Výsledky vyhledávání - "Paul-Clark M"

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The Role of Vascular-Immune Interactions in Modulating Chemotherapy Induced Neuropathic Pain

Autor: Valentine, T, Hardowar, L, Elphick-Ross, J, Hulse, RP, Paul-Clark, M

Publikováno v: Frontiers in pharmacology. 13

Chemotherapy causes sensory disturbances in cancer patients that results in neuropathies and pain. As cancer survivorships has dramatically increased over the past 10 years, pain management of these patients is becoming clinically more important. Cur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060542ecfc5fc6c79c5ca00d8a21e1e6
https://pubmed.ncbi.nlm.nih.gov/35814225

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Differential role of the pannexin-1/ATP/P2X7 axis in IL-1β release by human monocytes

Autor: Parzych, K, Zetterqvist, A, Wright, WR, Kirkby, NS, Mitchell, JA, Paul-Clark, M

IL - 1 β release is integral to the innate immune system. The release of mature IL - 1 β depends on two regulated events; (i) the de novo induction of pro - IL - 1 β , generally via NF κ B - depend ent transduction pathways and (ii) the assembly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::36c577fc417d058304ee3703841b1877
http://hdl.handle.net/10044/1/44393

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Akademický článek

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Akademický článek

Cigarette smoke inhibits macrophage sensing of Gram-negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress.

Autor: McMaster, S. K.¹, Paul-Clark, M. J.¹, Walters, M.², Fleet, M.¹, Anandarajah, J.¹, Sriskandan, S.³, Mitchell, J. A.¹ j.a.mitchell@ic.ac.uk or Dr Mark Paul-Clark

Publikováno v: British Journal of Pharmacology. Feb2008, Vol. 153 Issue 3, p536-543. 8p. 1 Chart, 8 Graphs.

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Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages

Autor: Moreno, L, McMaster, SK, Gatheral, T, Bailey, LK, Harrington, LS, Cartwright, N, Armstrong, PCJ, Warner, TD, Paul-Clark, M, Mitchell, JA

Publikováno v: British Journal of Pharmacology

Background and purpose: Gram-negative bacteria contain ligands for Toll-like receptor (TLR) 4 and nucleotide oligomerization domain (NOD) 1 receptors. Lipopolysaccharide (LPS) activates TLR4, while peptidoglycan products activate NOD1. Activation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ec78538009c76e61e43afa30a06c2e9
http://europepmc.org/articles/PMC2913099

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Cigarette smoke inhibits macrophage sensing of Gram-negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress

Autor: McMaster, S K, Paul-Clark, M J, Walters, M, Fleet, M, Anandarajah, J, Sriskandan, S, Mitchell, J A

Smoking cigarettes is a major risk factor for the development of cardiovascular and respiratory disease. Moreover, smokers are more prone to infections. This has been associated with a suppression of the immune system by smoke. However, it is not cle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eaecda548cf062408cf9ce4a2bbf3ed4
https://europepmc.org/articles/PMC2241791/

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