Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Paul W. Kletzly"'
Autor:
Vincent J. Kalish, Tays Kevin L, Larisa Serdyuk, Ge Xiao, Jie Zhang, Dana Ferraris, Susan Lautar, Weixing Li, Jia-He Li, Paul W. Kletzly
Publikováno v:
ChemInform. 32
1-, 2-, 3-, 4-, 8-, or 10-Substituted 5(H)phenanthridin-6-ones were synthesized and found to be potent PARP1 inhibitors. Among the 28 compounds prepared, some showed not only low IC50 values (compound 1b, 10 nM) but also desirable water solubility ch