Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Paula G Slater"'
1
Akademický článek
Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons.
Autor: Ines Hahn, Andre Voelzmann, Jill Parkin, Judith B Fülle, Paula G Slater, Laura Anne Lowery, Natalia Sanchez-Soriano, Andreas Prokop
Publikováno v: PLoS Genetics, Vol 17, Iss 7, p e1009647 (2021)
The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation is regulated in cells. Focussing on the essential microtubule bundles in axons of Drosophila and Xenopus neurons, we show t
Externí odkaz: https://doaj.org/article/c5e8e8f422334f6baa0209cb9072db39
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2
Akademický článek
Frizzled-5 receptor is involved in neuronal polarity and morphogenesis of hippocampal neurons.
Autor: Paula G Slater, Valerie T Ramirez, Christian Gonzalez-Billault, Lorena Varela-Nallar, Nibaldo C Inestrosa
Publikováno v: PLoS ONE, Vol 8, Iss 10, p e78892 (2013)
The Wnt signaling pathway plays important roles during different stages of neuronal development, including neuronal polarization and dendritic and axonal outgrowth. However, little is known about the identity of the Frizzled receptors mediating these
Externí odkaz: https://doaj.org/article/95b04c0ca9124a4b97c46ea585bc1eaf
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3
Akademický článek
Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells
Autor: Johany Peñailillo, Miriam Palacios, Constanza Mounieres, Rosana Muñoz, Paula G. Slater, Elena De Domenico, Ilya Patrushev, Mike Gilchrist, Juan Larraín
Publikováno v: npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract Xenopus laevis are able to regenerate the spinal cord during larvae stages through the activation of neural stem progenitor cells (NSPCs). Here we use high-resolution expression profiling to characterize the early transcriptome changes induc
Externí odkaz: https://doaj.org/article/8e9c4b3dffcb4bd898001e36e05bb8fc
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4
Akademický článek
Unraveling Axon Guidance during Axotomy and Regeneration
Autor: Miguel E. Domínguez-Romero, Paula G. Slater
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 15, p 8344 (2021)
During neuronal development and regeneration axons extend a cytoskeletal-rich structure known as the growth cone, which detects and integrates signals to reach its final destination. The guidance cues “signals” bind their receptors, activating si
Externí odkaz: https://doaj.org/article/f0afdb2768ee45fd98540251b2376f0a
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5
Akademický článek
Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor
Autor: Paula G. Slater, Sebastian E. Gutierrez-Maldonado, Katia Gysling, Carlos F. Lagos
Publikováno v: Frontiers in Endocrinology, Vol 9 (2018)
The corticotropin-releasing factor (CRF) system is a key mediator of the stress response and addictive behavior. The CRF system includes four peptides: The CRF system includes four peptides: CRF, urocortins I–III, CRF binding protein (CRF-BP) that
Externí odkaz: https://doaj.org/article/995c517ec61a42a6b0aa074acdf77830
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6
Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells
Autor: Paula G. Slater, Michael J. Gilchrist, Ilya Patrushev, Miriam Palacios, Rosana Muñoz, Elena De Domenico, Johany Peñailillo, Constanza Mounieres, Juan Larraín
Publikováno v: npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-15 (2021)
NPJ Regenerative Medicine
npj regenerative medicine 6(1), 68 (2021). doi:10.1038/s41536-021-00179-3
Xenopus laevis are able to regenerate the spinal cord during larvae stages through the activation of neural stem progenitor cells (NSPCs). Here we use high-resolution expression profiling to characterize the early transcriptome changes induced after
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b19970186789f00662c84a6f8803bf6
https://doaj.org/article/8e9c4b3dffcb4bd898001e36e05bb8fc
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7
Spinal Cord Transection In Xenopus laevis Tadpoles
Autor: Paula G, Slater, Juan, Larraín
Publikováno v: Journal of visualized experiments : JoVE. (178)
Spinal cord injury (SCI) is a permanent affliction, which affects the central nervous system (CNS) motor and sensory nerves, resulting in paralysis beneath the injury site. To date, there is no functional recovery therapy for SCI, and there is a lack
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bfe0313845acd9294e3728162510b4b
https://pubmed.ncbi.nlm.nih.gov/34958088
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8
Mitochondrial function in spinal cord injury and regeneration
Autor: Paula G. Slater, Miguel E. Domínguez-Romero, Maximiliano Villarreal, Verónica Eisner, Juan Larraín
Publikováno v: Cellular and molecular life sciences : CMLS. 79(5)
Many people around the world suffer from some form of paralysis caused by spinal cord injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of the central nervous system (CNS), which in mammals is unable to regener
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284403fa1d5dda11f2a6fa1613be0c51
https://pubmed.ncbi.nlm.nih.gov/35416520
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10
Cornifelin expression during Xenopus laevis metamorphosis and in response to spinal cord injury
Autor: Sol Torruella-Gonzalez, Paula G. Slater, Dasfne Lee-Liu, Juan Larraín
Publikováno v: Gene expression patterns : GEP. 43
In a high-throughput RNA sequencing analysis, comparing the transcriptional response between Xenopus laevis regenerative and non-regenerative stages to spinal cord injury, cornifelin was found among the most highly differentially expressed genes. Cor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39665cc1d9b6c5e04c7ad3a85f9b9020
https://pubmed.ncbi.nlm.nih.gov/35151892
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