Výsledky vyhledávání - "Paul-Clark M"

Akademický článek

Early-life cisplatin exposure induces neuroinflammation and chemotherapy-induced neuropathic pain.

Autor: Da Vitoria Lobo M; Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK., Hardowar L; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK., Valentine T; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK., Tomblin L; Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK., Guest C; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK., Sharma D; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK., Dickins B; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK., Paul-Clark M; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK., Hulse RP; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2024 Nov 01; Vol. 17 (11). Date of Electronic Publication: 2024 Nov 27.

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Author Correction: Development of a novel UHPLC-MS/MS-based platform to quantify amines, amino acids and methylarginines for applications in human disease phenotyping.

Autor: Ahmetaj-Shala B; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK. b.ahmetaj@imperial.ac.uk., Olanipekun M; Department of Surgery and Cancer, Imperial College London, London, SW7 2BB, UK., Tesfai A; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., MacCallum N; Critical Care, University College London Hospital, London, NW1 2BU, UK., Kirkby NS; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Quinlan GJ; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Shih CC; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Kawai R; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Mumby S; Respiratory, Airway Disease, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Paul-Clark M; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK., Want EJ; Department of Surgery and Cancer, Imperial College London, London, SW7 2BB, UK. e.want@imperial.ac.uk., Mitchell JA; Cardiothoracic Pharmacology, Vascular Biology, National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK. j.a.mitchell@ic.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2024 May 23; Vol. 14 (1), pp. 11800. Date of Electronic Publication: 2024 May 23.

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The Role of Vascular-Immune Interactions in Modulating Chemotherapy Induced Neuropathic Pain

Autor: Valentine, T, Hardowar, L, Elphick-Ross, J, Hulse, RP, Paul-Clark, M

Publikováno v: Frontiers in pharmacology. 13

Chemotherapy causes sensory disturbances in cancer patients that results in neuropathies and pain. As cancer survivorships has dramatically increased over the past 10 years, pain management of these patients is becoming clinically more important. Cur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060542ecfc5fc6c79c5ca00d8a21e1e6
https://pubmed.ncbi.nlm.nih.gov/35814225

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Akademický článek

Cigarette smoke inhibits macrophage sensing of Gram-negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress.

Autor: McMaster, S. K.¹, Paul-Clark, M. J.¹, Walters, M.², Fleet, M.¹, Anandarajah, J.¹, Sriskandan, S.³, Mitchell, J. A.¹ j.a.mitchell@ic.ac.uk or Dr Mark Paul-Clark

Publikováno v: British Journal of Pharmacology. Feb2008, Vol. 153 Issue 3, p536-543. 8p. 1 Chart, 8 Graphs.

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Differential role of the pannexin-1/ATP/P2X7 axis in IL-1β release by human monocytes

Autor: Parzych, K, Zetterqvist, A, Wright, WR, Kirkby, NS, Mitchell, JA, Paul-Clark, M

IL - 1 β release is integral to the innate immune system. The release of mature IL - 1 β depends on two regulated events; (i) the de novo induction of pro - IL - 1 β , generally via NF κ B - depend ent transduction pathways and (ii) the assembly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::36c577fc417d058304ee3703841b1877
http://hdl.handle.net/10044/1/44393

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Akademický článek

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Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages

Autor: Moreno, L, McMaster, SK, Gatheral, T, Bailey, LK, Harrington, LS, Cartwright, N, Armstrong, PCJ, Warner, TD, Paul-Clark, M, Mitchell, JA

Publikováno v: British Journal of Pharmacology

Background and purpose: Gram-negative bacteria contain ligands for Toll-like receptor (TLR) 4 and nucleotide oligomerization domain (NOD) 1 receptors. Lipopolysaccharide (LPS) activates TLR4, while peptidoglycan products activate NOD1. Activation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ec78538009c76e61e43afa30a06c2e9
http://europepmc.org/articles/PMC2913099

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Akademický článek

EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype.

Autor: Ciano M; Department of Medicine, Imperial College London, London, UK., Mantellato G; National Heart and Lung Institute, Imperial College London, London, UK., Connolly M; National Heart and Lung Institute, Imperial College London, London, UK., Paul-Clark M; National Heart and Lung Institute, Imperial College London, London, UK., Willis-Owen S; National Heart and Lung Institute, Imperial College London, London, UK., Moffatt MF; National Heart and Lung Institute, Imperial College London, London, UK., Cookson WOCM; National Heart and Lung Institute, Imperial College London, London, UK., Mitchell JA; National Heart and Lung Institute, Imperial College London, London, UK., Polkey MI; Royal Brompton and Harefield NHS Foundation Trust, London, UK., Hughes SM; Randall Division of Cell & Molecular Biophysics, King's College London, London, UK., Kemp PR; National Heart and Lung Institute, Imperial College London, London, UK., Natanek SA; National Heart and Lung Institute, Imperial College London, London, UK. a.natanek@imperial.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2019 Jun 25; Vol. 9 (1), pp. 9218. Date of Electronic Publication: 2019 Jun 25.

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