Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Paula Fernández-Calotti"'
Autor:
María Pilar Lostao, Carlos Sancho-Mateo, Marçal Pastor-Anglada, Dolors Colomer, Anna Grandas, Paula Fernández-Calotti, Ana Claudio-Montero, Itziar Pinilla-Macua
Publikováno v:
Molecular Pharmaceutics. 12:2158-2166
The abundance and function of transporter proteins at the plasma membrane are likely to be crucial in drug responsiveness. Functional detection of human concentrative nucleoside transporters (hCNTs) is of interest for predicting drug sensitivity beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f694ef65c319cac19a0dfc0bfb7a9b10
https://doi.org/10.1021/acs.molpharmaceut.5b00142
https://doi.org/10.1021/acs.molpharmaceut.5b00142
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 30:1324-1340
Nucleoside analogs are currently used in the treatment of various hematologic malignancies due to their ability to induce apoptosis of lymphoid cells. For nucleoside-derived drugs to exert their action, they must enter cells via nucleoside transporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b042a960300d1cf109ed5ca606439070
https://doi.org/10.1080/15257770.2011.597372
https://doi.org/10.1080/15257770.2011.597372
Autor:
Albert Català, Susana Rives, Nerea Vega-García, Mireia Camós, Liska Caviedes-Cárdenas, Paula Fernández-Calotti, Roberta Malatesta, Marçal Pastor-Anglada
Publikováno v:
Oncotarget
// Albert Catala 1, 2, 6 , Marcal Pastor-Anglada 3, 4, 6 , Liska Caviedes-Cardenas 3 , Roberta Malatesta 5 , Susana Rives 1, 2, 6 , Nerea Vega-Garcia 5 , Mireia Camos 2, 5, 6, * , Paula Fernandez-Calotti 3, 4, 6, * 1 Pediatric Hematology and Oncology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b085f162c6f2ecf8115a2f7ca4c3a137
https://pubmed.ncbi.nlm.nih.gov/27391351
https://pubmed.ncbi.nlm.nih.gov/27391351
Autor:
Francisco Guarner, Paula Fernández-Calotti, María Antolín, Marçal Pastor-Anglada, Olga Casulleras
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30(2)
The intracellular N-terminal domain of the nucleoside and drug transporter human concentrative nucleoside transporter (hCNT)3 was used as bait in a glutathione S-transferase pull-down approach, to identify hCNT3 protein partners, using human colon ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a555efdf9739ba7044e0b371ed13b942
https://pubmed.ncbi.nlm.nih.gov/26481311
https://pubmed.ncbi.nlm.nih.gov/26481311
Autor:
Jorge Geffner, Paula Fernández-Calotti, Romina Gamberale, Mirta Giordano, Julio Cesar Sanchez Avalos, Monica Alejandra Costas
Publikováno v:
International Immunopharmacology. 6:715-723
Fludarabine is a nucleoside analogue that has been successfully employed for the treatment of low-grade lymphoid malignancies and, more recently, in nonmyeloablative preparative regimens for stem cell transplantation, due to its strong cytotoxic acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b8e9d067e047dd71feb3636e964f36
https://doi.org/10.1016/j.intimp.2005.08.027
https://doi.org/10.1016/j.intimp.2005.08.027
Autor:
Carlos M. Galmarini, Paula Fernández-Calotti, Mirta Giordano, Charles Dumontet, Lars Petter Jordheim
Publikováno v:
Leukemia & Lymphoma. 46:335-346
Acute myelogenous leukemia (AML) is the most common form of acute leukemia in adults. After diagnosis, patients with AML are mainly treated with standard induction chemotherapy combining cytarabine (araC) and anthracyclines. The majority of them achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea3ceba6843b1a0b8026888c949053c
https://doi.org/10.1080/10428190400015683
https://doi.org/10.1080/10428190400015683
Autor:
Mónica Vermeulen, Diego Martínez, Silvina Raiden, Mirta Giordano, Romina Gamberale, Analía Silvina Trevani, Jorge Geffner, Gabriela Salamone, Paula Fernández-Calotti
Publikováno v:
Immunology. 113:355-362
We have previously reported that human neutrophils pretreated with tumour necrosis factor-alpha (TNF-alpha) and then exposed to a variety of agents such as immune complexes, zymosan, phorbol 12-myristate 13-acetate (PMA), C5a, fMLP, or granulocyte-ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e94fb0b3d8df90399255fade972668
https://doi.org/10.1111/j.1365-2567.2004.01973.x
https://doi.org/10.1111/j.1365-2567.2004.01973.x
Autor:
Paula Fernández-Calotti, Julieta Sanjurjo, Romina Gamberale, Silvina Raiden, Analía Silvina Trevani, Jorge Geffner, Mirta Giordano, Christine Sedlik, Mónica Vermeulen, Gabriela Salamone
Publikováno v:
The Journal of Immunology. 172:3196-3204
It is widely appreciated that inflammatory responses in peripheral tissues are usually associated to the development of acidic microenvironments. Despite this, there are few studies aimed to analyze the effect of extracellular pH on immune cell funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00da449f3779997a61091b27dc33768e
https://doi.org/10.4049/jimmunol.172.5.3196
https://doi.org/10.4049/jimmunol.172.5.3196
Autor:
Carlos M. Galmarini, Paula Fernández-Calotti, Jorge Geffner, Julio César Sánchez-Ávalos, Mirta Giordano, Lars Petter Jordheim, Charles Dumontet, Romina Gamberale
Publikováno v:
Biochemical Pharmacology. 66:2185-2191
Administration of the adenosine analogue fludarabine (FLU) in vivo induces a profound and prolonged T lymphopenia which mainly affects CD4+ cells. To better understand the mechanistic basis underlying this preferential depletion, we analyzed the in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304ee812d97998ba17edc032127b06a9
https://doi.org/10.1016/j.bcp.2003.07.008
https://doi.org/10.1016/j.bcp.2003.07.008
Publikováno v:
Molecular pharmaceutics. 11(9)
Ribavirin is a broad spectrum antiviral that increases the response rate in chronic hepatitis C patients when administered in combination with IFNα. Ribavirin is a purine nucleoside derivative, transported into hepatocytes by nucleoside transporters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b97a80aaa72238bc357587fb7b0554d
https://pubmed.ncbi.nlm.nih.gov/24957263
https://pubmed.ncbi.nlm.nih.gov/24957263