Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paul W. Mellick"'
Autor:
Paul C. Howard, Paul W. Mellick, Robert P. Felton, Peter P. Fu, Mary D. Boudreau, Frederick A. Beland, Brett T. Thorn, Greg R. Olson
Publikováno v:
Photochemistry and photobiology. 93(4)
Cosmetic products that contain retinyl palmitate are popular as antiaging skin treatments; however, recent studies suggest a risk for enhanced skin tumor development with topical retinyl palmitate applications and exposure to solar ultraviolet radiat
Autor:
Joseph E. Tomaszewski, Carlo Contoreggi, Patrick T. Curry, Elizabeth R. Glaze, David L. McCormick, J. Brooks Harder, Robert L. Morrissey, Kenner C. Rice, Dennis S. Charney, Giovanni Cizza, Karim A. Calis, Thomas L. Horn, Ralph E. Parchment, Philip W. Gold, Paul W. Mellick, William D. Johnson
Publikováno v:
Toxicology. 248:8-17
Non-clinical studies were conducted to evaluate the toxicity of Antalarmin, a corticotropin-releasing hormone type 1 receptor antagonist being developed for therapy of stress-related pathologies. Antalarmin was not genotoxic in bacterial mutagenesis
Autor:
Sandra J. Culp, Kevin J. Greenlees, Ralph L. Kodell, Ronald W. Trotter, Frederick A. Beland, Paul W. Mellick
Publikováno v:
Food and Chemical Toxicology. 44:1204-1212
Malachite green is a triphenylmethane dye used in the fish industry as an anti-fungal agent. Leucomalachite green is formed by the metabolic reduction of malachite green and persists in the tissues of exposed fish. In this study, we examined the carc
Carcinogenicity of acrylamide in B6C3F(1) mice and F344/N rats from a 2-year drinking water exposure
Autor:
Frederick A. Beland, Paul W. Mellick, Greg R. Olson, Maria C.B. Mendoza, M. Matilde Marques, Daniel R. Doerge
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 51
Acrylamide is a component of roasted coffee and certain baked and fried carbohydrate-rich foods prepared at high temperatures. We have assessed the carcinogenicity of acrylamide in male and female B6C3F(1) mice and F344/N rats administered 0, 0.0875,
Autor:
Tracie L. Verkler, Robert R. Delongchamp, Letha H. Couch, Paul C. Howard, Paul W. Mellick, Barbara J. Miller, Alan Warbritton, Barbara L. Parsons
Publikováno v:
Molecular carcinogenesis. 47(11)
The p53 codon 270 CGT to TGT mutation was investigated as a biomarker of sunlight-induced mutagenesis and carcinogenesis. The relationship between tumor development and abundance of this hotspot mutation was analyzed in mouse skin tumors induced by c
Autor:
Jia-Long Fang, R. Wayne Benson, Robert M. Kovatch, Frederick A. Beland, Paul W. Mellick, Dean W. Roberts, Daniel R. Doerge
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 43(1)
Urethane is a carcinogen to which there is widespread exposure through the consumption of fermented foods and alcoholic beverages. In this study, we have assessed the carcinogenicity of urethane in combination with ethanol. Male and female B6C3F(1) m
Publikováno v:
Cell Calcium. 1:69-79
1,25(OH)2D3 increases cell permeability to calcium. This increase is not mediated by proteins sensitive to cycloheximide or actinomycin D inhibition. We propose that CaBP may associate with intracellular membranes and organelles to prevent intracellu
Publikováno v:
The Journal of surgical research. 28(3)
The growth of small bowel mucosa onto enteric segments, denuded of mucosa, and onto prosthetic material was studied under light and electron microscopy. Mongrel dogs were divided into seven experimental groups. In Group I, 10-cm-long mucosally denude
Publikováno v:
Journal of medical virology. 24(2)
Nineteen street rabies virus strains, isolated in Egypt from humans (two), dogs (nine), cats (two), farm animals (two), gerbils (three), and a jackal were antigenically analyzed. The Pasteur strain used for the preparation of human rabies vaccine, th