Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Paul W. Brown"'
Publikováno v:
Journal of Chromatography A. 1586:72-81
Polysorbates are complex mixtures of over a thousand components with a wide range of hydrophobicity. This paper describes a methodology for characterization of heterogeneity and stability of polysorbates in therapeutic protein formulation. The method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9ab2ba765fd0e3d40ee899bbad71ea
https://doi.org/10.1016/j.chroma.2018.11.080
https://doi.org/10.1016/j.chroma.2018.11.080
Autor:
Jin Xie, Olga V. Friese, Michael T. Jones, Wei Huang, Hanliu Leah Wang, Keith A. Davis, Mingzhang Wang, Jason C. Rouse, Stephen A. Kolodziej, James A. Carroll, Paul W. Brown, Qin Zou
Publikováno v:
Carbohydrate research. 495
Bacterial capsular polysaccharide protein conjugates are a major class of vaccines for preventing severe bacterial infections. The conjugation of a polysaccharide to a carrier protein is critical for inducing adaptive immune response in healthy human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ad620bdf2a441e0523804121ba4084
https://pubmed.ncbi.nlm.nih.gov/32807353
https://pubmed.ncbi.nlm.nih.gov/32807353
Autor:
Karin Anderson, Robert L. Dufield, Jason C. Rouse, Olga V. Friese, Chia H. Chu, James A. Carroll, Bruno Figueroa, Paul W. Brown, Heather S. DeGruttola, Wenge Wang, T. Jennifer Lin, Gerald Fries Casperson, Kathryn M. Beal, Mellisa Ly, Lisa A. Marzilli
Publikováno v:
mAbs
Amino acid sequence variation in protein therapeutics requires close monitoring during cell line and cell culture process development. A cross-functional team of Pfizer colleagues from the Analytical and Bioprocess Development departments worked clos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75836bdc18f8bf5c957e82f380afacaf
https://doi.org/10.1080/19420862.2018.1531965
https://doi.org/10.1080/19420862.2018.1531965
Publikováno v:
mAbs. 10(3)
Antibody-drug conjugation strategies are continuously evolving as researchers work to improve the safety and efficacy of the molecules. However, as a part of process and product development, confirmation of the resulting innovative structures require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b1faf833aaee350afbeca3a8cddda0
https://pubmed.ncbi.nlm.nih.gov/29393747
https://pubmed.ncbi.nlm.nih.gov/29393747
Autor:
Paul W. Brown, Brent Constantz
Biological and Synthetic Apatites (R.Z. LeGeros). Calcium Phosphate Apatites in Nature (D.K. Smith). Hydrothermal Processing of Hydroxyapatite: Past, Present, and Future (M. Yoshimura and H. Suda). Formation and Dissolution Mechanisms of Calcium Phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b46d1fdba4bade2ef696fba14e7e23ec
https://doi.org/10.1201/9780203751367
https://doi.org/10.1201/9780203751367
Publikováno v:
Land Use Policy. 45:76-85
Agricultural policy objectives in developed nations include counteracting overproduction, increasing economic and social well-being, and environmental protection. Such policies, however, often work at cross-purposes. While vast financial resources ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::183dd92b15f33ad07917548b69f065ca
https://doi.org/10.1016/j.landusepol.2015.01.002
https://doi.org/10.1016/j.landusepol.2015.01.002
Autor:
Brad Evans, Keith A. Davis, Joe T. Collins, Keshab Bhattacharya, Anouk Dirksen, Jari I. Finneman, Paul W. Brown, Erin Pepin, Jeffrey S. Ryczek, Ratish Mangalathillam, William B. Wellborn, Mark John Pozzo, Rory F. Finn
Publikováno v:
Biopolymers.
A scalable, viable process was developed for the Fibroblast Growth Factor 21 (FGF21) protein-antibody conjugate, CVX-343, an extended half-life therapeutic for the treatment of metabolic disease. CVX-343 utilizes the CovX antibody scaffold technology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88789a43a56b3aaa1e140488c09b7a9f
https://pubmed.ncbi.nlm.nih.gov/28948603
https://pubmed.ncbi.nlm.nih.gov/28948603
Publikováno v:
Journal of Soil and Water Conservation. 68:67A-73A
W hile Americans are accustomed to US Congress revisiting the farm bill every five to seven years, less familiar is the breadth of influence agricultural policy has in today's society. For example, as 2012 waned without a new farm bill, surprised con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c22e58652cd9e7f6fce115703b208b
https://doi.org/10.2489/jswc.68.3.67a
https://doi.org/10.2489/jswc.68.3.67a
Autor:
Lakshmi S. Nair, Yaser E. Greish, Paul W. Brown, Harry R. Allcock, Anurima Singh, J. D. Bender, Cato T. Laurencin
Publikováno v:
Ceramics International. 39:519-528
Hard tissues are made of nanoapatite crystallites grown on a nanofibrous collagen matrix. The mechanical interlocking and the chemical bonding between both phases provide the unique properties of hard tissues. A biodegradable alanine-substituted poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8dfd72ec77d245a631afa1ae6f0bcb
https://doi.org/10.1016/j.ceramint.2012.06.057
https://doi.org/10.1016/j.ceramint.2012.06.057
Autor:
John E. Schiel, Darryl L. Davis, Oleg V. Borisov, Trina Formolo, Mellisa Ly, Michaella Levy, Lisa Kilpatrick, Scott Lute, Karen Phinney, Lisa Marzilli, Kurt Brorson, Michael Boyne, Darryl Davis, John Schiel, Melissa Alvarez, James A. Carroll, Paul W. Brown, Wenzhou Li, James L. Kerwin, Andrew Mahan, Sabrina A. Benchaar, Justin M. Prien, Henning Stöckmann, Simone Albrecht, Silvia M. Martin, Matthew Varatta, Marsha Furtado, Stephen Hosselet, Meiyao Wang, Pauline M. Rudd, David A. Michels, Anna Y. Ip, Thomas M. Dillon, Brittany Chavez, Ken M. Prentice, Lowell J. Brady, Karen J. Miller, Yatin Gokarn, Sanjeev Agarwal, Kelly Arthur, Alexander Bepperling, Eric S. Day, Dana Filoti, Daniel G. Greene, David Hayes, Rachel Kroe-Barrett, Thomas Laue, Jasper Lin, Brian McGarry, Vladimir Razinkov, Sanjaya Singh, Rosalynn Taing, Sathyadevi Venkataramani, William Weiss, Danlin Yang, Isidro E. Zarraga, Dorina Saro, Audrey Baker, Robert Hepler, Stacey Spencer, Rick Bruce, Steven LaBrenz, Mark Chiu, Steven E. Lang, Dean C. Ripple, Linda O. Narhi, Kesh Prakash, Weibin Che