Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Paul W. Wedeking"'
1
A Noninvasive Method for Monitoring Renal Status at Bedside
Autor: H W Strauss, Paul W. Wedeking, Maria Fernandez, Michael F. Tweedle, Adrian D. Nunn, Xun Zhang
Publikováno v: INVESTIGATIVE RADIOLOGY. 32:802-805
RATIONALE AND OBJECTIVES The authors demonstrate the feasibility of monitoring renal status continuously and noninvasively at a patient's bedside, avoiding both radioactivity and blood and urine samples. METHODS Gadolinium-153-labeled ProHance and a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762ea265ed2bb92cc4f94e514f34213f
https://doi.org/10.1097/00004424-199712000-00011
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2
Pharmacokinetic analysis of blood distribution of intravenously administered 153Gd-labeled Gd(DTPA)2− and 99MTc(DTPA) in rats
Autor: D.G. Covell, S. Nair, Paul W. Wedeking, Stephen Eaton, Michael F. Tweedle, W.C. Eckelman
Publikováno v: Magnetic Resonance Imaging. 8:567-575
Rat plasma distribution data obtained following IV administration of 99mTc(DTPA) alone or after co-administration of 99mTc(DTPA) and 153Gd-labeled Gd(DTPA)2- at 0.001, 0.1, and 1.0 mmol Gd/kg were evaluated using compartmental modeling techniques. A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db932450c7c440c72240473755acea9c
https://doi.org/10.1016/0730-725x(90)90133-m
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4
Caenorhabditis elegans as an alternative animal species
Autor: Paul W. Wedeking, Michael F. Tweedle, Adrian D. Nunn, Phillip L. Williams, John L. Johnstone, Gary L. Anderson
Publikováno v: Journal of toxicology and environmental health. Part A. 61(8)
Caenorhabditis elegans has proven useful in toxicity testing of known toxicants, but its potential for assessing the toxicity of new pharmaceuticals is relatively unexplored. In this study the procedures used in aquatic testing of toxicants were modi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387d043f5270431fa7656e844eb5d4aa
https://pubmed.ncbi.nlm.nih.gov/11132694
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5
Biodistribution of radiolabeled, formulated gadopentetate, gadoteridol, gadoterate, and gadodiamide in mice and rats
Autor: Krishan Kumar, Paul W. Wedeking, Michael F. Tweedle
Publikováno v: Investigative radiology. 30(6)
The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in viv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322d7c103f40bff60f3fdfd1a3135b52
https://pubmed.ncbi.nlm.nih.gov/7490190
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7
Synthesis, Characterization, and Imaging Performance of a New Class of Macrocyclic Hepatobiliary MR Contrast Agents
Autor: Edmund R. Marinelli, Ramachandran S. Ranganathan, Kozikhott Sukumaran, Michael F. Tweedle, Bo Song, Adrian D. Nunn, Richard Neubeck, Paul W. Wedeking, Thomas Wagler, Val M. Runge
Publikováno v: Investigative Radiology. 35:8
To investigate the effect of substituent lipophilicity, substituent position, and overall charge on the hepatobiliary clearance and tolerance of a series of aromatic ring-containing macrocyclic Gd chelates to select a candidate compound for evaluatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a77f5ea3ab67f59b12f6410e4ca5e2
https://doi.org/10.1097/00004424-200001000-00002
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8
Comparison of chlordiazepoxide and food deprivation in rats on a fixed-ratio satiation schedule
Autor: Paul W. Wedeking
Publikováno v: Physiology & Behavior. 10:707-710
The effects and interactions of injected chlordiazepoxide HCl (CDP) and food deprivation in rats conditioned on a food-reinforced fixed ratio 10-satiation schedule were studied. Increasing the duration of food deprivation had no significant effect on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c419b66267428913eaa32308d86a7e6
https://doi.org/10.1016/0031-9384(73)90149-2
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9
A head-holder for inhalation anesthesia or resuscitation of rats
Autor: Paul W. Wedeking, R.G. Babington
Publikováno v: Pharmacology, biochemistry, and behavior. 2(1)
The design of a versatile rat head-holder is described. The head-holder enables the investigator to maintain close control close over the level of inhalation anesthesia; and, if desired, to resuscitate the animal.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db96ee0e0105ffced666aaf3606db9c
https://pubmed.ncbi.nlm.nih.gov/4828477
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10
Increase in tissue concentration of acetylcholine in guinea pigs in vivo induced by administration of choline
Autor: Paul W. Wedeking, Paulina F.L. Wang, Dean R. Haubrich
Publikováno v: Life sciences. 14(5)
Administration of choline chloride (200 μmoles/kg) intravenously to guinea pigs caused an increase in the concentrations of choline and acetylcholine in adrenals, heart, kidneys, lungs, and liver within 2 min. These results suggest that raising the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28e824ae09635a68317e527c669bd5d
https://pubmed.ncbi.nlm.nih.gov/4828407
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