Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Paula Berghofer"'
Autor:
Ivan Ho Shon, Divesh Kumar, Chithradevi Sathiakumar, Paula Berghofer, Khang Van, Andrew Chicco, Philip J. Hogg
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid (GSAO) when conjugated at the γ-glutamyl residue with fluorophores and radio-isotopes is able to image dead and dying cells in vitro and in vivo by binding to intracellular 90
Externí odkaz:
https://doaj.org/article/2990945884f94eff9ed7380329beaa1e
Autor:
Tien Pham, Naomi Wyatt, Ivan Greguric, Thanh Le, Michael J. Fulham, Filomena Mattner, Christopher J. R. Fookes, Andrew Katsifis, Timothy Jackson, Christian Loc'h, Tzong-Tyng Hung, Jackson Poon, Brendan Lee, Rachael Shepherd, David Henderson, Carl Power, Thomas Bourdier, Paula Berghofer
Publikováno v:
RSC Medicinal Chemistry. 12:1207-1221
Radiopharmaceuticals that target the translocator protein 18 kDa (TSPO) have been investigated with positron emission tomography (PET) to study neuroinflammation, neurodegeneration and cancer. We have developed the novel, achiral, 2-phenylimidazo[1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6624d71d8b68023aa408199d6bd3d34
https://doi.org/10.1039/d1md00035g
https://doi.org/10.1039/d1md00035g
Autor:
Filomena, Mattner, Andrew, Katsifis, Thomas, Bourdier, Christian, Loc'h, Paula, Berghofer, Christopher, Fookes, Tzong-Tyng, Hung, Timothy, Jackson, David, Henderson, Tien, Pham, Brendan J, Lee, Rachael, Shepherd, Ivan, Greguric, Naomi, Wyatt, Thanh, Le, Jackson, Poon, Carl, Power, Michael, Fulham
Publikováno v:
RSC Med Chem
Radiopharmaceuticals that target the translocator protein 18 kDa (TSPO) have been investigated with positron emission tomography (PET) to study neuroinflammation, neurodegeneration and cancer. We have developed the novel, achiral, 2-phenylimidazo[1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6344cf3c03eabeef7d23abcf73f3331
https://pubmed.ncbi.nlm.nih.gov/34355185
https://pubmed.ncbi.nlm.nih.gov/34355185
Autor:
Philip J. Hogg, Divesh Kumar, Paula Berghofer, Andrew Chicco, Ivan Ho Shon, Khang Van, Chithradevi Sathiakumar
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
EJNMMI Research
EJNMMI Research
Background 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid (GSAO) when conjugated at the γ-glutamyl residue with fluorophores and radio-isotopes is able to image dead and dying cells in vitro and in vivo by binding to intracellular 90-kDa heat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ecf463b1a4dab9cf1b809259c25b441
https://doi.org/10.1186/s13550-020-0590-x
https://doi.org/10.1186/s13550-020-0590-x
Autor:
Benjamin H. Fraser, Ivan Greguric, Cathy D. Jiang, Anwen M. Krause-Heuer, Leena Hogan, Lidia Matesic, Andrew Katsifis, Vu Nguyen, Rodney J. Hicks, Marie-Claude Gregoire, Tien Q. Pham, Paula Berghofer, Delphine Denoyer, Maxine P. Roberts, Nigel A. Lengkeek, Stephen R. Taylor, Mark E. Ashford, Naomi Wyatt
Publikováno v:
Journal of Medicinal Chemistry. 58:6214-6224
This study reports the synthesis, [(123)I]radiolabeling, and biological profile of a new series of iodinated compounds for potential translation to the corresponding [(131)I]radiolabeled compounds for radionuclide therapy of melanoma. Radiolabeling w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9898816115aebcd799c2e3538e483b
https://doi.org/10.1021/acs.jmedchem.5b00777
https://doi.org/10.1021/acs.jmedchem.5b00777
Autor:
David Zahra, Timothy Jackson, Tien Pham, Gita Rahardjo, David Linares, Heng Jian Wong, Filomena Mattner, Paul D. Callaghan, Susan Fordham, Maria A. Staykova, Paula Berghofer, Andrew Katsifis, Marie-Claude Gregoire
Publikováno v:
Journal of Nuclear Medicine. 54:291-298
Glial neuroinflammation is associated with the development and progression of multiple sclerosis. PET imaging offers a unique opportunity to evaluate neuroinflammatory processes longitudinally in a noninvasive and clinically translational manner. 18F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edc4b0e8a02f6dbc989ee39b7924919
https://doi.org/10.2967/jnumed.112.108894
https://doi.org/10.2967/jnumed.112.108894
Autor:
Marie-Claude Gregoire, Paula Berghofer, David Linares Bandin, David O. Willenborg, Andrew Katsifis, Tien Pham, Maria A. Staykova, Mitchell Quinlivan, Patrice Ballantyne, Susan Fordham, Filomena Mattner
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 38:1516-1528
The purpose of this study was to assess the feasibility and sensitivity of the high-affinity translocator protein (TSPO) ligand [123I]-CLINDE in imaging TSPO changes in vivo and characterise and compare astroglial and TSPO changes in the cuprizone mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e55023577e2fc00150e578c2d9d95f48
https://doi.org/10.1007/s00259-011-1784-2
https://doi.org/10.1007/s00259-011-1784-2
Autor:
Donna S. Dorow, Thomas Bourdier, Christopher J. R. Fookes, Timothy Jackson, Delphine Denoyer, Rachael Shepherd, Andrew Katsifis, Paula Berghofer, Marie-Claude Gregoire, Rodney J. Hicks, Ivan Greguric
Publikováno v:
Journal of Medicinal Chemistry. 54:1860-1870
Interest in radiolabeled amino acids for metabolic imaging of cancer and limitations with [(11)C]methionine has prompted the development of a new (18)F-labeled methionine derivative S-(3-[(18)F]fluoropropyl)homocysteine ([(18)F]FPHCys). The L and D e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78988d611c44b947c86c79fbd74acccb
https://doi.org/10.1021/jm101513q
https://doi.org/10.1021/jm101513q
Autor:
Christopher J. R. Fookes, Filomena Mattner, Marie-Claude Gregoire, Branko Dikic, Mitchell Quinlivan, Frédéric Dollé, Paula Berghofer, Xiang Liu, Andrew Katsifis, Ivan Greguric, T. Pham, Terri Jackson
Publikováno v:
Disease Markers
Disease Markers, Vol 2015 (2015)
Disease Markers, Vol 2015 (2015)
The high affinity translocator protein (TSPO) ligand 6-chloro-2-(4′-iodophenyl)-3-(N,N-methylethyl)imidazo[1,2-a]pyridine-3-acetamide (CLINME) was radiolabelled with iodine-123 and assessed for its sensitivity for the TSPO in rodents. Moreover neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ca4bae95ff0b7f46f856ba7eb071b1
http://europepmc.org/articles/PMC4496498
http://europepmc.org/articles/PMC4496498
Autor:
Filomena Mattner, Gita Rahardjo, Marie-Claude Gregoire, Paul D. Callaghan, Halima Amhaoul, Mitchell Quinlivan, Christian Loc'h, Andrew Katsifis, Paula Berghofer, Tien Pham, Stefanie Dedeurwaerdere
Publikováno v:
EJNMMI research
EJNMMI Research
EJNMMI Research
Background Recently, inflammatory cascades have been suggested as a target for epilepsy therapy. Positron emission tomography (PET) imaging offers the unique possibility to evaluate brain inflammation longitudinally in a non-invasive translational ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c014f65e8e4b4bdbd53165fe68b4482
https://hdl.handle.net/10067/1064110151162165141
https://hdl.handle.net/10067/1064110151162165141