Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Paul Waterhouse"'
Autor:
Raid Amin, Alexis Angstadt, Vladimir Dragomirov, Maria Drury, Kyra Farinas, Michael Mezzano, Amy Muller, Paul Waterhouse
Publikováno v:
Statistics and Public Policy, Vol 11, Iss 1 (2024)
This study investigates the spatiotemporal variations in jail incarcerations in addition to associations with several risk factors and jail incarceration counts at the county level for the period 2010–2018 in the contiguous USA. The disease surveil
Externí odkaz:
https://doaj.org/article/1ce7a6927bc14f96a68f8bf847a929bb
Autor:
Thomas Kislinger, Ankit Sinha, Alison Aiken, Ashley Weiss, Hui Fang, Sanjay Saw, Sarah Bregant, Otto Sanchez, Vincent Dive, Brendan C. Dickson, Trevor D. McKee, Yan Chen, Rama Khokha, Amanda J. Fosang, Paul Waterhouse, Bertrand Czarny
Publikováno v:
The Journal of Cell Biology
Saw et al. show via the combinatorial deletion of Timp family members in mice that metalloprotease regulation of FGF-2 is a crucial event in the chondrocyte maturation program, underlying the growth plate development and bone elongation responsible f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7df9dd5924a1421b42c8599dfbcec9
https://doi.org/10.1083/jcb.201906059
https://doi.org/10.1083/jcb.201906059
Autor:
Katayoon Kasaian, Rama Khokha, Paul Waterhouse, Hui Fang, Hei Sook Sul, Olga Gulyaeva, Purna A. Joshi, Paul C. Boutros
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature communications, vol 10, iss 1
Nature communications, vol 10, iss 1
The mammary gland experiences substantial remodeling and regeneration during development and reproductive life, facilitated by stem cells and progenitors that act in concert with physiological stimuli. While studies have focused on deciphering regene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fed85e086c5e4ba4194b4cc0edd8ac0
http://link.springer.com/article/10.1038/s41467-019-09748-z
http://link.springer.com/article/10.1038/s41467-019-09748-z
Autor:
Miquel Angel Pujana, Michael J. Parsons, Hal K. Berman, Alison E. Casey, Luis Palomero, Kazeera Aliar, Thomas Kislinger, Swami R. Narala, Hyun-Chul Kim, Paul Waterhouse, Hofer S, Rama Khokha, Francesca Mateo, Mathepan Mahendralingam
It has long been assumed that all normal cells have the same capacity to engage homologous recombination (HR) and non-homologous end joining (NHEJ) to repair DNA double-strand breaks (DSBs), a concept exploited for DNA-damaging chemotherapeutics. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b8196882f05813d0581edeca35c6e37
https://doi.org/10.1101/2021.05.14.444217
https://doi.org/10.1101/2021.05.14.444217
Autor:
Sanjay Saw, Paul Waterhouse, Kazeera Aliar, Ronak Shetty, Hui Fang, Rama Khokha, Alison Aiken, Ashley Weiss, Yang W. Shao, Swami R. Narala
Publikováno v:
Blood advances. 5(20)
Bone marrow (BM) is the primary site of hematopoiesis and is responsible for a lifelong supply of all blood cell lineages. The process of hematopoiesis follows key intrinsic programs that also integrate instructive signals from the BM niche. First id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f08ee2ac7b67946fbeb125f3b8dc39
https://pubmed.ncbi.nlm.nih.gov/34500457
https://pubmed.ncbi.nlm.nih.gov/34500457
Autor:
Sam D. Molyneux, Hibret A. Adissu, Yang W. Shao, Qinglian Tang, Paul Waterhouse, Hui Fang, Jonathan Liu, Geoffrey A. Wood, Trevor D. McKee, Yan Chen, Rama Khokha, Jinchang Lu
Publikováno v:
Oncogene
Leveraging the conserved cancer genomes across mammals has the potential to transform driver gene discovery in orphan cancers. Here, we combine cross-species genomics with validation across human-dog-mouse systems to uncover a new bone tumor suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264aefab05693fb43ed856379753c7bc
https://doi.org/10.1038/s41388-018-0444-4
https://doi.org/10.1038/s41388-018-0444-4
Autor:
Dalia Barsyte-Lovejoy, Julie Livingstone, Ruth Isserlin, Geneviève Deblois, Hui Fang, Daniel D. De Carvalho, Tiago Medina, Thomas Kislinger, Paul C. Boutros, Pirashaanthy Tharmapalan, Alison E. Casey, Stefan Hofer, Swneke D. Bailey, Erik Drysdale, Hal K. Berman, Gary D. Bader, Mona Shehata, Rama Khokha, Mathieu Lupien, Yu-Jia Shiah, Rajat Singhania, Cheryl H. Arrowsmith, Stefan Knapp, Paul Waterhouse, Ankit Sinha, Hyeyeon Kim, Jennifer Cruickshank
Publikováno v:
The Journal of cell biology, vol 217, iss 8
The Journal of Cell Biology
The Journal of Cell Biology
Casey et al. integrate epigenomic, transcriptomic, and proteomic profiling of primary basal and luminal mammary cells to identify master epigenetic regulators of the mammary epithelium and uncover stem and progenitor cell vulnerabilities. They develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e98776b80141ee5fc4d896fb5e63c5
https://doi.org/10.1083/jcb.201804042
https://doi.org/10.1083/jcb.201804042
Autor:
Mathepan Mahendralingam, Marianne Koritzinsky, Paul Waterhouse, Rama Khokha, Ravi N. Vellanki, Mona Shehata, Hyeyeon Kim, Alison E. Casey
Publikováno v:
Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
The heterogeneity of breast cancer makes current therapies challenging. Metformin, the anti-diabetic drug, has shown promising anti-cancer activities in epidemiological studies and breast cancer models. Yet, how metformin alters the normal adult brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b0b87e400f02eb45bb2f3e6fb98762
http://europepmc.org/articles/PMC6527562
http://europepmc.org/articles/PMC6527562
Autor:
Robert E. Turcotte, Takeaki Ishii, Wajih Jawhar, Nada Jabado, Livia Garzia, Paul Waterhouse, Rama Khokha
Publikováno v:
Cancer Research. 80:A64-A64
Ewing sarcoma (ES) is a poorly differentiated bone and soft tissue tumor of high metastatic potential. ES mainly affects children, adolescents, and young adults (AYAs) at a frequency of ~1.5 cases per million globally. Ewing neoplasms strikingly conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92f4c34a3d2f4873454a421763f341de
https://doi.org/10.1158/1538-7445.pedca19-a64
https://doi.org/10.1158/1538-7445.pedca19-a64
Autor:
Isaac S. Harris, Dawne N. Shelton, Qinglian Tang, Tak W. Mak, Hal Berman, Christopher M Watling, Sam D. Molyneux, Zsuzsanna Izsvák, Pirashaanthy Tharmapalan, Geir Kjetil Sandve, Swneke D. Bailey, Brendan C. Dickson, Yang W. Shao, Mathieu Lupien, Paul Waterhouse, Jay S. Wunder, Xiaoyang Zhang, Rama Khokha
Publikováno v:
Nature Genetics. 52:464-464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8be1c9efce8169b9a918ea46f21a5661
https://doi.org/10.1038/s41588-020-0589-2
https://doi.org/10.1038/s41588-020-0589-2