). However, its potential therapeutic value remains to be fully clarified. We treated P
Externí odkaz:
https://doaj.org/article/fc737634dcf647f3b92be0eba3f1b1f6
Autor:
Trupta Purohit, EunGi Kim, Mariusz Jaremko, Joshua M Ray, Hyo Je Cho, Shihan He, Hongzhi Miao, Felicia Gray, Caroline Nikolaidis, Łukasz Jaremko, Tomasz Cierpicki, Qingjie Zhao, Weijiang Ying, Jolanta Grembecka, Xiaotian Zhang, Monica L. Guzman, Shirish Shukla, Alyssa Winkler, Yao Yiwu, Jingya Wang, Russell J.H. Ryan, Paula González-Alonso, Juliano Ndoj, George Lund, Miranda L. Simes
Publikováno v:
Nature chemical biology
Polycomb repressive complex 1 (PRC1) is an essential chromatin-modifying complex that monoubiquitinates histone H2A and is involved in maintaining the repressed chromatin state. Emerging evidence suggests PRC1 activity in various cancers, rationalizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be29ba28e75787c38128d3654fcd1836
https://doi.org/10.1038/s41589-021-00815-5
https://doi.org/10.1038/s41589-021-00815-5
Autor:
Sergei Zari, Juliano Ndoj, Jolanta Grembecka, Paula González-Alonso, Katarzyna Kempińska, Mykhaylo A. Potopnyk, Tomasz Cierpicki, Hongzhi Miao, Caroline Nikolaidis, Andrew D. Henderson, Huang Huang, Trupta Purohit, David S. Rogawski, Shirish Shukla, Christina A. Howard, Adolfo A. Ferrando, Hyo Je Cho, Joshua Abbott, Anna K. Mapp, Maria Luisa Sulis, Hao Li
Publikováno v:
Nature Chemical Biology. 16:1403-1410
The nuclear receptor-binding SET domain (NSD) family of histone methyltransferases is associated with various malignancies, including aggressive acute leukemia with NUP98-NSD1 translocation. While NSD proteins represent attractive drug targets, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50ddaa9b49c0f149319c06274c09039
https://doi.org/10.1038/s41589-020-0626-6
https://doi.org/10.1038/s41589-020-0626-6