Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paula Burger"'
Autor:
E. Niclas Jonsson, Christian Hove Rasmussen, Paula Burger, Mike K. Smith, Luke Fostvedt, Lynn McFadyen, Vijayakumar Sundararajan, Mats O. Magnusson, Timothy Nicholas, Thomas G. Tensfeldt, Kaori Ito
Publikováno v:
The AAPS journal. 20(3)
Every year, the pharmaceutical industry generates a large number of scientific reports related to drug research, development, and regulatory submissions. Many of these reports are created using text processing tools such as Microsoft Word. Given the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe726174d29dc4d74e4b6284340a1e7
https://pubmed.ncbi.nlm.nih.gov/29549459
https://pubmed.ncbi.nlm.nih.gov/29549459
Publikováno v:
Epilepsia. 52(2)
By reducing neuronal excitability through selective binding to the α(2)δ subunit of voltage-dependent calcium channels, pregabalin effectively treats epilepsy, chronic pain, and anxiety disorders. To evaluate if pregabalin coadministration affects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2061c375ac47136dd37d4a0b9d4bc344
https://pubmed.ncbi.nlm.nih.gov/21314678
https://pubmed.ncbi.nlm.nih.gov/21314678
Publikováno v:
Epilepsia. 52(2)
Pregabalin, a high-affinity ligand for α2δ subunits of voltage-gated calcium channels, is a novel pharmacotherapy for chronic pain, partial seizures, and other disorders. The present study investigated the population pharmacokinetics of pregabalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ab3a8dbef478a481c1604898adcfdb2
https://pubmed.ncbi.nlm.nih.gov/21269291
https://pubmed.ncbi.nlm.nih.gov/21269291
Publikováno v:
Epilepsia.
By reducing neuronal excitability through selective binding to the α(2)δ subunit of voltage-dependent calcium channels, pregabalin effectively treats epilepsy, chronic pain, and anxiety disorders. To evaluate if pregabalin coadministration affects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8fbeb08d84eda22f15b08e393cc8d85
https://doi.org/10.1111/j.1528-1167.2010.02763.x
https://doi.org/10.1111/j.1528-1167.2010.02763.x
Autor:
Howard Norman Bockbrader, S. Chapel, Paula Burger, Raymond Miller, Nancy Janiczek, David L. Wesche
Publikováno v:
Clinical pharmacokinetics. 49(10)
Pregabalin and gabapentin share a similar mechanism of action, inhibiting calcium influx and subsequent release of excitatory neurotransmitters; however, the compounds differ in their pharmacokinetic and pharmacodynamic characteristics. Gabapentin is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a11d3cc7e5ee62cb1e13a99465b4ba5
https://pubmed.ncbi.nlm.nih.gov/20818832
https://pubmed.ncbi.nlm.nih.gov/20818832
Autor:
B. Zeiher, Lynne Pauer, Marci L. Chew, Kaori Ito, Wonkyung Byon, Daniele Ouellet, Brian Corrigan, Paula Burger
Publikováno v:
Journal of clinical pharmacology. 50(7)
Data from 4 phase 2/3 studies were pooled to characterize the exposure response of daily pregabalin (150-600 mg) in patients with fibromyalgia using self-assessed daily pain scores (PAIN) and end-of-treatment patient global impression of change (PGIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c027b9f12630f3dc333cd14dd575ab
https://pubmed.ncbi.nlm.nih.gov/20357295
https://pubmed.ncbi.nlm.nih.gov/20357295
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 34(6)
Objective: To characterize change from baseline weight over time for pregabalin and placebo administration. Methods: Asymptotic fraction of baseline weight was modeled with a nonmixture model and a mixture model as a function of baseline weight, expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd976f17c288cf2e0ef772ad4e94071
https://pubmed.ncbi.nlm.nih.gov/17690866
https://pubmed.ncbi.nlm.nih.gov/17690866
Autor:
Raymond Miller, Howard Norman Bockbrader, E. A. Garofalo, Richard L. Lalonde, Bill Frame, Paula Burger, Brian Corrigan
Publikováno v:
Clinical pharmacology and therapeutics. 73(6)
Objective Our objectives were to describe the exposure-response relationship of pregabalin add-on treatment for refractory partial seizures after multiple dosing in patients and to identify the factors that influence this relationship. Methods A mixe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0aad19d040f8f251e6233b6cb7ac6f
https://pubmed.ncbi.nlm.nih.gov/12811359
https://pubmed.ncbi.nlm.nih.gov/12811359
Publikováno v:
Clinical Pharmacology & Therapeutics. 79:P44-P44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4e3901417d880489748084fd0915534
https://doi.org/10.1016/j.clpt.2005.12.154
https://doi.org/10.1016/j.clpt.2005.12.154
Publikováno v:
Journal of Pharmacokinetics & Pharmacodynamics; Dec2007, Vol. 34 Issue 6, p753-770, 18p