Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Paul W N, Lee"'
Autor:
Yue, Pan, Min, Cao, Jianzhou, Liu, Qing, Yang, Xiaoyu, Miao, Vay Liang W, Go, Paul W N, Lee, Gary Guishan, Xiao
Publikováno v:
Advances in experimental medicine and biology. 1038
Mitochondria are generally considered as a powerhouse in a cell where the majority of the cellular ATP and metabolite productions occur. Metabolic rewiring and reprogramming may be initiated and regulated by mitochondrial enzymes. The hypothesis that
Autor:
Adrian Benito, Silvia Marin, Ibrahim H. Polat, Esther Aguilar, Vitaly A. Selivanov, Anibal Miranda, Marta Cascante, Paul W. N. Lee, Anusha Jayaraman, Josep J. Centelles
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
BMC Bioinformatics
BMC Bioinformatics, 2016, 18 (1), pp.88. ⟨10.1186/s12859-017-1513-3⟩
Dipòsit Digital de la UB
Universidad de Barcelona
instname
BMC Bioinformatics
BMC Bioinformatics, 2016, 18 (1), pp.88. ⟨10.1186/s12859-017-1513-3⟩
Dipòsit Digital de la UB
Universidad de Barcelona
Background: Tracing stable isotopes, such as 13C using various mass spectrometry (MS) methods provides a valuable information necessary for the study of biochemical processes in cells. However, extracting such information requires special care, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4ff6929683d4179833506a8d4a7584
http://hdl.handle.net/2445/112072
http://hdl.handle.net/2445/112072
Autor:
Gary Guishan Xiao, Paul W. N. Lee, Vay Liang W. Go, Jianzhou Liu, Xiaoyu Miao, Yue Pan, Qing Yang, Min Cao
Publikováno v:
Mitochondrial DNA and Diseases ISBN: 9789811066733
Mitochondria are generally considered as a powerhouse in a cell where the majority of the cellular ATP and metabolite productions occur. Metabolic rewiring and reprogramming may be initiated and regulated by mitochondrial enzymes. The hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e2be9fead9248b05bb6200f7046fa6
https://doi.org/10.1007/978-981-10-6674-0_11
https://doi.org/10.1007/978-981-10-6674-0_11
Publikováno v:
Metabolism. 62:432-441
Postnatal calorie and growth restriction (PNGR) in the first generation (F1) rat female offspring causes a lean and glucose tolerant phenotype associated with hypoinsulinemia and reduced glucose-stimulated insulin secretion (GSIS). Despite the absenc
Autor:
Ronald S. Swerdloff, Monica Schwarcz, Christina Wang, Amiya P. Sinha Hikim, Deena Abuyounes, Peter Liu, Krista Erkkilä, Yanhe Lue, J. David Jentsch, Paul W. N. Lee
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 299:E446-E455
XXY men (Klinefelter syndrome) are testosterone deficient, socially isolated, exhibit impaired gender identity, and may experience more homosexual behaviors. Here, we characterize social behaviors in a validated XXY mouse model to understand mechanis
Autor:
Manikkavasagar Thamotharan, Duncan C. MacLaren, Sherin U. Devaskar, Paul W. N. Lee, Gerald Pan, Shilpa A. Oak, Meena Garg
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 296:E272-E281
We examined the effect of early exercise training (Ex) on glucose kinetics, basal, and insulin-stimulated skeletal muscle (SKM) plasma membrane (PM) GLUT4 in pre- and/or postnatal nutrient-restricted adult rat offspring compared with sedentary (Sed)
Autor:
Ronald S. Swerdloff, Victor H.H. Goh, Steve Shiraishi, Christina Wang, Paul W. N. Lee, Andrew Leung
Publikováno v:
Clinical Chemistry. 54:1855-1863
Background: Recent reports have described inherent problems with androgen immunoassays compared with mass spectrometry analyses. Methods: We developed a method for measuring serum testosterone (T) and 5α-dihydrotestosterone (DHT) simultaneously via
Publikováno v:
Journal of Neurotrauma. 24:181-194
The metabolism of [1, 2 (13)C(2)] glucose via the tricarboxylic acid (TCA) cycle yields a number of key glutamate mass isotopomers whose formation is a function of pyruvate carboxylase (PC) and pyruvate dehydrogenase (PDH). Analysis of the isotopomer
Publikováno v:
Bioinformatics. 22:2806-2812
Motivation: Metabolic flux analysis of biochemical reaction networks using isotope tracers requires software tools that can analyze the dynamics of isotopic isomer (isotopomer) accumulation in metabolites and reveal the underlying kinetic mechanisms
Autor:
Jonathan D. Kaunitz, Eli Engel, Tetsu Takeuchi, Misa Mizumori, Claudiu T. Supuran, Paul H. Guth, Shu Lim, Paul W. N. Lee, Justin G. Meyerowitz, Yasutada Akiba
Publikováno v:
The Journal of Physiology. 573:827-842
The duodenum must absorb ∼450 mmol of H+ per 24 h in order to decrease [H+] of the luminal content by 6 log orders over its 15 cm length (Feldman & Colturi, 1984). HCl in the duodenal lumen is neutralized by HCO3− secreted by the pancreas and duo