Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paula Dilger"'
Publikováno v:
Journal of Immunological Methods. 397:1-7
Two candidate preparations of human sequence recombinant Interleukin-2 (IL-2) were formulated and lyophilized at NIBSC prior to evaluation in a collaborative study for their suitability to serve as a replacement international standard. The preparatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012f62229b5fde0d25cfcdc501847e6d
https://doi.org/10.1016/j.jim.2013.07.012
https://doi.org/10.1016/j.jim.2013.07.012
Autor:
Meenu Wadhwa, David Eastwood, Susan J. Thorpe, Chris Bird, Paula Dilger, Lucy Findlay, Stephen Poole, Richard Stebbings, Robin Thorpe, Jason Hockley
Publikováno v:
British Journal of Clinical Pharmacology
Aim To determine if cytokine release with a solid phase assay is predictive of adverse responses for a range of therapeutic mAbs. Methods Cytokine ELISAs and a multi-array system were used to compare responses generated by different therapeutic mAbs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929329117f2a06d2fcb093c474b38bf8
https://doi.org/10.1111/bcp.12165
https://doi.org/10.1111/bcp.12165
Autor:
Guoping Wu, Gao Kai, David Bending, Anne Cooke, John A Little, Chris Bird, Robin Thorpe, David Bender, Weihong Wang, Michelle Hamill, Paula Dilger, Tony Wyss-Coray, Katherine M. Getliffe, Alan B Heath, Meenu Wadhwa, Jo Read, Hui Zhang, Sarah Gibbs
Publikováno v:
Journal of Immunological Methods. 380:1-9
One candidate preparation of human sequence recombinant transforming growth factor-β3 (TGF-β3) was formulated and lyophilized at NIBSC prior to evaluation in a collaborative study for its suitability to serve as an international standard. The prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aed52c1490f76c19499b5d54b77eca3
https://doi.org/10.1016/j.jim.2012.03.002
https://doi.org/10.1016/j.jim.2012.03.002
Autor:
M. Jerhard Seghatchian, Pranee Krailadisiri, Meenu Wadhwa, Robin Thorpe, Dawn Sands, Marcela Contreras, Paula Dilger
Publikováno v:
Transfusion. 40:1118-1126
BACKGROUND Several studies have suggested that cytokine accumulation during storage of platelet concentrates (PCs) may mediate nonhemolytic febrile transfusion reactions and that a reduction in WBC numbers prevents the generation of cytokines. Despit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b84b672eaf099f8110ddf1ebb66fa0
https://doi.org/10.1046/j.1537-2995.2000.40091118.x
https://doi.org/10.1046/j.1537-2995.2000.40091118.x
Autor:
James G. Files, Daniel Kramer, Chris Bird, Susan Goelz, Jaya Goyal, Michael G. Tovey, Meena Subramanyam, Paula Dilger, Christophe Lallemand, Wendy Jones, Meenu Wadhwa, Vijay Jethwa, Robin Thorpe
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 33(11)
Effective monitoring of the development of neutralizing antibodies (NAbs) against IFN-β in multiple sclerosis (MS) patients on IFN-β therapy is important for clinical decision making and disease management. To date, antiviral assays have been the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1296cc2e44c256b1a2e3724cfe7df4
https://pubmed.ncbi.nlm.nih.gov/23848523
https://pubmed.ncbi.nlm.nih.gov/23848523
Autor:
Zaed Z R, Hamady, Nigel, Scott, Mark D, Farrar, Meenu, Wadhwa, Paula, Dilger, Terence R, Whitehead, Robin, Thorpe, Keith T, Holland, J Peter A, Lodge, Simon R, Carding
Publikováno v:
Inflammatory bowel diseases. 17(9)
While cytokine therapy and the use of immunosuppressive cytokines such as transforming growth factor-β (TGF-β) offer great potential for the treatment of inflammatory bowel disease (IBD), issues concerning formulation, stability in vivo, delivery t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5e9d3db215f655c4a5426a592b925ec
https://pubmed.ncbi.nlm.nih.gov/21830271
https://pubmed.ncbi.nlm.nih.gov/21830271
Publikováno v:
AIDS. 5:321-324
Antisera from sheep immunized with two different recombinant soluble CD4 preparations both exhibited cross-reactive antibodies specific for recombinant gp120s and gp160s prepared in different expression systems in immunoblots and radiobinding assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab33027bece4ba6a29e85df4838f883
https://doi.org/10.1097/00002030-199103000-00013
https://doi.org/10.1097/00002030-199103000-00013
Autor:
Bernard P. Mahon, Meenu Wadhwa, Trevor W. Barrowcliffe, Paula Dilger, Jill E Tubbs, Robin Thorpe
Publikováno v:
British journal of haematology. 82(3)
We have continued our previous study of the inhibitory effects of factor VIII concentrates on IL-2 secretion by T cells. Experiments with an extended range of products confirm our previous conclusion that some but not all low, intermediate and high p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253d7b4c436a128dc10893330da59a0a
https://pubmed.ncbi.nlm.nih.gov/1486038
https://pubmed.ncbi.nlm.nih.gov/1486038
Autor:
Robin Thorpe, Christopher R. Ling, Mark Page, Alan B Heath, Cherelyn Vella, Terry Corcoran, Paula Dilger
Publikováno v:
AIDS (London, England). 6(5)
Objective To identify epitopes on HIV-1 gp120 that correlate with disease resistance and/or prognostic indication. Design The identification of epitopes on HIV-1 gp120 was determined by testing the reactivity by immunoblotting of anti-HIV-positive hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20c38c04cbe3e6f2b7c90e4eb54c920
https://pubmed.ncbi.nlm.nih.gov/1616648
https://pubmed.ncbi.nlm.nih.gov/1616648
Publikováno v:
Biochemical pharmacology. 30(20)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af50acbbe1aa502634d7df5127a8d075
https://pubmed.ncbi.nlm.nih.gov/7317083
https://pubmed.ncbi.nlm.nih.gov/7317083