Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Paula A. Lengerke-Diaz"'
Autor:
Manoj Kumar Kashyap, Hiren Karathia, Deepak Kumar, Roberto Vera Alvarez, Jose Vicente Forero-Forero, Eider Moreno, Juliana Velez Lujan, Carlos Ivan Amaya-Chanaga, Newton Medeiros Vidal, Zhe Yu, Emanuela M. Ghia, Paula A. Lengerke-Diaz, Daniel Achinko, Michael Y. Choi, Laura Z. Rassenti, Leonardo Mariño-Ramírez, Stephen M. Mount, Sridhar Hannenhalli, Thomas J. Kipps, Januario E. Castro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102202- (2024)
Splicing factor 3b subunit 1 (SF3B1) is the largest subunit and core component of the spliceosome. Inhibition of SF3B1 was associated with an increase in broad intron retention (IR) on most transcripts, suggesting that IR can be used as a marker of s
Externí odkaz:
https://doaj.org/article/adf59c81f6f94126a63b606708311ab5
Autor:
Januario E. Castro, Paula A. Lengerke-Diaz, Juliana Velez Lujan, Michael Y. Choi, Eider F. Moreno-Cortes, Jose V. Forero, Juan Esteban Garcia-Robledo, Chaja Jacobs, Colin McCarthy, Alaina Heinen, Carlos I. Amaya-Chanaga, Thomas J. Kipps
Publikováno v:
Advances in Hematology, Vol 2022 (2022)
Ibrutinib-based therapies are costly and require continuous administration. We hypothesized combining BTK inhibition with anti-CD20 monoclonal antibodies would yield deep remissions allowing discontinuation. We enrolled 32 therapy-naïve CLL patients
Externí odkaz:
https://doaj.org/article/4b490b66d62e48f895bce6b2d0f5c71a
Autor:
Juliana Velez Lujan, Paula A. Lengerke-Diaz, Chaja Jacobs, Eider F. Moreno-Cortes, Cesar A. Ramirez-Segura, Michael Y. Choi, Colin McCarthy, Alaina Heinen, Thomas J. Kipps, Januario E. Castro
Publikováno v:
Haematologica, Vol 105, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/3223f9545c044e6aae193db6725df666
Autor:
Manoj Kumar Kashyap, Hiren Karathia, Deepak Kumar, Roberto Vera Alvarez, Paula A Lengerke-Diaz, Jose Vicente Forero-Forero, Eider Moreno, Juliana Velez Lujan, Carlos Ivan Amaya-Chanaga, Newton Medeiros Vidal, Zhe Yu, Daniel Achinko, Emanuela M. Ghia, Michael Y. Choi, Laura Z. Rassenti, Leonardo Mariño-Ramírez, Stephen M. Mount, Sridhar Hannenhalli, Thomas J. Kipps, Januario E. Castro
BackgroundAlternative splicing (AS) is a fundamental process in eukaryotes contributing to the diversity of mRNA isoforms with variable ratios of intron/exon. SF3B1 is a pivotal protein of the spliceosome machinery. Mutations in the SF3B1 gene have p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9780fc833c4337eeaff49ae6153d3bf
https://doi.org/10.21203/rs.3.rs-1622375/v1
https://doi.org/10.21203/rs.3.rs-1622375/v1
Autor:
Juan José Hurtado-Guerra, Juan Sebastián Peinado-Acevedo, Fabián Jaimes, Carolina Hincapié, José Roberto Uribe-Delgado, Paula A. Lengerke-Diaz, Santiago Giraldo-Ramírez, Juanita Mesa-Abad
Publikováno v:
Clinical Infectious Diseases. 73:e1151-e1157
Background Infective endocarditis (IE) secondary to Staphylococcus aureus bacteremia (SAB) has high morbidity and mortality. The systematic use of echocardiography in SAB is controversial. We aimed to validate VIRSTA and Predicting Risk of Endocardit
Autor:
Juliana Velez-Lujan, Jose V. Forero, Paula A. Lengerke-Diaz, Carlos I. Amaya-Chanaga, Alaina Heinen, Juan Esteban Garcia-Robledo, Colin McCarthy, Michale Y. Choi, Eider F. Moreno-Cortes, Chaja Jacobs, Thomas J. Kipps, Januario E. Castro
Publikováno v:
Advances in Hematology, Vol 2022 (2022)
Advances in Hematology
Advances in Hematology
Ibrutinib-based therapies are costly and require continuous administration. We hypothesized combining BTK inhibition with anti-CD20 monoclonal antibodies would yield deep remissions allowing discontinuation. We enrolled 32 therapy-naïve CLL patients
Autor:
Mohamed A. Kharfan-Dabaja, Allison C. Rosenthal, Paula A. Lengerke-Diaz, Zaid Abdel Rahman, Jose Vicente Forero-Forero, Januario E. Castro, Eider F. Moreno-Cortes, Megan Melody
Publikováno v:
Hematology/oncology and stem cell therapy.
Objective/background Despite the success of chimeric antigen receptor (CAR) T-cell therapy in patients with aggressive non-Hodgkin lymphoma (aNHL), some patients still fail treatment, and their prognosis is dismal. Methods We performed a retrospectiv
Autor:
Fabián Jaimes, Juan José Hurtado-Guerra, Carolina Hincapié-Osorno, José Roberto Uribe-Delgado, Paula A. Lengerke-Diaz, Juan Sebastián Peinado-Acevedo, Santiago Giraldo-Ramírez, Juanita Mesa-Abad
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 74(1)
Autor:
Hemant S. Murthy, James M. Foran, Tuan Truong, Nicole Gannon, Eva Brandes, Mattia Novo, Paula A. Lengerke-Diaz, Allison C. Rosenthal, Vivek Roy, S. M. Ansell, Patrick B. Johnston, Gina Lange, Jonas Paludo, Yi Lin, Januario E. Castro, Mohamed A. Kharfan-Dabaja, Jose Villasboas Bisneto, N. Nora Bennani, Sangeetha Gandhi, Zaid Abdel Rahman, Breana Estby, Megan Melody, Ernesto Ayala, Han W. Tun
Publikováno v:
European journal of haematologyREFERENCES. 107(1)
Introduction Hypoalbuminemia is a known adverse prognostic factor in lymphomas. Yet, it is unknown if Axicabtagene Ciloleucel (axi-cel) overcomes the adverse prognostic impact of hypoalbuminemia in relapsed/refractory large B-cell lymphoma. Methods W
Autor:
Pramod Guru, Megan Melody, James M. Foran, Allison C. Rosenthal, Paula A Lengerke Diaz, Nicole Gannon, Mohamed A. Kharfan-Dabaja, Ernesto Ayala, Hemant S. Murthy, Vivek Roy, Hollie Saunders, Zaid Abdel Rahman, Han W. Tun, Januario E. Castro
Publikováno v:
Hematology/Oncology and Stem Cell Therapy, Vol 14, Iss 2, Pp 141-146 (2021)
Objective/Background Chimeric antigen receptor (CAR) T-cell is an effective therapy in relapsed/refractory large B-cell lymphomas that, due to its unique toxicities, often requires escalation of care to the intensive care unit (ICU) setting. C-reacti