Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Paul W Wright"'
Autor:
Hongchuan Li, Martin A Ivarsson, Victoria E Walker-Sperling, Jeff Subleski, Jenna K Johnson, Paul W Wright, Mary Carrington, Niklas K Björkström, Daniel W McVicar, Stephen K Anderson
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007163 (2018)
The HLA-C gene appears to have evolved in higher primates to serve as a dominant source of ligands for the KIR2D family of inhibitory MHC class I receptors. The expression of NK cell-intrinsic MHC class I has been shown to regulate the murine Ly49 fa
Externí odkaz:
https://doaj.org/article/14bc14013bbd454a96b9e42facee3ca7
Autor:
Hongchuan Li, Md Ahasanur Rahman, Michael Ruesch, Caprice D. Eisele, Erik M. Anderson, Paul W. Wright, Jennie Cao, Shashikala Ratnayake, Qingrong Chen, Chunhua Yan, Daoud Meerzaman, Roshini S. Abraham, Aharon G. Freud, Stephen K. Anderson
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113454- (2023)
Summary: Previous studies of the murine Ly49 and human KIR gene clusters implicated competing sense and antisense promoters in the control of variegated gene expression. In the current study, an examination of transcription factor genes defines an ab
Externí odkaz:
https://doaj.org/article/53ef519c8e7344d8ac994b0e279e76e5
Autor:
Frederick J. Goodson-Gregg, Brian Rothbard, Amy Zhang, Paul W. Wright, Hongchuan Li, Victoria E. Walker-Sperling, Mary Carrington, Stephen K. Anderson
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
A complex system regulating HLA-C expression in NK cells, driven by an NK-specific promoter that produces alternatively spliced variants of the 5′-UTR has been recently identified. Exon content of the NK-specific 5′-UTR varies strikingly across H
Externí odkaz:
https://doaj.org/article/c925690f8eae457d8eb7c8f9a6010fae
Autor:
Hongchuan Li, Md Ahasanur Rahman, Paul W Wright, Jennie Cao, Shashikala Ratnayake, Qingrong Chen, Chunhua Yan, Daoud Meerzaman, Aharon G Freud, Stephen K Anderson
Previous studies of the murine Ly49 and human KIR gene clusters have revealed a role for bidirectional promoters in the control of variegated gene expression. Whether or not competing promoters control other instances of cell fate determination remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::342300b0325473d589de47958eaa0b5e
https://doi.org/10.1101/2022.06.22.497234
https://doi.org/10.1101/2022.06.22.497234
Autor:
Holliday T. Carper, Lyndsey M. Muehling, Brian J. Capaldo, William W. Kwok, Judith A. Woodfolk, Deborah D. Murphy, Lisa J. Workman, Ronald B. Turner, Rachana Agrawal, Sarah J. Ratcliffe, Thomas Ae Platts-Mills, Jacob D. Eccles, Peter W. Heymann, Paul W. Wright, Carolyn R. Word
Publikováno v:
J Allergy Clin Immunol
Background Allergic asthmatic subjects are uniquely susceptible to acute wheezing episodes provoked by rhinovirus. However, the underlying immune mechanisms and interaction between rhinovirus and allergy remain enigmatic, and current paradigms are co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a3b72d02a679571818a412b35aed92
https://pubmed.ncbi.nlm.nih.gov/32673613
https://pubmed.ncbi.nlm.nih.gov/32673613
Autor:
Sampo J. Lahtinen, Paul W. Wright, Markus J. Lehtinen, Ronald B. Turner, John W. Steinke, Spencer C. Payne, Lyndsey M. Muehling, Peter W. Heymann, Larry Borish, Nicole A. Kirk, Deborah Thacker, Judith A. Woodfolk, Jacob D. Eccles
Publikováno v:
Cell reports
Cell Reports, Vol 30, Iss 2, Pp 351-366.e7 (2020)
Cell Reports, Vol 30, Iss 2, Pp 351-366.e7 (2020)
SUMMARY Human rhinoviruses cause the common cold and exacerbate chronic respiratory diseases. Although infection elicits neutralizing antibodies, these do not persist or cross-protect across multiple rhinovirus strains. To analyze rhinovirus-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be590f626e8077c024b76536166c9027
http://europepmc.org/articles/PMC6994188
http://europepmc.org/articles/PMC6994188
There are several aspects of HLA-C gene expression that distinguish it from the HLA-A and HLA-B genes. First, HLA-C is expressed by extravillous trophoblasts, whereas HLA-A and HLA-B are not. Second, its cell-surface expression is much lower, which h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abf33781bd99e140f40f146df7b3e23
https://europepmc.org/articles/PMC6251741/
https://europepmc.org/articles/PMC6251741/
Publikováno v:
Genes and immunity
The human killer cell immunoglobulin-like receptor (KIR) genes contain multiple promoters that control the process of gene activation and variegated expression of KIR on natural killer (NK) and T cells. Specific subfamilies of KIR genes have differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c67f4c64259ae9b43908ab4b8b4375a
https://doi.org/10.1038/gene.2015.56
https://doi.org/10.1038/gene.2015.56
Autor:
Jenna K. Johnson, Martin A. Ivarsson, Victoria Walker-Sperling, Stephen K. Anderson, Mary Carrington, Daniel W. McVicar, Jeff Subleski, Niklas K. Björkström, Paul W. Wright, Hongchuan Li
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 1, p e1007163 (2018)
PLoS Genetics, Vol 14, Iss 1, p e1007163 (2018)
The HLA-C gene appears to have evolved in higher primates to serve as a dominant source of ligands for the KIR2D family of inhibitory MHC class I receptors. The expression of NK cell-intrinsic MHC class I has been shown to regulate the murine Ly49 fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f6308837d5a008c39b20ce152c0743
https://pubmed.ncbi.nlm.nih.gov/29329284
https://pubmed.ncbi.nlm.nih.gov/29329284
Autor:
Sampo J. Lahtinen, William W. Kwok, James T. Patrie, Lyndsey M. Muehling, Judith A. Woodfolk, Paul W. Wright, Ronald B. Turner, Markus J. Lehtinen, Kenneth B. Brown
Publikováno v:
The Journal of infectious diseases. 217(3)
Background Little is known about T cells that respond to human rhinovirus in vivo, due to timing of infection, viral diversity, and complex T-cell specificities. We tracked circulating CD4+ T cells with identical epitope specificities that responded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b22f33fa9683191363fcc553c8d14d
https://pubmed.ncbi.nlm.nih.gov/29309618
https://pubmed.ncbi.nlm.nih.gov/29309618