Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paul Wellman"'
Autor:
Harsita Patel, Michael J. Carter, Heather Jackson, Oliver Powell, Matthew Fish, Manuela Terranova-Barberio, Filomena Spada, Nedyalko Petrov, Paul Wellman, Sarah Darnell, Sobia Mustafa, Katrina Todd, Cynthia Bishop, Jonathan M. Cohen, Julia Kenny, Sarah van den Berg, Thomas Sun, Francesca Davis, Aislinn Jennings, Emma Timms, Jessica Thomas, Maggie Nyirendra, Samuel Nichols, Leire Estamiana Elorieta, Giselle D’Souza, Victoria Wright, Tisham De, Dominic Habgood-Coote, Padmanabhan Ramnarayan, Pierre Tissières, Elizabeth Whittaker, Jethro Herberg, Aubrey Cunnington, Myrsini Kaforou, Richard Ellis, Michael H. Malim, Shane M. Tibby, Manu Shankar-Hari, Michael Levin, On behalf of the DIAMONDS Consortium
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Severe febrile illnesses in children encompass life-threatening organ dysfunction caused by diverse pathogens and other severe inflammatory syndromes. A comparative approach to these illnesses may identify shared and distinct features of hos
Externí odkaz:
https://doaj.org/article/d2c0c6faa08d407fae3fa0e21cb48076
Autor:
Heather Lambert, Shaun Hiu, Malcolm Coulthard, John N S Matthews, Ruth Wood, Jean Crosier, Rachel Agbeko, Thomas Brick, Heather Duncan, David Grant, Quen Mok, Andrew Gustaf Nyman, John Pappachan, Paul Wellman, Chris Boucher, Joe Bulmer, Denise Chisholm, Kirsten Cromie, Victoria Emmet, Richard Feltbower, Michael Grayling, Rebecca Harrison, Eva-Maria Holstein, Ciara A Kennedy, Elaine McColl, Kevin Morris, Lee Norman, Julie Office, Roger Parslow, Christine Pattinson, Shriya Sharma, Jonathan Smith, Alison Steel, Rachel Steel, Jayne Straker, Lamprini Vrana, Jenn Walker, Mike Whitaker, Jim Wightman, Nina Wilson, Lucy Wirz
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 11, Iss 01 (2024)
Abstract Background Critically unwell babies in intensive care units may develop acute renal failure. Options for renal replacement therapy are limited by their small size and available technology. Objectives To determine the clinical efficacy, outco
Externí odkaz:
https://doaj.org/article/954cf88ad8224311987f30e8bc5d1a16
Autor:
Mark J. Peters, Kerry Woolfall, Imran Khan, Elisabeth Deja, Paul R. Mouncey, Jerome Wulff, Alexina Mason, Rachel S. Agbeko, Elizabeth S. Draper, Blaise Fenn, Doug W. Gould, Abby Koelewyn, Nigel Klein, Christine Mackerness, Sian Martin, Lauran O’Neill, Samiran Ray, Padmanabhan Ramnarayan, Shane Tibby, Kentigern Thorburn, Lyvonne Tume, Jason Watkins, Paul Wellman, David A. Harrison, Kathryn M. Rowan, the FEVER Investigators on behalf of the Paediatric Intensive Care Society Study Group (PICS-SG)
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-11 (2019)
Abstract Background Fever improves pathogen control at a significant metabolic cost. No randomized clinical trials (RCT) have compared fever treatment thresholds in critically ill children. We performed a pilot RCT to determine whether a definitive t
Externí odkaz:
https://doaj.org/article/7f2ac693747c4d0881fc2592e54c02e6
Autor:
Mark J Peters, Imran Khan, Kerry Woolfall, Elizabeth Deja, Paul R Mouncey, Jerome Wulff, Alexina Mason, Rachel Agbeko, Elizabeth S Draper, Blaise Fenn, Doug W Gould, Abby Koelewyn, Nigel Klein, Christine Mackerness, Sian Martin, Lauran O’Neill, Padmanabhan Ramnarayan, Shane Tibby, Lyvonne Tume, Jason Watkins, Kent Thorburn, Paul Wellman, David A Harrison, Kathryn M Rowan
Publikováno v:
Health Technology Assessment, Vol 23, Iss 5 (2019)
Background: Fever accelerates host immune system control of pathogens but at a high metabolic cost. The optimal approach to fever management and the optimal temperature thresholds used for treatment in critically ill children are unknown. Objectives:
Externí odkaz:
https://doaj.org/article/a042a3fc55e94b9fb60a513b45ce1ec6
Autor:
Katherine L. Brown, Mohammed Moinuddin, Alison Jones, Karen Sheehan, Paul Wellman, Warren Rodrigues, Deborah Ridout, Jo Wray
Publikováno v:
Pediatric Critical Care Medicine. 24:194-203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd20c542533c4702725778f3600360e4
https://doi.org/10.1097/pcc.0000000000003137
https://doi.org/10.1097/pcc.0000000000003137
Autor:
Heather Lambert, Shaun Hiu, Malcolm G. Coulthard, John N. S. Matthews, Eva-Maria Holstein, Jean Crosier, Rachel Agbeko, Thomas Brick, Heather Duncan, David Grant, Quen Mok, Andrew Gustaf Nyman, John Pappachan, Chris Boucher, Joe Bulmer, Denise Chisholm, Kirsten Cromie, Victoria Emmet, Richard G. Feltbower, Arunoday Ghose, Michael Grayling, Rebecca Harrison, Ciara A. Kennedy, Elaine McColl, Kevin Morris, Lee Norman, Julie Office, Roger Parslow, Christine Pattinson, Shriya Sharma, Jonathan Smith, Alison Steel, Rachel Steel, Jayne Straker, Lamprini Vrana, Jenn Walker, Paul Wellman, Mike Whitaker, Jim Wightman, Nina Wilson, Lucy Wirz, Ruth Wood
Publikováno v:
Pediatric Critical Care Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1310dcbbac7676b43eee0f05af939b6a
https://doi.org/10.1097/pcc.0000000000003220
https://doi.org/10.1097/pcc.0000000000003220
Autor:
Jean Crosier, Mike Whitaker, Heather J. Lambert, Paul Wellman, Andrew Nyman, Malcolm G. Coulthard
Publikováno v:
Pediatric Nephrology. 37:3189-3194
Background To determine in vitro whether infant hemofiltration and hemodialysis devices can reliably deliver precise ultrafiltration (UF) control. Methods We tested the Prismaflex, Aquarius and NIDUS devices which have different circuit types, by in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d370b69d0bc99271e10d3ad718f8a55
https://doi.org/10.1007/s00467-022-05439-y
https://doi.org/10.1007/s00467-022-05439-y
Autor:
Katherine L Brown, Paul Wellman, Peter G Davis, Deborah Ridout, Alison L Jones, Christina Pagel, Jo Wray, Warren Rodrigues, Victor Tsang, Emma Hudson
Publikováno v:
The Annals of Thoracic Surgery
Background Most children now survive cardiac surgery, and the focus of quality improvement initiatives has shifted toward more complex outcome measures. The aim of this investigation was to study the impact of early postoperative morbidities on paren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52539deebb5b82a33cc9591d7673b51
https://doi.org/10.1016/j.athoracsur.2020.11.003
https://doi.org/10.1016/j.athoracsur.2020.11.003
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 45:1720-1728
BACKGROUND On a 20-bed, mixed cardiac and general, UK pediatric intensive care unit (PICU), we aimed to determine if a physiologically based enteral feeding guideline for critically ill children, using feed frequency tailored to individual gastric em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2170ffe535f516d605cfc858914f7f5d
https://doi.org/10.1002/jpen.2077
https://doi.org/10.1002/jpen.2077
Autor:
Katie J. Doores, Manu Shankar-Hari, Carl Graham, Paul Wellman, Matthew Fish, Shane M. Tibby, Aislinn Jennings, Julia Kenny, Stuart J. D. Neil, Michael H. Malim, Emma Timms, Jeffrey Seow, Sam Acors, Michael J. Carter
Publikováno v:
Nature Medicine
Recent reports highlight a new clinical syndrome in children related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)1—multisystem inflammatory syndrome in children (MIS-C)—which comprises multiorgan dysfunction and systemic inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9165713acef895b77605aca365527b
https://doi.org/10.1038/s41591-020-1054-6
https://doi.org/10.1038/s41591-020-1054-6