Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Paul-Rémi Pétit"'
Autor:
Jean-Sélim Driouich, Maxime Cochin, Guillaume Lingas, Léa Luciani, Cécile Baronti, Ornéllie Bernadin, Magali Gilles, Paola Mariela Saba Villarroel, Grégory Moureau, Paul-Rémi Petit, Axelle Dupont, Jacques Izopet, Nassim Kamar, Brigitte Autran, Gilles Paintaud, Sophie Caillard, Amandine le Bourgeois, Christophe Richez, Lionel Couzi, Aliénor Xhaard, Zora Marjanovic, Jerome Avouac, Caroline Jacquet, Dany Anglicheau, Morgane Cheminant, Stéphanie Nguyen, Benjamin Terrier, Jacques Eric Gottenberg, Caroline Besson, Sophie Letrou, Josephine Tine, Joe Miantezila Basilua, Denis Angoulvant, Coralie Tardivon, Gilles Blancho, Guillaume Martin-Blondel, Yazdan Yazdanpanah, France Mentré, Vincent Lévy, Franck Touret, Jérémie Guedj, Xavier de Lamballerie, Antoine Nougairède
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116988- (2024)
Therapeutic monoclonal antibodies have been successful in protecting vulnerable populations against SARS-CoV-2. However, their effectiveness has been hampered by the emergence of new variants. To adapt the therapeutic landscape, health authorities ha
Externí odkaz:
https://doaj.org/article/37d8355502934219aae7717aaa15b4b4
Autor:
Paul-Rémi Petit, Franck Touret, Jean-Sélim Driouich, Maxime Cochin, Léa Luciani, Ornéllie Bernadin, Caroline Laprie, Géraldine Piorkowski, Laurent Fraisse, Peter Sjö, Charles E. Mowbray, Fanny Escudié, Ivan Scandale, Eric Chatelain, Xavier de Lamballerie, Caroline Solas, Antoine Nougairède
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e30862- (2024)
The SARS-CoV-2 pandemic has highlighted the need for broad-spectrum antiviral drugs to respond promptly to viral emergence. We conducted a preclinical study of molnupiravir (MOV) against SARS-CoV-2 to fully characterise its antiviral properties and m
Externí odkaz:
https://doaj.org/article/1a39566e56e64bfcb9d0d5134525713d
Autor:
Maxime Cochin, Léa Luciani, Franck Touret, Jean-Sélim Driouich, Paul-Rémi Petit, Grégory Moureau, Cécile Baronti, Caroline Laprie, Laurence Thirion, Piet Maes, Robbert Boudewijns, Johan Neyts, Xavier de Lamballerie, Antoine Nougairède
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
The SARS-CoV-2 Alpha variant exhibits similar transmission dynamics to an ancestral D614G variant in a Syrian hamster model, suggesting the limitations of using the hamster as the sole model to assess differences between SARS-CoV-2 strains.
Externí odkaz:
https://doaj.org/article/768ee2ace9a649e5907824f60e628b09
Autor:
Jean-Sélim Driouich, Maxime Cochin, Franck Touret, Paul-Rémi Petit, Magali Gilles, Grégory Moureau, Karine Barthélémy, Caroline Laprie, Thanaporn Wattanakul, Palang Chotsiri, Richard M. Hoglund, Joel Tarning, Laurent Fraisse, Peter Sjö, Charles E. Mowbray, Fanny Escudié, Ivan Scandale, Eric Chatelain, Xavier de Lamballerie, Caroline Solas, Antoine Nougairède
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104148- (2022)
Summary: Background: To address the emergence of SARS-CoV-2, multiple clinical trials in humans were rapidly started, including those involving an oral treatment by nitazoxanide, despite no or limited pre-clinical evidence of antiviral efficacy. Meth
Externí odkaz:
https://doaj.org/article/2c868ce6fdee4c09b5bfe87564b64a94
Autor:
Jean-Sélim Driouich, Maxime Cochin, Guillaume Lingas, Grégory Moureau, Franck Touret, Paul-Rémi Petit, Géraldine Piorkowski, Karine Barthélémy, Caroline Laprie, Bruno Coutard, Jérémie Guedj, Xavier de Lamballerie, Caroline Solas, Antoine Nougairède
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Favipiravir has broad-spectrum antiviral activity against a variety of RNA viruses. Here the authors investigate the safety, pharmacokinetics and anti-SARS-CoV-2 efficacy of different drug dosage in the a Syrian hamster model of infection and, combin
Externí odkaz:
https://doaj.org/article/28b65fe72e8643d09a5316e736cd7471
Autor:
Amandine Bonifay, Stéphane Robert, Belinda Champagne, Paul‐Rémi Petit, Aude Eugène, Corinne Chareyre, Anne‐Claire Duchez, Mélanie Vélier, Shirley Fritz, Loris Vallier, Romaric Lacroix, Françoise Dignat‐George
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 4, Pp n/a-n/a (2022)
Abstract Newly recognized polymorphonuclear neutrophil (PMNs) functions include the ability to release subcellular mediators such as neutrophil‐derived extracellular vesicles (NDEVs) involved in immune and thrombo‐inflammatory responses. Elevatio
Externí odkaz:
https://doaj.org/article/12117ce56d534d6fac6a5cdf99098b32
Autor:
Frauke Assmus, Jean-Sélim Driouich, Rana Abdelnabi, Laura Vangeel, Franck Touret, Ayorinde Adehin, Palang Chotsiri, Maxime Cochin, Caroline S. Foo, Dirk Jochmans, Seungtaek Kim, Léa Luciani, Grégory Moureau, Soonju Park, Paul-Rémi Pétit, David Shum, Thanaporn Wattanakul, Birgit Weynand, Laurent Fraisse, Jean-Robert Ioset, Charles E. Mowbray, Andrew Owen, Richard M. Hoglund, Joel Tarning, Xavier de Lamballerie, Antoine Nougairède, Johan Neyts, Peter Sjö, Fanny Escudié, Ivan Scandale, Eric Chatelain
Publikováno v:
Microorganisms, Vol 10, Iss 8, p 1639 (2022)
In the absence of drugs to treat or prevent COVID-19, drug repurposing can be a valuable strategy. Despite a substantial number of clinical trials, drug repurposing did not deliver on its promise. While success was observed with some repurposed drugs
Externí odkaz:
https://doaj.org/article/a9ef2617e75845fa98746d7ddae47ef7