Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Paula Abou Karam"'
Autor:
Carmen Fernandez‐Becerra, Patrícia Xander, Daniel Alfandari, George Dong, Iris Aparici‐Herraiz, Irit Rosenhek‐Goldian, Mehrdad Shokouhy, Melisa Gualdron‐Lopez, Nicholy Lozano, Nuria Cortes‐Serra, Paula Abou Karam, Paula Meneghetti, Rafael Pedro Madeira, Ziv Porat, Rodrigo Pedro Soares, Adriana Oliveira Costa, Sima Rafati, Anabela‐Cordeiro da Silva, Nuno Santarém, Christopher Fernandez‐Prada, Marcel I. Ramirez, Dolores Bernal, Antonio Marcilla, Vera Lucia Pereira‐Chioccola, Lysangela Ronalte Alves, Hernando Del Portillo, Neta Regev‐Rudzki, Igor Correia deAlmeida, Sergio Schenkman, Martin Olivier, Ana Claudia Torrecilhas
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 10, Pp n/a-n/a (2023)
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular v
Externí odkaz:
https://doaj.org/article/abb07027d5734768a2837438788e98db
Autor:
Alon Nudelman, Anjana Shenoy, Hyla Allouche-Arnon, Michal Fisler, Irit Rosenhek-Goldian, Lior Dayan, Paula Abou Karam, Ziv Porat, Inna Solomonov, Neta Regev-Rudzki, Amnon Bar-Shir, Irit Sagi
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 434 (2024)
Proteolysis of the extracellular matrix (ECM) by matrix metalloproteinases (MMPs) plays a crucial role in the immune response to bacterial infections. Here we report the secretion of MMPs associated with proteolytic extracellular vesicles (EVs) relea
Externí odkaz:
https://doaj.org/article/b0a5d6ff48364c648a48f59bc6e7c9ef
Autor:
Yifat Ofir-Birin, Hila Ben Ami Pilo, Abel Cruz Camacho, Ariel Rudik, Anna Rivkin, Or-Yam Revach, Netta Nir, Tal Block Tamin, Paula Abou Karam, Edo Kiper, Yoav Peleg, Reinat Nevo, Aryeh Solomon, Tal Havkin-Solomon, Alicia Rojas, Ron Rotkopf, Ziv Porat, Dror Avni, Eli Schwartz, Thomas Zillinger, Gunther Hartmann, Antonella Di Pizio, Neils Ben Quashie, Rivka Dikstein, Motti Gerlic, Ana Claudia Torrecilhas, Carmit Levy, Esther N. M. Nolte-‘t Hoen, Andrew G. Bowie, Neta Regev-Rudzki
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The chemokine CXCL10 is associated with pathogenesis of cerebral malaria in Plasmodium falciparum infection. Here the authors show that P. falciparum produces extracellular vesicles laden with RNAs that are taken up by monocytes resulting in a RIG-I
Externí odkaz:
https://doaj.org/article/224e6a94586f481d8f075fa74b8e8bf3
Autor:
Elya Dekel, Dana Yaffe, Irit Rosenhek-Goldian, Gili Ben-Nissan, Yifat Ofir-Birin, Mattia I. Morandi, Tamar Ziv, Xavier Sisquella, Matthew A. Pimentel, Thomas Nebl, Eugene Kapp, Yael Ohana Daniel, Paula Abou Karam, Daniel Alfandari, Ron Rotkopf, Shimrit Malihi, Tal Block Temin, Debakshi Mullick, Or-Yam Revach, Ariel Rudik, Nir S. Gov, Ido Azuri, Ziv Porat, Giulia Bergamaschi, Raya Sorkin, Gijs J. L. Wuite, Ori Avinoam, Teresa G. Carvalho, Sidney R. Cohen, Michal Sharon, Neta Regev-Rudzki
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Plasmodium falciparum secretes extracellular vesicles (EVs) while growing inside red blood cells (RBCs). Here the authors show that these EVs contain assembled and functional 20S proteasome complexes that remodel the cytoskeleton of naïve human RBCs
Externí odkaz:
https://doaj.org/article/2714bdc7c6d440079ba403f2120173c1
Autor:
Daniel Alfandari, Hila Ben Ami Pilo, Paula Abou Karam, Osnat Dagan, Carine Joubran, Ron Rotkopf, Neta Regev-Rudzki, Ziv Porat
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Extracellular vesicles (EVs) are produced by across almost all the living kingdoms and play a crucial role in cell-cell communication processes. EVs are especially important for pathogens, as Plasmodium falciparum (Pf) parasite, the leading causing s
Externí odkaz:
https://doaj.org/article/31123daf3de841f4b3b7bee5455c0d47
Autor:
Xavier Sisquella, Yifat Ofir-Birin, Matthew A. Pimentel, Lesley Cheng, Paula Abou Karam, Natália G. Sampaio, Jocelyn Sietsma Penington, Dympna Connolly, Tal Giladi, Benjamin J. Scicluna, Robyn A. Sharples, Andreea Waltmann, Dror Avni, Eli Schwartz, Louis Schofield, Ziv Porat, Diana S. Hansen, Anthony T. Papenfuss, Emily M. Eriksson, Motti Gerlic, Andrew F. Hill, Andrew G. Bowie, Neta Regev-Rudzki
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
STING is an intracellular DNA sensor that can alter response to infection, but in the case of malaria it is unclear how parasite DNA in red blood cells (RBCs) reaches DNA sensors in immune cells. Here the authors show that STING in human monocytes ca
Externí odkaz:
https://doaj.org/article/144b9d639c34432f83aff80548d8d525
Autor:
Andrea Galisova, Jiri Zahradnik, Hyla Allouche-Arnon, Mattia I. Morandi, Paula Abou Karam, Michal Fisler, Ori Avinoam, Neta Regev-Rudzki, Gideon Schreiber, Amnon Bar-Shir
Publikováno v:
ACS Nano. 16:12276-12289
The elucidation of viral-receptor interactions and an understanding of virus-spreading mechanisms are of great importance, particularly in the era of a pandemic. Indeed, advances in computational chemistry, synthetic biology, and protein engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2d392c6aae7da09884c389f6f03316
https://doi.org/10.1021/acsnano.2c03119
https://doi.org/10.1021/acsnano.2c03119
Publikováno v:
Biomedicines, Vol 8, Iss 5, p 98 (2020)
Extracellular vesicles (EVs) are cell-derived membrane-bound structures that are believed to play a major role in intercellular communication by allowing cells to exchange proteins and genetic cargo between them. In particular, pathogens, such as the
Externí odkaz:
https://doaj.org/article/3a5cfd7f61f04d4bbc4aae04a9d0f351
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Extracellular vesicles are essential for long distance cell–cell communication. They function as carriers of different compounds, including proteins, lipids and nucleic acids. Pathogens, like malaria parasites (Plasmodium falciparum, Pf), excel in
Externí odkaz:
https://doaj.org/article/ec735a8b1d354828b1f486244033082a
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2470
Malaria is one the most devastating infectious diseases in the world: of the five malaria-associated parasites, Plasmodium falciparum and P. vivax are the most pathogenic and widespread, respectively. P. falciparum invades human red blood cells (RBCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6dac66129ee6ccb7bac882584460780
https://pubmed.ncbi.nlm.nih.gov/35881344
https://pubmed.ncbi.nlm.nih.gov/35881344