Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Paul Tolstoshev"'
Autor:
Paul Tolstoshev, Anthony J F D'Apice, Christopher G. Grupen, Peter J. Cowan, Ian Lyons, Allan J. Robins, Christopher Giannakis, A.C. Boquest, Stephen M. McIlfatrick, Renate Faast, Angelo Guildolin, Lesley Crocker, R.J. Ashman, James Wengle, Philip J. O'Connell, Mark B. Nottle, Sharon J. Harrison
Publikováno v:
Scopus-Elsevier
We have reported relatively efficient methods for somatic cell nuclear transfer and for knocking out the alpha(1,3)-galactosyltransferase (alpha1,3-GT) gene in porcine fetal fibroblasts using a nonisogenic promoterless construct approach. Here we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015db991c60b52ca3337c7a1c19f1e95
https://doi.org/10.1089/clo.2004.6.327
https://doi.org/10.1089/clo.2004.6.327
Autor:
Cynthia Dunbar, Donald Kohn, Stefan Karlsson, Norman Barton, Roscoe Brady, Michele Cottler-Fox, Gay Crooks, Robert Emmons, Joan Esplin, Susan Leitman, Carl Lenarsky, Jan Nolta, Robertson Parkman, Michael Pensiero, Raphael Schifmann, Paul Tolstoshev, Kenneth Weinberg
Publikováno v:
Human Gene Therapy. 7:231-253
Patients with Gaucher disease suffer from a lack of functional glucocerebrosidase enzyme (Gc). Disease symptoms are a result of macrophage engorgement secondary to this enzyme deficiency. This study is designed to determine if cDNA encoding normal Gc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d849920abecbb8978f86c6a08d1650af
https://doi.org/10.1089/hum.1996.7.2-231
https://doi.org/10.1089/hum.1996.7.2-231
Autor:
Paul Tolstoshev, Bruce C. Trapnell, Soonpin Yei, Jeffrey A. Whitsett, John Cuppoletti, Cindy J. Bachurski, Nanette Mittereder
Publikováno v:
Human gene therapy. 5(6)
Cystic fibrosis (CF) is a common, fatal recessive disease caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene manifested by abnormalities in the regulation of chloride ion (Cl-) secretion across the apical membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39eb54e2dd27ba941252c5d04e4ced5
https://pubmed.ncbi.nlm.nih.gov/7948134
https://pubmed.ncbi.nlm.nih.gov/7948134
Autor:
W. French Anderson, Paul Tolstoshev
Publikováno v:
Current opinion in biotechnology. 1(1)
The objective of this review is to consider the most significant advances that have been made in the past few years in the use of retroviral vectors for gene expression. Undoubtedly, one of the most significant of these has been the first sanctioned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc8e68414e011c2c8c7a7b5ba2c0b2a
https://pubmed.ncbi.nlm.nih.gov/1367917
https://pubmed.ncbi.nlm.nih.gov/1367917
Autor:
Paul Tolstoshev
Publikováno v:
Human Gene Therapy. 1:107-108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceed60358d94fb19c3b62a0d50f16fa5
https://doi.org/10.1089/hum.1990.1.1-107
https://doi.org/10.1089/hum.1990.1.1-107
Autor:
Sharon Harrison, Andrew Boquest, Christopher Grupen, Renate Faast, Angelo Guildolin, Christopher Giannakis, Lesley Crocker, Stephen McIlfatrick, Rodney Ashman, James Wengle, Ian Lyons, Paul Tolstoshev, Peter Cowan, Allan Robins, Philip O'Connell, Anthony J.F. D'Apice, Mark Nottle
Publikováno v:
Cloning & Stem Cells; Winter2004, Vol. 6 Issue 4, p327-331, 5p
Publikováno v:
Nucleic Acids Research. 8:3659-3672
Thermodynamically stable secondary structures have been found for adjacent splice junctions of 17 introns from 10 eukaryotic and viral mRNA precursors. Complementary regions in these structures position the exons to be ligated in a favourable orienta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e4edea6d169378e5dbb569141142df
https://doi.org/10.1093/nar/8.16.3659
https://doi.org/10.1093/nar/8.16.3659
Publikováno v:
Nucleic Acids Research. 8:2241-2254
A recombinant phage, SpC3, containing a 17 kb genomic DNA insert representing approximately 60% of the 3' portion of the sheep collagen alpha 2 gene, was evaluated by electron microscopic R loop analysis. A minimum of 17 intervening sequences (intron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c22e3967f0117aee8eb53ae5a765194
https://doi.org/10.1093/nar/8.10.2241
https://doi.org/10.1093/nar/8.10.2241
Autor:
Ronald G. Crystal, Raymond Dalgleish, Paul Tolstoshev, Stephen I. Rennard, M. Miskulin, Mark L. Brantly, Barbara Kluve-Beckerman
Publikováno v:
Biochemistry. 25:1408-1413
Type III collagen is one of the major interstitial collagens and, as such, plays an important role in modulating the structure and function of most tissues. To compare the expression of the type III collagen gene to that of the type I collagen alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f396ccf19fcb614cab531db95bcb4303
https://doi.org/10.1021/bi00354a033
https://doi.org/10.1021/bi00354a033
Publikováno v:
Gene. 2:147-158
A nuclease-sensitive fraction was obtained from chick reticulocyte chromatin by brief digestion with an endonuclease (DNAase II, deoxyribonucleate 3′-oligonucleotidohydrolase, EC 3.1.4.6). The nuclease-sensitive fraction typically contained less th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f748a5503e8eabc7692d3ac0a9af29
https://doi.org/10.1016/0378-1119(77)90014-2
https://doi.org/10.1016/0378-1119(77)90014-2