Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Paul W. Hollenbach"'
Autor:
Paul W Hollenbach, Aaron N Nguyen, Helen Brady, Michelle Williams, Yuhong Ning, Normand Richard, Leslie Krushel, Sharon L Aukerman, Carla Heise, Kyle J MacBeth
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9001 (2010)
BACKGROUND: The cytidine nucleoside analogs azacitidine (AZA) and decitabine (DAC) are used for the treatment of patients with myelodysplastic syndromes and acute myeloid leukemia (AML). Few non-clinical studies have directly compared the mechanisms
Externí odkaz:
https://doaj.org/article/80331f59b43f47a1b73c70859de811dc
Autor:
Hon-Wah Man, Namrata D. Udeshi, D. R. Mani, Marie McConkey, Anita Gandhi, Lars Bullinger, Emma C. Fink, Steven A. Carr, Slater N. Hurst, Brian E. Cathers, Elizabeth A. Griffiths, Tanya Svinkina, Rebekka K. Schneider, Meir Wetzler, Jan Krönke, Rajesh Chopra, Marcus Järås, Philip P Chamberlain, Kyle J. MacBeth, Benjamin L. Ebert, Paul W. Hollenbach
Publikováno v:
Nature. 523(7559)
Lenalidomide is a highly effective treatment for myelodysplastic syndrome (MDS) with deletion of chromosome 5q (del(5q)). Here, we demonstrate that lenalidomide induces the ubiquitination of casein kinase 1A1 (CK1α) by the E3 ubiquitin ligase CUL4-R
Autor:
Aaron N. Nguyen, Kyle J. MacBeth, Carla Heise, Normand Richard, Paul W. Hollenbach, Antonio Luna-Moran, Helen Brady
Publikováno v:
Lung Cancer: Targets and Therapy.
Aaron N Nguyen1, Paul W Hollenbach1, Normand Richard2, Antonio Luna-Moran1, Helen Brady2, Carla Heise1, Kyle J MacBeth11Celgene Corporation, San Francisco, CA, USA; 2Celgene Corporation, San Diego, CA, USAAbstract: Azacitidine (AZA) and decitabine (D
Autor:
Yuhong Ning, Helen Brady, Carla Heise, Sharon L. Aukerman, Kyle J. MacBeth, Normand Richard, Paul W. Hollenbach, Leslie A. Krushel, Aaron N. Nguyen, Michelle A. Williams
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 2, p e9001 (2010)
PLoS ONE, Vol 5, Iss 2, p e9001 (2010)
BACKGROUND: The cytidine nucleoside analogs azacitidine (AZA) and decitabine (DAC) are used for the treatment of patients with myelodysplastic syndromes and acute myeloid leukemia (AML). Few non-clinical studies have directly compared the mechanisms
Publikováno v:
Journal of Biological Chemistry. 267:39-42
In this report we have examined the ability of tumor necrosis factor-alpha (TNF) to induce the activity of phospholipase A2 (PLA2) in the cell line C3HA, a murine 3T3-like cell line which is normally resistant to TNF-induced cytolysis but can be sens
Autor:
Paul W. Hollenbach
Publikováno v:
The Anchor Yale Bible Dictionary. :887-899
Publikováno v:
Blood. 124:3606-3606
Background: Lenalidomide has broad clinical activity in hematologic malignancies, including lymphoid malignancies (multiple myeloma (MM), non-Hodgkin’s lymphomas, B cell chronic lymphocytic leukemia) and myeloid malignancies (myelodysplastic syndro
Autor:
Eric A. Gulve, Ying Yu, Brian R. Bond, Ronald J. Hill, Amy E. Halseth, Stuart A. Ross, Paul W. Hollenbach
Publikováno v:
Biochemical and biophysical research communications. 334(4)
Non-receptor proline-rich tyrosine kinase-2 (PYK2), which is activated by phosphorylation of one or more of its tyrosine residues, has been implicated in the regulation of GLUT4 glucose transporter translocation and glucose transport. Some data favor
Autor:
Gregory N. Weddell, Barbara E. Pearson, Carole G. Kurahara, Clive S. Woodhouse, Roanna M. Ueda, Paul W. Hollenbach, Robert M. Kay, Ted K. Choi, Jeanne F. Loring
Publikováno v:
Nature genetics. 4(2)
We have developed a method for the introduction of yeast artificial chromosomes (YACs) into transgenic mice. An 85 kilobase (kb) fragment of the human heavy chain immunoglobulin gene was cloned as a YAC, and embryonic stem cell lines carrying intact,
Autor:
Carole G. Kurahara, Roanna M. Ueda, Jeanne F. Loring, Barbara E. Pearson, Ted K. Choi, Clive S. Woodhouse, Gregory N. Weddell, Paul W. Hollenbach, Robert M. Kay
Publikováno v:
Nature Genetics. 4:320-320