Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Paula Fresco"'
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 43, Iss 4, Pp 221-222 (2024)
Externí odkaz:
https://doaj.org/article/c6bf5cdaf8a24c4b8db5c246556e2f7c
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 42, Iss 4, Pp 373-383 (2023)
SARS-CoV-2 infection and its clinical manifestations (COVID-19) quickly evolved to a pandemic and a global public health emergency. The limited effectivity of available treatments aimed at reducing virus replication and the lessons learned from other
Externí odkaz:
https://doaj.org/article/5cb3fa711c6843a2b486aba3c467aaa7
Publikováno v:
Cells, Vol 13, Iss 3, p 262 (2024)
Noradrenaline and adrenaline, and their cognate receptors, are currently accepted to participate in cancer progression. They may also participate in cancer initiation, although their role in this phase is much less explored. The aim of this work was
Externí odkaz:
https://doaj.org/article/685012a4186046fdab25ef08ddef4f56
Autor:
Hugo Sevivas, Paula Fresco
Publikováno v:
European Journal of Medical Research, Vol 27, Iss 1, Pp 1-16 (2022)
Abstract Background Resistant chronic migraine is a highly disabling condition which is very difficult to treat. The majority of the treatments for migraine prophylaxis are nonspecific and present weak safety profiles, leading to low adherence and di
Externí odkaz:
https://doaj.org/article/6caac81c93394c7d8e308b481131c533
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 767 (2023)
Physiologically, β-adrenoceptors are major regulators of lipid metabolism, which may be reflected in alterations in lipid droplet dynamics. β-adrenoceptors have also been shown to participate in breast cancer carcinogenesis. Since lipid droplets ma
Externí odkaz:
https://doaj.org/article/b6a54fca3e6a48a7a181f7b0074e0255
Publikováno v:
Revista Portuguesa de Farmacoterapia, Vol 11, Iss 4 (2020)
Drug repurposing (DR, na sigla em inglês; reposicionamento de fármacos, em português) é uma das expressões que tem sido usada para traduzir o processo de descoberta de novos usos terapêuticos para fármacos já aprovados para outras indicaçõe
Externí odkaz:
https://doaj.org/article/2c6cd125f9904a45bb441f7e2f4d6927
Autor:
Filipa Amaro, Dany Silva, Henrique Reguengo, José C. Oliveira, Clara Quintas, Nuno Vale, Jorge Gonçalves, Paula Fresco
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 7968 (2020)
Adrenaline, which participates in the neuroendocrine response that occurs during stress and perimenopause, may be tumorigenic. This exploratory study aimed at investigating whether non-tumorigenic and tumorigenic human breast epithelial cell lines ar
Externí odkaz:
https://doaj.org/article/ae5b7a3f752a44a3bf8c3e30d031edfd
Autor:
Diana Duarte, Filipa Amaro, Isabel Silva, Dany Silva, Paula Fresco, José C. Oliveira, Henrique Reguengo, Jorge Gonçalves, Nuno Vale
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 409 (2019)
Carbidopa is used for the treatment of Parkinson’s disease (PD) as an inhibitor of DOPA decarboxylase, and PD patients taking carbidopa have a lower incidence of various tumors, except for breast cancer and melanoma. Recently, it was shown that car
Externí odkaz:
https://doaj.org/article/8e13e78257f04e9983414324b02bae00
Autor:
Carolina Rocha-Pereira, Silvia Magdalena Arribas, Paula Fresco, Maria Carmen González, Jorge Gonçalves, Carmen Diniz
Publikováno v:
Journal of Pharmacological Sciences, Vol 122, Iss 2, Pp 59-70 (2013)
In hypertension, vascular reactivity alterations have been attributed to numerous factors, including higher sympathetic innervation/adenosine. This study examined the modulation of adenosine receptors on vascular sympathetic nerves and their putative
Externí odkaz:
https://doaj.org/article/eab8dfbee5d544e795c00bdba9fe96ff
Publikováno v:
Molecules, Vol 23, Iss 9, p 2318 (2018)
Although drugs currently used for the various types of diseases (e.g., antiparasitic, antiviral, antibacterial, etc.) are effective, they present several undesirable pharmacological and pharmaceutical properties. Most of the drugs have low bioavailab
Externí odkaz:
https://doaj.org/article/b9704a7209804c3fa234fad622c14e23