Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Paul W Naumann"'
Autor:
Sara M Reed, Jussara Hagen, Viviane P Muniz, Timothy R Rosean, Nick Borcherding, Sebastian Sciegienka, J Adam Goeken, Paul W Naumann, Weizhou Zhang, Van S Tompkins, Siegfried Janz, David K Meyerholz, Dawn E Quelle
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112126 (2014)
Nuclear Interactor of ARF and Mdm2 (NIAM, gene designation Tbrg1) is a largely unstudied inhibitor of cell proliferation that helps maintain chromosomal stability. It is a novel activator of the ARF-Mdm2-Tip60-p53 tumor suppressor pathway as well as
Externí odkaz:
https://doaj.org/article/9c544ff0f4564561a32fe2479115b285
Autor:
Paul W. Naumann, Christine L. Wohlford-Lenane, Nita H. Salzman, Paul B. McCray, David K. Meyerholz, Jennifer A. Bartlett
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 5, Pp 501-508 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms
Otitis media (inflammation of the middle ear) is one of the most common diseases of early childhood. Susceptibility to otitis is influenced by a number of factors, including the actions of innate immune molecules secreted by the epithelia lining the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2342dedd6ef61bb176c7004b2134a590
https://doi.org/10.1242/dmm.019646
https://doi.org/10.1242/dmm.019646
Autor:
Christopher S. Rogers, Paul W. Naumann, Emily Hammond, Xiao-Jun Wang, Jussara Hagen, J. Adam Goeken, David K. Meyerholz, Richard Van Rheeden, Agshin F. Taghiyev, Frank Rohret, Mariah R. Leidinger, John D. Newell, Jason T. Struzynski, Bryan T. Davis, Judy A. Rohret, Dawn E. Quelle, Benjamin W. Darbro, Jessica C. Sieren
Publikováno v:
Journal of Clinical Investigation. 124:4052-4066
Cancer is the second deadliest disease in the United States, necessitating improvements in tumor diagnosis and treatment. Current model systems of cancer are informative, but translating promising imaging approaches and therapies to clinical practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde9a35375c8842dbd67f21649660459
https://doi.org/10.1172/jci75447
https://doi.org/10.1172/jci75447
Autor:
J. Adam Goeken, Allyn M. Lambertz, Paul W. Naumann, Nitin J. Karandikar, Mariah R. Leidinger, Katherine N. Gibson-Corley, Georgina K. Ofori-Amanfo, Alexander W. Boyden
Publikováno v:
PeerJ
PeerJ, Vol 4, p e1600 (2016)
PeerJ, Vol 4, p e1600 (2016)
Experimental autoimmune encephalomyelitis (EAE) is a well-established mouse model for multiple sclerosis and is characterized by infiltration of mononuclear cells and demyelination within the central nervous system along with the clinical symptoms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73462c9e352817ecb8bcb41f8fbf1414
http://europepmc.org/articles/PMC4741089
http://europepmc.org/articles/PMC4741089
Autor:
Jon C. D. Houtman, Colleen Fullenkamp, Paul W. Naumann, Jonathan W. Heusel, Catherine A. Forbes, Anthony A. Scalzo, Natalya V. Guseva, Zuhair K. Ballas, Michael R. Shey
Publikováno v:
European Journal of Immunology. 40:2618-2631
Natural killer (NK) cell-mediated resistance to murine cytomegalovirus (MCMV) is controlled by allelic Ly49 receptors, including activating Ly49H (C57BL/6 strain) and inhibitory Ly49I (129 strain), which specifically recognize MCMV m157, a glycosylph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981d3f4299bfff13df3d93f6ce5ffd44
https://doi.org/10.1002/eji.200940134
https://doi.org/10.1002/eji.200940134
Publikováno v:
Pathobiology. 63:65-70
We tested non-hematopoietic human tumors for in vitro sensitivity to either a pair of synergistic IgG antitransferrin (Tf) receptor monoclonal antibodies (MAbs), deferoxamine (DFO) or the combination thereof. With an equimolar mixture of the two MAbs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c875b79bdf4858a02215147db995b60a
https://doi.org/10.1159/000163935
https://doi.org/10.1159/000163935
Autor:
Mary Sturm, David K. Meyerholz, Alicia K. Olivier, Katherine N. Gibson-Corley, Paul W. Naumann, Christine Hochstedler, Janis R Rodgers, Adam Goeken
Publikováno v:
Journal of histotechnology. 35(2)
Translational research using animal models has traditionally involved genetically modified rodents; however, there is increasing use of other novel genetically engineered species. As histology laboratories interface with researchers studying these no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b85a3506b742af5080a4cc3813af9f
https://pubmed.ncbi.nlm.nih.gov/22904582
https://pubmed.ncbi.nlm.nih.gov/22904582
Autor:
Hongshu Sui, Jeffrey J. Wine, Paul W. Naumann, Weihong Zhou, Xingshen Sun, Yaling Yi, Timothy S. Frana, Xiaoming Liu, Michelle Griffin, Yulong Zhang, Joann M. Kinyon, Ziying Yan, Diana C.M. Lei-Butters, Hyung Ju Cho, Nam Soo Joo, John T. Fisher, John F. Engelhardt, Kai Wang, David K. Meyerholz, Jill Ascher, Meihui Luo
Publikováno v:
The Journal of clinical investigation. 120(9)
Cystic fibrosis (CF) is a recessive disease that affects multiple organs. It is caused by mutations in CFTR. Animal modeling of this disease has been challenging, with species- and strain-specific differences in organ biology and CFTR function influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2238d4efa2acfd82192343a431d4c5b6
https://pubmed.ncbi.nlm.nih.gov/20739746
https://pubmed.ncbi.nlm.nih.gov/20739746
Autor:
Kevin M. Smith, Paul W. Naumann, John A. Thorson, John D. Kemp, Francisco Gomez, Janelle M. Mayer
Publikováno v:
Pathobiology. 60:27-32
One approach to creating a state of iron deprivation in tumors is to expose them to monoclonal antibodies against the transferrin receptor (ATRAs). This paper reviews the recent history of studies with ATRAs. Both multivalent (IgM or IgA) and bivalen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c8abb13e16a8a7aead151383dbe37f
https://doi.org/10.1159/000163693
https://doi.org/10.1159/000163693
Autor:
Lawrence J. Kanner, Kevin M. Smith, Paul W. Naumann, Francisco Gomez, John A. Thorson, John D. Kemp
Publikováno v:
Blood. 76:991-995
Data are presented indicating that the growth of 5 out of 5 murine lymphoid tumors can be inhibited in a synergistic fashion in vitro by combined treatment with the iron chelator deferoxamine (DFO) and an immunoglobulin G (IgG) monoclonal anti-transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4176ca1bdb63f89f089b7962d4a0db
https://doi.org/10.1182/blood.v76.5.991.991
https://doi.org/10.1182/blood.v76.5.991.991