Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Paul-Martin Holterhus"'
Autor:
Paul-Martin Holterhus, Alexandra Kulle, Anne-Marie Till, Caroline Stille, Tabea Lamprecht, Simon Vieth, Melchior Lauten
Publikováno v:
Endocrine Connections, Vol 12, Iss 10, Pp 1-9 (2023)
Glucocorticoids represent a key element in the treatment of pediatric acute lymphoblastic leukemia (ALL) and lead to adrenal suppression. We aimed to ass ess the differential response profile of adrenal steroids in children with ALL during BFM (Berli
Externí odkaz:
https://doaj.org/article/363ce623c03b4cc99298d6cffbd4ad47
Autor:
Tim Cheetham, Sukran Poyrazoglu, Justin H Davies, S Faisal Ahmed, Jillian Bryce, Anna Nordenström, Angela K Lucas-Herald, Paul-Martin Holterhus, Marcio Lopes Miranda, Stuart O’Toole, Eduardo Corrêa Costa, Kathryn Scougall, Federico Baronio, Rachel L Boal, Jose Roberto Castera, Sebastián Castro, Feyza Darendeliler, Mirjam Dirlewanger, Gabriella Gazdagh, Evgenia Globa, Gil Guerra-Junior, Tulay Guran, Gloria Herrmann, Ahsen Karagözlü Akgül, Renata Markosyan, Kenneth McElreavey, Gianni Russo, Valerie Schwitzgebel, Marianna Stancampiano, Michael Steigert
Publikováno v:
World Journal of Pediatric Surgery, Vol 6, Iss 4 (2023)
Background Complications are frequently reported after hypospadias repair and there is a need to understand the factors that influence their occurrence.Methods Data from boys with hypospadias born between 2000 and 2020 were obtained from the Internat
Externí odkaz:
https://doaj.org/article/b2a11fe3b8a642f185956951b5a23a49
Autor:
Luca Persani, Martine Cools, Stamatina Ioakim, S Faisal Ahmed, Silvia Andonova, Magdalena Avbelj-Stefanija, Federico Baronio, Jerome Bouligand, Hennie T Bruggenwirth, Justin H Davies, Elfride De Baere, Iveta Dzivite-Krisane, Paula Fernandez-Alvarez, Alexander Gheldof, Claudia Giavoli, Claus H Gravholt, Olaf Hiort, Paul-Martin Holterhus, Anders Juul, Csilla Krausz, Kristina Lagerstedt-Robinson, Ruth McGowan, Uta Neumann, Antonio Novelli, Xavier Peyrassol, Leonidas A Phylactou, Julia Rohayem, Philippe Touraine, Dineke Westra, Valeria Vezzoli, Raffaella Rossetti
Publikováno v:
Endocrine Connections, Vol 11, Iss 22, Pp 1-7 (2022)
Differences of sex development and maturation (SDM) represent a heterogeneous puzzle of rare conditions with a large genetic component whose management and treatment could be improved by an accurate classification of underlying molecular conditions,
Externí odkaz:
https://doaj.org/article/2d8fa80d5d96414aaaa8f97a72aee4ac
Autor:
Raphael Hirtz, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, Cordula Kiewert, Berthold P. Hauffa, Johannes Hebebrand, Corinna Grasemann
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract There is preliminary evidence that adrenal steroids other than cortisol may be valuable biomarkers for major depressive disorder (MDD). So far, studies have been conducted in adults only, and conclusions are limited, mainly due to small samp
Externí odkaz:
https://doaj.org/article/0d71ada72cf64eccaa657707a0a37a43
Autor:
Michaela Kuhlen, Pascal Mier, Marina Kunstreich, Lienhard Lessel, Christoph Slavetinsky, Jörg Fuchs, Guido Seitz, Paul-Martin Holterhus, Stefan A. Wudy, Christian Vokuhl, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
Cancers, Vol 15, Iss 17, p 4296 (2023)
Background: Locally advanced tumors account for approximately 50% of children and adolescents with adrenocortical carcinoma (ACC), and of these, up to 50% relapse. We explored the five-item microscopic score and the pS-GRAS score for guiding manageme
Externí odkaz:
https://doaj.org/article/bc4fb899e0ca4f959db57ea9c052d085
Autor:
Michaela Kuhlen, Marina Kunstreich, Lienhard Lessel, Stefan A. Wudy, Paul-Martin Holterhus, Christian Vokuhl, Eva Juettner, Christoph Roecken, Guido Seitz, Christoph Slavetinsky, Jörg Fuchs, Denis M. Schewe, Rainer Claus, Pascal D. Johann, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
EJC Paediatric Oncology, Vol 1, Iss , Pp 100015- (2023)
Background: Paediatric adrenocortical carcinomas (ACC) are highly aggressive malignancies with a dismal prognosis in advanced and metastatic diseases. Little is known about outcome of patients with refractory and relapsed (r/r) disease. Procedure: Na
Externí odkaz:
https://doaj.org/article/87befb459f374e449313ef4fba15ab29
Autor:
Isabel Viola Wagner, Iuliia Savchuk, Lena Sahlin, Alexandra Kulle, Nora Klöting, Arne Dietrich, Paul-Martin Holterhus, Jörg Dötsch, Matthias Blüher, Olle Söder
Publikováno v:
Obesity Facts, Pp 1-11 (2022)
Introduction: Obesity in women is often associated with hyperandrogenism, but the role of adipose tissue (AT) in androgen synthesis remains unclear. Therefore, we studied whether AT could be a source of androgens promoting hyperandrogenism. Methods:
Externí odkaz:
https://doaj.org/article/69223357e2cd4ad08c087fba0ebd1ec8
Autor:
Michaela Kuhlen, Marina Kunstreich, Stefan A. Wudy, Paul-Martin Holterhus, Lienhard Lessel, Dominik T. Schneider, Ines B. Brecht, Denis M. Schewe, Guido Seitz, Christoph Roecken, Christian Vokuhl, Pascal D. Johann, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
Cancers, Vol 15, Iss 1, p 225 (2022)
Background: Adrenocortical tumors (ACTs) encompassing the adrenocortical adenoma (ACA), carcinoma (ACC), and tumors of undetermined malignant potential (ACx) are rare endocrine neoplasms with a poor prognosis. We report on pediatric ACT patients regi
Externí odkaz:
https://doaj.org/article/98e5b64074ad49bca53b848681b451a0
Autor:
Vera Splittstösser, Felix Schreiner, Bettina Gohlke, Maik Welzel, Paul-Martin Holterhus, Joachim Woelfle
Publikováno v:
BMC Endocrine Disorders, Vol 19, Iss 1, Pp 1-4 (2019)
Abstract Background We report a novel mutation within the StAR gene, causing congenital adrenal hyperplasia, with the so far unreported association with heterochromia iridis. Case presentation In a now 15-year-old girl (born at 41 + 6 weeks of gestat
Externí odkaz:
https://doaj.org/article/bdb3593dceb441aab1d0be6d379e0c4c
Autor:
Raphael Hirtz, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, Cordula Kiewert, Johannes Hebebrand, Corinna Grasemann
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
There is a distinct increase in the prevalence of depression with the onset of puberty. The role of peripubertal testosterone levels in boys in this context is insufficiently understood and may be modulated by a functional polymorphism of the androge
Externí odkaz:
https://doaj.org/article/d4cedb4db6444c35ab23d35e5c2680ab