Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Paula Embury"'
Autor:
Emily R. Hannon, Carmen J. Marsit, Arlene E. Dent, Paula Embury, Sidney Ogolla, David Midem, Scott M. Williams, James W. Kazura
Publikováno v:
BioData Mining, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract Background Changing cell-type proportions can confound studies of differential gene expression or DNA methylation (DNAm) from peripheral blood mononuclear cells (PBMCs). We examined how cell-type proportions derived from the transcriptome ve
Externí odkaz:
https://doaj.org/article/8597c2e5e77243ba82997ddda9ac652c
Autor:
Katherine R. Dobbs, Paula Embury, Emmily Koech, Sidney Ogolla, Stephen Munga, James W. Kazura, Arlene E. Dent
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Background Age-related changes in adaptive and innate immune cells have been associated with a decline in effective immunity and chronic, low-grade inflammation. Epigenetic, transcriptional, and functional changes in monocytes occur with agi
Externí odkaz:
https://doaj.org/article/b5de2685d0b942f9b7fcbb23589b6e2c
Autor:
Brook Jeang, Ming-Chieh Lee, Paula Embury, Delenasaw Yewhalaw, David Narum, Christopher King, Wai-Hong Tham, James Kazura, Guiyun Yan, Arlene Dent
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 108:871-881
As malaria control and elimination efforts ramp up in Ethiopia, more sensitive tools for assessing exposure to coendemic Plasmodium falciparum and Plasmodium vivax are needed to accurately characterize malaria risk and epidemiology. Serological marke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc22298d767fbddea68c3f987cefc4bd
https://doi.org/10.4269/ajtmh.22-0645
https://doi.org/10.4269/ajtmh.22-0645
Autor:
Katherine R, Dobbs, Arlene E, Dent, Paula, Embury, Sidney, Ogolla, Emmily, Koech, David, Midem, James W, Kazura
Publikováno v:
International Journal for Parasitology. 52:717-720
Children under the age of 5 years living in areas of moderate to high malaria transmission are highly susceptible to clinical malaria with fever that prompts treatment of blood stage infection with anti-malarial drugs. In contrast, older school age c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81a8bba8b0ccd1b39391f5183276b0e
https://doi.org/10.1016/j.ijpara.2022.07.001
https://doi.org/10.1016/j.ijpara.2022.07.001
Autor:
Arlene E. Dent, Emmily Koech, James W. Kazura, Stephen Munga, Paula Embury, Sidney Ogolla, Katherine R. Dobbs
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-14 (2021)
Immunity & Ageing : I & A
Immunity & Ageing : I & A
Background Age-related changes in adaptive and innate immune cells have been associated with a decline in effective immunity and chronic, low-grade inflammation. Epigenetic, transcriptional, and functional changes in monocytes occur with aging, thoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9911dbf9e35b7ac7de9d35deba68aa01
https://doi.org/10.21203/rs.3.rs-80601/v1
https://doi.org/10.21203/rs.3.rs-80601/v1
Autor:
Peter Mungai, Paula Embury, Arlene E. Dent, Indu Malhotra, Christopher L. King, Timothy S. Anderson, Kee Thai Yeo, James W. Kazura
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(5)
Infections during pregnancy can expose the fetus to microbial Ags, leading to inflammation that affects B cell development. Prenatal fetal immune priming may have an important role in infant acquisition of pathogen-specific immunity. We examined plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172c953c5747413c9db081be4f6b1dd9
https://pubmed.ncbi.nlm.nih.gov/30674575
https://pubmed.ncbi.nlm.nih.gov/30674575
Autor:
Bruce A. Rosa, Arlene E. Dent, Katherine R. Dobbs, Makedonka Mitreva, John M. Vulule, James W. Kazura, Peter Sumba Odada, Paula Embury
Background Inflammation and monocytes are thought to be important to human malaria pathogenesis. However, the relationship of inflammation and various monocyte functions to acute malaria, recovery from acute malaria, and asymptomatic parasitemia in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10e42c46ac18171117955501795b1cc
https://europepmc.org/articles/PMC5621919/
https://europepmc.org/articles/PMC5621919/
Autor:
Chandy C. John, Daniel J. Tisch, James W. Kazura, Ann M. Moormann, Charles H. King, Peter Odada Sumba, Paula Embury
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 81:489-495
Long-term planning to prevent malaria epidemics requires in-depth understanding of immunity to Plasmodium falciparum in areas of unstable transmission. Cytokine responses to immunodominant epitope peptides from liver stage antigen 1 (LSA-1) and throm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12b9e889b2bed9e9a27a1c17d225f71
https://doi.org/10.4269/ajtmh.2009.81.489
https://doi.org/10.4269/ajtmh.2009.81.489
Autor:
Chandy C. John, Peter Odada Sumba, Paula Embury, James W. Kazura, Ann M. Moormann, Daniel J. Tisch
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 74:585-590
The stability of anti-malarial immunity will influence the interpretation of immunologic endpoints during malaria vaccine trials conducted in endemic areas. Therefore, we evaluated cytokine responses to Plasmodium falci- parum liver stage antigen-1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb9e89f338726a3ae935343c7a05e91
https://doi.org/10.4269/ajtmh.2006.74.585
https://doi.org/10.4269/ajtmh.2006.74.585
Autor:
Ayub V. Ofulla, Chandy C. John, Paula Embury, Peter Odada Sumba, Ann M. Moormann, James W. Kazura
Publikováno v:
Annals of Tropical Medicine & Parasitology. 99:431-435
(2005). Age-related differences in the detection of Plasmodium falciparum infection by PCR and microscopy, in an area of Kenya with holo-endemic malaria. Annals of Tropical Medicine & Parasitology: Vol. 99, No. 4, pp. 431-435.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d153c8fe98043c4e96a13c16926f631
https://doi.org/10.1179/136485905x36316
https://doi.org/10.1179/136485905x36316