Výsledky vyhledávání - "Paul Winjhoven"

Abstract 3505: AZD7648: A potent and selective inhibitor of DNA-PK with pharmacodynamic and monotherapy anti-tumor activity

Autor: Emma Dean, Antonio Ramos-Montoya, Elaine Cadogan, Jacqueline H. L. Fok, Lenka Oplustil O'Connor, Barry R. Davies, Neil H. James, Paul Winjhoven, Valeria Follia, Ankur Karmokar, Anna Staniszewska, Mercedes Vazquez-Chantada, Simon J. Hollingsworth

Publikováno v: Cancer Research. 79:3505-3505

DNA-dependent kinase (DNA-PK) is a nuclear serine/threonine protein kinase complex that is a key component of the non-homologous end joining (NHEJ) process. DNA-PK plays an important role in the cellular response to DNA damage through the detection a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3da36654f442068097cfc48c3d5f6e7
https://doi.org/10.1158/1538-7445.am2019-3505

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