Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Paul V. Attwood"'
Autor:
Thomas Wieland, Paul V. Attwood
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Reversible phosphorylation of amino acid side chains in proteins is a frequently used mechanism in cellular signal transduction and alterations of such phosphorylation patterns are very common in cardiovascular diseases. They reflect changes in the a
Externí odkaz:
https://doaj.org/article/4f18adc30ae14eadac1ee3945ee7f7c5
Publikováno v:
Advances in experimental medicine and biology. 1286
Several studies have exploited the metabolic hallmarks that distinguish between normal and cancer cells, aiming at identifying specific targets of anti-cancer drugs. It has become apparent that metabolic flexibility allows cancer cells to survive dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4921167fa48889d27e25e3f39f2aef54
https://pubmed.ncbi.nlm.nih.gov/33725343
https://pubmed.ncbi.nlm.nih.gov/33725343
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030550349
Several studies have exploited the metabolic hallmarks that distinguish between normal and cancer cells, aiming at identifying specific targets of anti-cancer drugs. It has become apparent that metabolic flexibility allows cancer cells to survive dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a7f84c48b4d9ae40d617239a5058d2
https://doi.org/10.1007/978-3-030-55035-6_2
https://doi.org/10.1007/978-3-030-55035-6_2
Autor:
Paul V. Attwood, Richmond Muimo
Publikováno v:
Laboratory Investigation. 98:283-290
Nucleoside diphosphate kinases (NDPKs) are multifunctional proteins encoded by the nme (non-metastatic cells) genes, also called NM23. NDPKs catalyze the transfer of γ-phosphate from nucleoside triphosphates to nucleoside diphosphates by a ping-pong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a82cf14416e97457a9f9af5f8a6f607
https://doi.org/10.1038/labinvest.2017.125
https://doi.org/10.1038/labinvest.2017.125
Publikováno v:
Archives of Biochemistry and Biophysics. 711:109017
A previous study showed that 2'-3'-O-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP) was a weak allosteric activator of Rhizobium etli pyruvate carboxylase (RePC) in the absence of acetyl-CoA. On the other hand, TNP-ATP inhibited the allos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bfebe38fe0992c1bce50579e00c628
https://doi.org/10.1016/j.abb.2021.109017
https://doi.org/10.1016/j.abb.2021.109017
Publikováno v:
Biochemistry and Molecular Biology Education. 46:130-140
Assessment is a central component of course curriculums and is used to certify student learning, but it can also be used as a tool to improve teaching and learning. Many laboratory courses are structured such that there is only a grade for a particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a88b82a74d70f2e0ebc7443aca1a2fb
https://doi.org/10.1002/bmb.21104
https://doi.org/10.1002/bmb.21104
Autor:
Paul V. Attwood, Matthew J. Piggott
Publikováno v:
Amino Acids. 49:1309-1323
The synthesis and chemistry of the lesser-known phosphoamino acids, O-phosphohydroxylysine, O-phosphohydroxyproline, N 1-phosphotryptophan and S-phosphocysteine are described in detail. In addition, where anything at all is known, the biological synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de016a4f8800cd56155e8dba21e64ef9
https://doi.org/10.1007/s00726-017-2446-x
https://doi.org/10.1007/s00726-017-2446-x
Autor:
Paul V, Attwood
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2077
The method described in this chapter provides a quantitative means of assaying for protein histidine phosphorylation and thus protein histidine kinase activity, even in the presence of other protein kinases, for example, serine/threonine or tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36da9e1724be13db4251eb8bc5d3b964
https://pubmed.ncbi.nlm.nih.gov/31707651
https://pubmed.ncbi.nlm.nih.gov/31707651
Publikováno v:
Biochemistry. 55:4220-4228
The mechanism of allosteric activation of pyruvate carboxylase by acetyl CoA is not fully understood. Here we have examined the roles of residues near the acetyl CoA binding site in the allosteric activation of Rhizobium etli pyruvate carboxylase usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767d4d0b8550bcf9288e3292d6b2a03c
https://doi.org/10.1021/acs.biochem.6b00548
https://doi.org/10.1021/acs.biochem.6b00548
Publikováno v:
Biochemistry and Molecular Biology Education. 44:276-287
A new laboratory practical system is described which is comprised of a number of laboratory practical modules, each based around a particular technique or set of techniques, related to the theory part of the course but not designed to be dependent on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29ca39dfbe3f58dcf99e01c93c445552
https://doi.org/10.1002/bmb.20951
https://doi.org/10.1002/bmb.20951