Zobrazeno 1 - 10
of 563
pro vyhledávání: '"Paula T. Hammond"'
Autor:
Nicholas G. Lamson, Andrew J. Pickering, Jeffrey Wyckoff, Priya Ganesh, Elizabeth A. Calle, Joelle P. Straehla, Paula T. Hammond
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 4, Pp n/a-n/a (2024)
Abstract Drug‐carrying nanoparticles are a promising strategy to deliver therapeutics into the brain, but their translation requires better characterization of interactions between nanomaterials and endothelial cells of the blood–brain barrier (B
Externí odkaz:
https://doaj.org/article/02127fd78b2d417a89e33a918f78b3dd
Autor:
Dicky Pranantyo, Chun Kiat Yeo, Yang Wu, Chen Fan, Xiaofei Xu, Yun Sheng Yip, Marcus Ivan Gerard Vos, Surendra H. Mahadevegowda, Priscilla Lay Keng Lim, Liang Yang, Paula T. Hammond, David Ian Leavesley, Nguan Soon Tan, Mary B. Chan-Park
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Chronic wounds are often infected with biofilm bacteria and characterized by high oxidative stress. Current dressings that promote chronic wound healing either require additional processes such as photothermal irradiation or leave behind gro
Externí odkaz:
https://doaj.org/article/14bf74e861fc4aaaaf6145eb4697ebb6
Autor:
Stephanie Kong, Pearl Moharil, Abram Handly‐Santana, Natalie Boehnke, Richard Panayiotou, Victoria Gomerdinger, Gil Covarrubias, Ivan S. Pires, Ioannis Zervantonakis, Joan Brugge, Paula T. Hammond
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract The majority of patients with high grade serous ovarian cancer (HGSOC) develop recurrent disease and chemotherapy resistance. To identify drug combinations that would be effective in treatment of chemotherapy resistant disease, we examined t
Externí odkaz:
https://doaj.org/article/0fdb0c64b4324a05901ffd1980280b58
Autor:
Antonio E. Barberio, Sean G. Smith, Ivan S. Pires, Sonia Iyer, Ferenc Reinhardt, Mariane B. Melo, Heikyung Suh, Robert A. Weinberg, Darrell J. Irvine, Paula T. Hammond
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract Ovarian cancer is especially deadly, challenging to treat, and has proven refractory to known immunotherapies. Cytokine therapy is an attractive strategy to drive a proinflammatory immune response in immunologically cold tumors such as many
Externí odkaz:
https://doaj.org/article/da7a5559c1a94ad19eb3527ed8b1cd25
Autor:
Natalie Boehnke, Paula T. Hammond
Publikováno v:
JACS Au, Vol 2, Iss 1, Pp 12-21 (2021)
Externí odkaz:
https://doaj.org/article/03de81348ccc44e59fb5cf7717eed93d
Autor:
Sabine Steinbach, Sasan Jalili-Firoozinezhad, Sreenidhi Srinivasan, Mariane B. Melo, Sonya Middleton, Timm Konold, Michael Coad, Paula T. Hammond, Darrell J. Irvine, Martin Vordermeier, Vivek Kapur
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Bovine tuberculosis (bTB) is a disease of livestock with severe and worldwide economic, animal welfare and zoonotic consequences. Application of test-and-slaughter-based control polices reliant on tuberculin skin testing has been the mainsta
Externí odkaz:
https://doaj.org/article/3508ccbc973349b3af867acbcdaae274
Autor:
Yingzhong Li, Nikola A. Ivica, Ting Dong, Dimitrios P. Papageorgiou, Yanpu He, Douglas R. Brown, Marianna Kleyman, Guangan Hu, Walter W. Chen, Lucas B. Sullivan, Amanda Del Rosario, Paula T. Hammond, Matthew G. Vander Heiden, Jianzhu Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Mitochondria maintain a balance between thermogenesis and ATP synthesis, but how this is coordinated is largely unknown. Here, the authors show that MFSD7C coordinates ATP synthesis and thermogenesis in response to heme by directly binding to electro
Externí odkaz:
https://doaj.org/article/f4b39f9789c94baca207b22daeaf19cc
Autor:
Yi Wen Kong, Erik C. Dreaden, Sandra Morandell, Wen Zhou, Sanjeev S. Dhara, Ganapathy Sriram, Fred C. Lam, Jesse C. Patterson, Mohiuddin Quadir, Anh Dinh, Kevin E. Shopsowitz, Shohreh Varmeh, Ömer H. Yilmaz, Stephen J. Lippard, H. Christian Reinhardt, Michael T. Hemann, Paula T. Hammond, Michael B. Yaffe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Cell cycle checkpoint kinase, MK2, is in synthetic relationship with p53 in the DNA damage response to chemotherapeutic agents. Here, the authors report XPA as a third gene in which simultaneous targeting of MK2 and XPA further enhances sensitivity t
Externí odkaz:
https://doaj.org/article/968af14e7f93410d8098ad17f0bc993d
Autor:
Kaixi Zhang, Yu Du, Zhangyong Si, Yang Liu, Michelle E. Turvey, Cheerlavancha Raju, Damien Keogh, Lin Ruan, Subramanion L. Jothy, Sheethal Reghu, Kalisvar Marimuthu, Partha Pratim De, Oon Tek Ng, José R. Mediavilla, Barry N. Kreiswirth, Yonggui Robin Chi, Jinghua Ren, Kam C. Tam, Xue-Wei Liu, Hongwei Duan, Yabin Zhu, Yuguang Mu, Paula T. Hammond, Guillermo C. Bazan, Kevin Pethe, Mary B. Chan-Park
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The authors report the synthesis of an enantiomeric block co-beta-peptide that kills methicillin-resistant Staphylococcus aureus, including biofilm and persister bacterial cells, and disperses biofilms. The copolymer displays antibacterial activity i
Externí odkaz:
https://doaj.org/article/fe549d39d8134e549baba3508cc6c30c
Autor:
Morgan B. Ludwicki, Jiahe Li, Erin A. Stephens, Richard W. Roberts, Shohei Koide, Paula T. Hammond, Matthew P. DeLisa
Publikováno v:
ACS Central Science, Vol 5, Iss 5, Pp 852-866 (2019)
Externí odkaz:
https://doaj.org/article/0192f621174940d7b673e9ba5021607e