Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Paul W Wiseman"'
Autor:
Yong Qian, Danielle M Orozco Cosio, Kiryl D Piatkevich, Sarah Aufmkolk, Wan-Chi Su, Orhan T Celiker, Anne Schohl, Mitchell H Murdock, Abhi Aggarwal, Yu-Fen Chang, Paul W Wiseman, Edward S Ruthazer, Edward S Boyden, Robert E Campbell
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000965 (2020)
Near-infrared (NIR) genetically encoded calcium ion (Ca2+) indicators (GECIs) can provide advantages over visible wavelength fluorescent GECIs in terms of reduced phototoxicity, minimal spectral cross talk with visible light excitable optogenetic too
Externí odkaz:
https://doaj.org/article/c61b9ef989474c1c9da003b377045026
Autor:
Tim Toplak, Benoit Palmieri, Alba Juanes-García, Miguel Vicente-Manzanares, Martin Grant, Paul W Wiseman
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186058 (2017)
We introduce and use Wavelet Imaging on Multiple Scales (WIMS) as an improvement to fluorescence correlation spectroscopy to measure physical processes and features that occur across multiple length scales. In this study, wavelet transforms of cell i
Externí odkaz:
https://doaj.org/article/57d0082bc7a44883881d6e7f3f3168d2
Autor:
Loïs S Miraucourt, Jennifer Tsui, Delphine Gobert, Jean-François Desjardins, Anne Schohl, Mari Sild, Perry Spratt, Annie Castonguay, Yves De Koninck, Nicholas Marsh-Armstrong, Paul W Wiseman, Edward S Ruthazer
Publikováno v:
eLife, Vol 5 (2016)
Type 1 cannabinoid receptors (CB1Rs) are widely expressed in the vertebrate retina, but the role of endocannabinoids in vision is not fully understood. Here, we identified a novel mechanism underlying a CB1R-mediated increase in retinal ganglion cell
Externí odkaz:
https://doaj.org/article/c2fa602935ed4280aa687251b41efb0a
Autor:
Hélène Klein, Asmahan Abu-Arish, Nguyen Thu Ngan Trinh, Yishan Luo, Paul W Wiseman, John W Hanrahan, Emmanuelle Brochiero, Rémy Sauvé
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153665 (2016)
In epithelia, Cl- channels play a prominent role in fluid and electrolyte transport. Of particular importance is the cAMP-dependent cystic fibrosis transmembrane conductance regulator Cl- channel (CFTR) with mutations of the CFTR encoding gene causin
Externí odkaz:
https://doaj.org/article/b2d22ba4692140e39bcc97e4bbc5e6f2
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159405 (2016)
Netrin-1 is an essential extracellular chemoattractant that signals through its receptor DCC to guide commissural axon extension in the embryonic spinal cord. DCC directs the organization of F-actin in growth cones by activating an intracellular prot
Externí odkaz:
https://doaj.org/article/8cd2c884206b4faa8229be03347f71d4
Autor:
Eva C Arnspang, Jeremy Schwartzentruber, Mathias P Clausen, Paul W Wiseman, B Christoffer Lagerholm
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e78096 (2013)
The lateral dynamics of proteins and lipids in the mammalian plasma membrane are heterogeneous likely reflecting both a complex molecular organization and interactions with other macromolecules that reside outside the plane of the membrane. Several m
Externí odkaz:
https://doaj.org/article/5f8b1d0ab520404fa3d54bca2fd98570
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36215 (2012)
Membrane transporter proteins exist in a complex dynamic equilibrium between various oligomeric states that include monomers, dimers, dimer of dimers and higher order oligomers. Given their sub-optical microscopic resolution size, the oligomerization
Externí odkaz:
https://doaj.org/article/9b1161ce2b9c4ddabe2783eed8b5e5d8
Autor:
Lingfeng Chen, Miguel Vicente-Manzanares, Laurent Potvin-Trottier, Paul W Wiseman, Alan Rick Horwitz
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40202 (2012)
Adhesive and migratory behavior can be cell type, integrin, and substrate dependent. We have compared integrin and substrate differences using three integrin receptors: α5β1, α6β1, and αLβ2 expressed in a common cell type, CHO.B2 cells, which l
Externí odkaz:
https://doaj.org/article/4b940897e3bf4c5b8188878d4b0d81c0
Publikováno v:
New Journal of Physics, Vol 15, Iss 8, p 085006 (2013)
We introduce a new generalized theoretical framework for image correlation spectroscopy (ICS). Using this framework, we extend the ICS method in time–frequency ( ν , nu) space to map molecular flow of fluorescently tagged proteins in individual li
Externí odkaz:
https://doaj.org/article/1db68b2829b94937bddb0d851b70ecfe
Autor:
Ze Gong, Koen van den Dries, Rodrigo A. Migueles-Ramírez, Paul W. Wiseman, Alessandra Cambi, Vivek B. Shenoy
Publikováno v:
Nature Communications, 14
Nature Communications, 14, 1
Nature Communications, 14, 1
Contains fulltext : 293171.pdf (Publisher’s version ) (Open Access) Immune cells, such as macrophages and dendritic cells, can utilize podosomes, mechanosensitive actin-rich protrusions, to generate forces, migrate, and patrol for foreign antigens.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28665fcd12958617d01012a9f427a434
http://hdl.handle.net/2066/293171
http://hdl.handle.net/2066/293171
