Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Paul W. Wedeking"'
Autor:
H W Strauss, Paul W. Wedeking, Maria Fernandez, Michael F. Tweedle, Adrian D. Nunn, Xun Zhang
Publikováno v:
INVESTIGATIVE RADIOLOGY. 32:802-805
RATIONALE AND OBJECTIVES The authors demonstrate the feasibility of monitoring renal status continuously and noninvasively at a patient's bedside, avoiding both radioactivity and blood and urine samples. METHODS Gadolinium-153-labeled ProHance and a
Publikováno v:
Magnetic Resonance Imaging. 8:567-575
Rat plasma distribution data obtained following IV administration of 99mTc(DTPA) alone or after co-administration of 99mTc(DTPA) and 153Gd-labeled Gd(DTPA)2- at 0.001, 0.1, and 1.0 mmol Gd/kg were evaluated using compartmental modeling techniques. A
Autor:
Paul W. Wedeking, Krishan Kumar, Michael F. Tweedle, Adrian D. Nunn, Pillai Radhakrishna, Ramachandran S. Ranganathan, Edmund R. Marinelli
Publikováno v:
Academic Radiology. 3:S333-S335
Autor:
Paul W. Wedeking, Michael F. Tweedle, Adrian D. Nunn, Phillip L. Williams, John L. Johnstone, Gary L. Anderson
Publikováno v:
Journal of toxicology and environmental health. Part A. 61(8)
Caenorhabditis elegans has proven useful in toxicity testing of known toxicants, but its potential for assessing the toxicity of new pharmaceuticals is relatively unexplored. In this study the procedures used in aquatic testing of toxicants were modi
Publikováno v:
Investigative radiology. 30(6)
The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in viv
Autor:
Michael F. Tweedle, Richard Neubeck, Edmund R. Marinelli, Radhakrishna Pillai, J. Emswiler, R. S. Ranganathan, Thangavel Arunachalam, L. Duncan, Paul W. Wedeking, Diamantidis G
Publikováno v:
Investigative radiology. 26
Autor:
Edmund R. Marinelli, Ramachandran S. Ranganathan, Kozikhott Sukumaran, Michael F. Tweedle, Bo Song, Adrian D. Nunn, Richard Neubeck, Paul W. Wedeking, Thomas Wagler, Val M. Runge
Publikováno v:
Investigative Radiology. 35:8
To investigate the effect of substituent lipophilicity, substituent position, and overall charge on the hepatobiliary clearance and tolerance of a series of aromatic ring-containing macrocyclic Gd chelates to select a candidate compound for evaluatio
Autor:
Paul W. Wedeking
Publikováno v:
Physiology & Behavior. 10:707-710
The effects and interactions of injected chlordiazepoxide HCl (CDP) and food deprivation in rats conditioned on a food-reinforced fixed ratio 10-satiation schedule were studied. Increasing the duration of food deprivation had no significant effect on
Autor:
Paul W. Wedeking, R.G. Babington
Publikováno v:
Pharmacology, biochemistry, and behavior. 2(1)
The design of a versatile rat head-holder is described. The head-holder enables the investigator to maintain close control close over the level of inhalation anesthesia; and, if desired, to resuscitate the animal.
Publikováno v:
Life sciences. 14(5)
Administration of choline chloride (200 μmoles/kg) intravenously to guinea pigs caused an increase in the concentrations of choline and acetylcholine in adrenals, heart, kidneys, lungs, and liver within 2 min. These results suggest that raising the