Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Paul W Chrystal"'
Autor:
Adrian Santos-Ledo, Sam Washer, Tamil Dhanaseelan, Lorraine Eley, Ahlam Alqatani, Paul W Chrystal, Tania Papoutsi, Deborah J Henderson, Bill Chaudhry
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008782 (2020)
The planar cell polarity pathway is required for heart development and whilst the functions of most pathway members are known, the roles of the jnk genes in cardiac morphogenesis remain unknown as mouse mutants exhibit functional redundancy, with ear
Externí odkaz:
https://doaj.org/article/63f52ccabfb1416fa57b572b534e0b57
Autor:
Michael A. Walter, W. Ted Allison, Justin A. Jensen, Paul W. Chrystal, Elizabeth Hodges, Tim Footz
Publikováno v:
Molecules, Vol 26, Iss 3529, p 3529 (2021)
Molecules
Volume 26
Issue 12
Molecules
Volume 26
Issue 12
The ancient paralogs premelanosome protein (PMEL) and glycoprotein nonmetastatic melanoma protein B (GPNMB) have independently emerged as intriguing disease loci in recent years. Both proteins possess common functional domains and variants that cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9a66097972a622fe86b90ed81bc5ad
https://www.mdpi.com/1420-3049/26/12/3529
https://www.mdpi.com/1420-3049/26/12/3529
Autor:
Ian M. MacDonald, Curtis R. French, Fred B. Berry, Jagannadha Avasarala, Andrew J. Waskiewicz, Serhiy Havrylov, R Curtis Rogers, Suey van Baarle, Ordan J. Lehmann, Paul W. Chrystal, Tsutomu Kume
Alterations to cilia are responsible for a wide range of severe disease; however, understanding of the transcriptional control of ciliogenesis remains incomplete. We evaluated whether ciliary dysfunction contributed to the pleiotropic phenotypes caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f4801a2a11d3762abfa8ed5c9a3cc3c
https://doi.org/10.1101/2020.08.13.249334
https://doi.org/10.1101/2020.08.13.249334
Autor:
Suey van Baarle, Ordan J. Lehmann, Paul W. Chrystal, Serhiy Havrylov, Curtis R. French, David B. Pilgrim, Andrew J. Waskiewicz, Ann-Marie Peturson, J. Gage Crump, Pengfei Xu, Francesca Jean
Normal body situs requires precise spatiotemporal expression of theNodal-Lefty-Pitx2cascade in the lateral plate mesoderm. The ultimate output of this patterning is establishment of the left-right axis, which provides vital cues for correct organ for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07a9c8684ed92c80921d6554c38c4284
https://doi.org/10.1101/2020.05.28.120915
https://doi.org/10.1101/2020.05.28.120915
Autor:
Michael A. Walter, Paul W. Chrystal
Publikováno v:
Experimental eye research. 189
Aniridia and Axenfeld-Rieger Syndrome are related, human ocular disorders that are typically inherited in an autosomal dominant manner. Both result from incorrect development of the eye and have, as their most serious consequences, elevated risk to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db25849cccf6bd1a01318380f73766b5
https://pubmed.ncbi.nlm.nih.gov/31560925
https://pubmed.ncbi.nlm.nih.gov/31560925
Autor:
Ordan J. Lehmann, Paul W. Chrystal, Nathan D. Lawson, Matthew L. Workentine, Lihua Julie Zhu, Nicole M. Munsie, Andrew J. Waskiewicz, Ann S. Grosse, Thomas Whitesell, Jae-Ryeon Ryu, Sarah J. Childs, Curtis R. French, Rui Li
Publikováno v:
Developmental biology. 453(1)
Vascular smooth muscle of the head derives from neural crest, but developmental mechanisms and early transcriptional drivers of the vSMC lineage are not well characterized. We find that in early development, the transcription factor foxc1b is express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28162181a44daaa5088c59f38846c5ae
https://pubmed.ncbi.nlm.nih.gov/31199900
https://pubmed.ncbi.nlm.nih.gov/31199900
Autor:
Deborah J. Henderson, S. J. Washer, Paul W. Chrystal, Tania Papoutsi, T. Dhanaseelan, Adrian Santos-Ledo, Bill Chaudhry
Alternative splicing is a ubiquitous mechanism for producing different mRNA species from a single gene, resulting in proteomic diversity. Despite potential for regulating embryogenesis, its developmental role remains under-investigated. The Jun kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa88c72136531def55f32633c884765
https://doi.org/10.1101/546184
https://doi.org/10.1101/546184
Autor:
Francesca Jean, Curtis R. French, J. Gage Crump, Suey van Baarle, Pengfei Xu, Andrew J. Waskiewicz, Serhiy Havrylov, David B. Pilgrim, Ordan J. Lehmann, Paul W. Chrystal, Ann-Marie Peturson
Publikováno v:
Genes
Volume 12
Issue 2
Genes, Vol 12, Iss 170, p 170 (2021)
Volume 12
Issue 2
Genes, Vol 12, Iss 170, p 170 (2021)
Precise spatiotemporal expression of the Nodal-Lefty-Pitx2 cascade in the lateral plate mesoderm establishes the left&ndash
right axis, which provides vital cues for correct organ formation and function. Mutations of one cascade constituent PITX
right axis, which provides vital cues for correct organ formation and function. Mutations of one cascade constituent PITX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad67cab269bd714d4b564be22788ebbf
https://doi.org/10.3390/genes12020170
https://doi.org/10.3390/genes12020170
Autor:
Paul W. Chrystal, Ahlam Alqatani, Tamil Dhanaseelan, Bill Chaudhry, Deborah J. Henderson, Sam Washer, Lorraine Eley, Tania Papoutsi, Adrian Santos-Ledo
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 5, p e1008782 (2020)
PLoS Genetics, Vol 16, Iss 5, p e1008782 (2020)
The planar cell polarity pathway is required for heart development and whilst the functions of most pathway members are known, the roles of the jnk genes in cardiac morphogenesis remain unknown as mouse mutants exhibit functional redundancy, with ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3d66be7466d6173f39dd279efae1ff
https://doi.org/10.1371/journal.pgen.1008782
https://doi.org/10.1371/journal.pgen.1008782
Autor:
Lihua Julie Zhu, Curtis R. French, Thomas Whitesell, Matthew L. Workentine, Nicole M. Munsie, Jae-Ryeon Ryu, Andrew J. Waskiewicz, Ordan J. Lehmann, Paul W. Chrystal, Sarah J. Childs, Grosse A, Nathan D. Lawson, Rui Li
Despite the critical role of vascular mural cells (smooth muscle cells and pericytes) in supporting the endothelium of blood vessels, we know little of their early morphogenesis and differentiation.foxc1b:EGFPexpressing cells in zebrafish associate w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d743fca5ebc79ed0f7011a32e77d1e0
https://doi.org/10.1101/414003
https://doi.org/10.1101/414003