Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Paul Waring"'
Autor:
Diar Aziz, Christine Lee, Venessa Chin, Kristine J Fernandez, Zoe Phan, kConFab Investigators, AOCS Study Group, Paul Waring, C Elizabeth Caldon
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 4, Pp 355-370 (2022)
Abstract Basal‐like breast cancer (BLBC) has a greater overlap in molecular features with high‐grade serous ovarian cancer (HGSOC) than with other breast cancer subtypes. Similarities include BRCA1 mutation, high frequency of TP53 mutation, and a
Externí odkaz:
https://doaj.org/article/a5b727e7474c49bbb67d277f89421abf
Autor:
Diar Aziz, Neil Portman, Kristine J. Fernandez, Christine Lee, Sarah Alexandrou, Alba Llop-Guevara, Zoe Phan, Aliza Yong, Ashleigh Wilkinson, C. Marcelo Sergio, Danielle Ferraro, Dariush Etemadmoghadam, David D. Bowtell, kConFab Investigators, Violeta Serra, Paul Waring, Elgene Lim, C. Elizabeth Caldon
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Basal-like breast cancers (BLBC) are aggressive breast cancers that respond poorly to targeted therapies and chemotherapies. In order to define therapeutically targetable subsets of BLBC we examined two markers: cyclin E1 and BRCA1 loss. In
Externí odkaz:
https://doaj.org/article/6daf1a428240435b83fc21ea45524a31
Autor:
Chun Gan, Clare Love, Victoria Beshay, Finlay Macrae, Stephen Fox, Paul Waring, Graham Taylor
Publikováno v:
Genes, Vol 6, Iss 1, Pp 46-59 (2015)
Microsatellite instability (MSI) is a useful marker for risk assessment, prediction of chemotherapy responsiveness and prognosis in patients with colorectal cancer. Here, we describe a next generation sequencing approach for MSI testing using the MiS
Externí odkaz:
https://doaj.org/article/31b1f99393254421be2a5147e227b8e4
Autor:
Richard D Telford, Ross B Cunningham, Paul Waring, Rohan M Telford, Lisa S Olive, Walter P Abhayaratna
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76124 (2013)
Background and objectivesElevated blood lipids during childhood are predictive of dyslipidemia in adults. Although obese and inactive children have elevated values, any potentially protective role of elementary school physical education is unknown. O
Externí odkaz:
https://doaj.org/article/aa6c792101334c1e90223859b01e022d
Autor:
Anjali Tikoo, Vincent Roh, Karen G Montgomery, Ivan Ivetac, Paul Waring, Rebecca Pelzer, Lauren Hare, Mark Shackleton, Patrick Humbert, Wayne A Phillips
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36924 (2012)
PIK3CA, the gene coding for the p110α subunit of phosphoinositide 3-kinase, is frequently mutated in a variety of human tumors including breast cancers. To better understand the role of mutant PIK3CA in the initiation and/or progression of breast ca
Externí odkaz:
https://doaj.org/article/79b86ce44cd14ab4b50082986f282edd
Autor:
Paul Waring, Martin Townsend
Third edition of the most comprehensive and authoritative guide to the larger moths of Great Britain and Ireland. This latest edition of the Field Guide to the Moths of Great Britain and Ireland has been fully revised, updated and restructured, bring
Autor:
Wayne A. Phillips, Owen J. Sansom, Patrick O. Humbert, Peter R. Shepherd, Toby J. Phesse, Kaylene J. Simpson, Matthew J. Smalley, Richard W. Clarkson, Carleen Cullinane, Luc Furic, Sarah Koushyar, Arthi A. Macpherson, Richard J. Rebello, Karen G. Montgomery, Paul Waring, Christina M. Fennell, Valerie S. Meniel, Jason Li, Helen B. Pearson
Supplementary Figure 7: Characterization of Pik3ca+/HR, Ptenfl/fl and Pik3ca+/HR;Ptenfl/fl prostate tumors. Representative images of IHC to detect (A) PCNA and (B) Cleaved-caspase 3 (CC3) in Pik3ca+/HR, Ptenfl/fl and Pik3ca+/HR;Ptenfl/fl prostate tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3488fe8b07def2dceebd43715c46b34f
https://doi.org/10.1158/2159-8290.22532960
https://doi.org/10.1158/2159-8290.22532960
Autor:
Guy Cavet, David Stokoe, John Chant, Levi A. Garraway, Paul Waring, Howard M. Stern, Somasekar Seshagiri, Zora Modrusan, Thinh Pham, William M. Lin, Steve Guerrero, Peng Yue, Sankar Mohan, Eva Lin, Ajay Pandita, Lin Ge, Barmak Modrek
Supplementary Data from Oncogenic Activating Mutations Are Associated with Local Copy Gain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2636ccc9d676c2228655d75c4591e990
https://doi.org/10.1158/1541-7786.22518897
https://doi.org/10.1158/1541-7786.22518897
Autor:
Wayne A. Phillips, Owen J. Sansom, Patrick O. Humbert, Peter R. Shepherd, Toby J. Phesse, Kaylene J. Simpson, Matthew J. Smalley, Richard W. Clarkson, Carleen Cullinane, Luc Furic, Sarah Koushyar, Arthi A. Macpherson, Richard J. Rebello, Karen G. Montgomery, Paul Waring, Christina M. Fennell, Valerie S. Meniel, Jason Li, Helen B. Pearson
Supplemetary Material and Tables S1 - S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578fd7c7f0304b17bda6ca3fb1f6dbfd
https://doi.org/10.1158/2159-8290.22532957
https://doi.org/10.1158/2159-8290.22532957
Autor:
Guy Cavet, David Stokoe, John Chant, Levi A. Garraway, Paul Waring, Howard M. Stern, Somasekar Seshagiri, Zora Modrusan, Thinh Pham, William M. Lin, Steve Guerrero, Peng Yue, Sankar Mohan, Eva Lin, Ajay Pandita, Lin Ge, Barmak Modrek
Although activating mutations and gains in copy number are key mechanisms for oncogene activation, the relationship between the two is not well understood. In this study, we focused on KRAS copy gains and mutations in non–small cell lung cancer. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083ea643665429b21da4bc48096c95c1
https://doi.org/10.1158/1541-7786.c.6542172
https://doi.org/10.1158/1541-7786.c.6542172