The Gastrointestinal Load of Carbapenem-Resistant Enterobacteriacea Is Associated With the Transition From Colonization to Infection by Klebsiella pneumoniae Isolates Harboring the blaKPC Gene

Autor: Letícia Busato Migliorini, Laura Leaden, Romário Oliveira de Sales, Nathalia Pellegrini Correa, Maryana Mara Marins, Paula Célia Mariko Koga, Alexandra do Rosario Toniolo, Fernando Gatti de Menezes, Marines Dalla Valle Martino, Jesús Mingorance, Patricia Severino

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

BackgroundHealthcare-associated infections by carbapenem-resistant Klebsiella pneumoniae are difficult to control. Virulence and antibiotic resistance genes contribute to infection, but the mechanisms associated with the transition from colonization

Externí odkaz: https://doaj.org/article/c02b85259645489196c4188af8218bee

Desafio no diagnóstico de estrongiloidíase pulmonar

Autor: Andrea dos Santos Pereira, Alexandre Gimenes Marques, André Mario Doi, Marinês Dalla Valle Martino, Paula Célia Mariko Koga, Vivian Renata Chiarato, Liang Fung, Rima Batah Martins, Jacyr Pasternak

Publikováno v: Einstein (São Paulo), Vol 17, Iss 1

Externí odkaz: https://doaj.org/article/bf3ba23b818f44beb63fb604d53259e4

Prevalence of blakpc‐2, blakpc‐3 and blakpc‐30—carrying plasmids in Klebsiella pneumoniae isolated in a brazilian hospital

Autor: Romário Oliveira de Sales, Ana Cristina Gales, AR Toniolo, Marines Dalla Valle Martino, Andre Mario Doi, Paula Célia Mariko Koga, Letícia Busato Migliorini, Patrícia Severino, Fernando Menezes, Holger Brüggemann, Anja Poehlein

Publikováno v: Migliorini, L B, de Sales, R O, Koga, P C M, Doi, A M, Poehlein, A, Toniolo, A R, Menezes, F G, Martino, M D V, Gales, A C, Brüggemann, H & Severino, P 2021, ' Prevalence of blakpc-2, blakpc-3 and blakpc-30—carrying plasmids in Klebsiella pneumoniae isolated in a brazilian hospital ', Pathogens, vol. 10, no. 3, 332 . https://doi.org/10.3390/pathogens10030332
Pathogens, Vol 10, Iss 332, p 332 (2021)
Pathogens
Volume 10
Issue 3

Klebsiella pneumoniae carbapenemase (KPC) actively hydrolyzes carbapenems, antibiotics often used a last-line treatment for multidrug-resistant bacteria. KPC clinical relevance resides in its widespread dissemination. In this work, we report the geno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75fcf08ee781d2109c2487444a11511
https://pure.au.dk/portal/da/publications/prevalence-of-blakpc2-blakpc3-and-blakpc30carrying-plasmids-in-klebsiella-pneumoniae-isolated-in-a-brazilian-hospital(a9e2593a-31ca-4b30-913d-0c4e4d7b154e).html

Comparative Genomics of Nonoutbreak Pseudomonas aeruginosa Strains Underlines Genome Plasticity and Geographic Relatedness of the Global Clone ST235

Autor: Anders Jensen, Anja Poehlein, Holger Brüggemann, Paula Célia Mariko Koga, Romario Oliveira de Sales, Andre Mario Doi, Patrícia Severino, Letícia Busato Migliorini, Elzbieta Brzuszkiewicz, Andrea Vieira de Souza, Jacyr Pasternak, Marines Dalla Valle Martino

Publikováno v: Genome Biology and Evolution
Brüggemann, H, Migliorini, L B, Oliveira de Sales, R, Mariko Koga, P C, de Souza, A V, Jensen, A, Poehlein, A, Brzuszkiewicz, E, Doi, A M, Pasternak, J, Martino, M D V & Severino, P 2018, ' Comparative genomics of non-outbreak Pseudomonas aeruginosa strains underlines genome plasticity and geographic relatedness of the global clone ST235 ', Genome Biology and Evolution, vol. 10, no. 7, pp. 1852-1857 . https://doi.org/10.1093/gbe/evy139

Pseudomonas aeruginosa is an important opportunistic pathogen in hospitals, responsible for various infections that are difficult to treat due to intrinsic and acquired antibiotic resistance. Here, twenty epidemiologically unrelated strains isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2581313d265593839083a440a2ae45
http://europepmc.org/articles/PMC6063271

Mutagenesis Induced by Sub-Lethal Doses of Ciprofloxacin: Genotypic and Phenotypic Differences Between the Pseudomonas aeruginosa Strain PA14 and Clinical Isolates

Autor: Andrea Vieira de Souza, Patrícia Severino, Romario Oliveira de Sales, Marines Dalla Valle Martino, Holger Brüggemann, Rodrigo S. Galhardo, Letícia Busato Migliorini, Paula Célia Mariko Koga

Publikováno v: Frontiers in Microbiology, Vol 10 (2019)
Migliorini, L B, Brüggemann, H, de Sales, R O, Koga, P C M, de Souza, A V, Martino, M D V, Galhardo, R S & Severino, P 2019, ' Mutagenesis Induced by Sub-Lethal Doses of Ciprofloxacin : Genotypic and Phenotypic Differences Between the Pseudomonas aeruginosa Strain PA14 and Clinical Isolates ', Frontiers in Microbiology, vol. 10, 1553 . https://doi.org/10.3389/fmicb.2019.01553
Frontiers in Microbiology

Bacterial resistance is a severe threat to global public health. Exposure to sub-lethal concentrations has been considered a major driver of mutagenesis leading to antibiotic resistance in clinical settings. Ciprofloxacin is broadly used to treat inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccc2e9d5e417a1c2f54b34650c6e0bb
https://www.frontiersin.org/article/10.3389/fmicb.2019.01553/full